Publications by authors named "Fred Harbinski"

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TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A.
X Rosa Ma, Mercedes Prudencio, Yuka Koike, Sarat C Vatsavayai, Garam Kim, Fred Harbinski

Nature· March 2022

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Phenotypic screen identifies calcineurin-sparing FK506 analogs as BMP potentiators for treatment of acute kidney injury.
Marie-Hélène Larraufie, Xiaolin Gao, Xiaobo Xia, Patrick J Devine, Joerg Kallen, Fred Harbinski

Cell Chem Biol· September 2021

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SMOOT libraries and phage-induced directed evolution of Cas9 to engineer reduced off-target activity.
Derek Cerchione, Katherine Loveluck, Eric L Tillotson, Fred Harbinski, Jen DaSilva

PLoS One· August 2020

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Recurrent ubiquitin B silencing in gynecological cancers establishes dependence on ubiquitin C.
Alexia T Kedves, Scott Gleim, Xiaoyou Liang, Dennis M Bonal, Frederic Sigoillot, Fred Harbinski

J Clin Invest· December 2017

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Jenkins-CI, an Open-Source Continuous Integration System, as a Scientific Data and Image-Processing Platform.
Ioannis K Moutsatsos, Imtiaz Hossain, Claudia Agarinis, Fred Harbinski, Yann Abraham

SLAS Discov· March 2017

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High-Order Drug Combinations Are Required to Effectively Kill Colorectal Cancer Cells.
Thomas Horn, Stéphane Ferretti, Nicolas Ebel, Angela Tam, Samuel Ho, Fred Harbinski

Cancer Res· December 2016

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Metabolic Enzyme Sulfotransferase 1A1 Is the Trigger for N-Benzyl Indole Carbinol Tumor Growth Suppression.
Deborah M Rothman, Xiaolin Gao, Elizabeth George, Timothy Rasmusson, Diksha Bhatia, Fred Harbinski

Chem Biol· September 2015

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Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.
William E Dowdle, Beat Nyfeler, Jane Nagel, Robert A Elling, Shanming Liu, Fred Harbinski

Nat Cell Biol· November 2014

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Identification of mixed lineage leukemia 1(MLL1) protein as a coactivator of heat shock factor 1(HSF1) protein in response to heat shock protein 90 (HSP90) inhibition.
Yaoyu Chen, Jinyun Chen, Jianjun Yu, Guizhi Yang, Emilia Temple, Fred Harbinski

J Biol Chem· July 2014

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Target identification for a Hedgehog pathway inhibitor reveals the receptor GPR39.
Frederic Bassilana, Adam Carlson, Jennifer A DaSilva, Bianka Grosshans, Solange Vidal, Fred Harbinski

Nat Chem Biol· May 2014

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Small-Molecule targeting of translation initiation for cancer therapy.
Bertal H Aktas, Yuan Qiao, Esra Ozdelen, Roland Schubert, Sema Sevinc, Fred Harbinski

Oncotarget· October 2013

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Reporter enzyme inhibitor study to aid assembly of orthogonal reporter gene assays.
Pei-i Ho, Kimberley Yue, Pramod Pandey, Lyne Breault, Fred Harbinski

ACS Chem Biol· May 2013

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Rescue screens with secreted proteins reveal compensatory potential of receptor tyrosine kinases in driving cancer growth.
Fred Harbinski, Vanessa J Craig, Sneha Sanghavi, Douglas Jeffery, Lijuan Liu

Cancer Discov· October 2012

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Chemical genetics identify eIF2α kinase heme-regulated inhibitor as an anticancer target.
Ting Chen, Duygu Ozel, Yuan Qiao, Fred Harbinski, Limo Chen

Nat Chem Biol· July 2011

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Synthesis and biological evaluation of thiazolidine-2,4-dione and 2,4-thione derivatives as inhibitors of translation initiation.
Han Chen, Yun-Hua Fan, Amarnath Natarajan, Yuhong Guo, Julia Iyasere, Fred Harbinski

Bioorg Med Chem Lett· November 2004

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Structure-activity requirements for the antiproliferative effect of troglitazone derivatives mediated by depletion of intracellular calcium.
Yun-Hua Fan, Han Chen, Amarnath Natarajan, Yuhong Guo, Fred Harbinski

Bioorg Med Chem Lett· May 2004

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