Publications by authors named "Frederic Allemand"

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Neutral peptides allow aggregation of cationic peptides in antimicrobial secretory fluids.
Peicho Petkov, Rositsa Marinova, Leandar Litov, Petya Sirakova, Elena Lilkova, Frédéric Allemand

Biochem Biophys Res Commun· September 2025

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Towards the design of ligands of the internal pocket TEADs C-terminal domain.
Florine Toulotte, Mathilde Coevoet, Maxime Liberelle, Fabrice Bailly, Benjamin Zagiel, Frédéric Allemand

Eur J Med Chem· January 2025

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Site-Specific Incorporation of Fluorinated Prolines into Proteins and Their Impact on Neighbouring Residues.
Carlos A Elena-Real, Annika Urbanek, Amin Sagar, Priyesh Mohanty, Geraldine Levy, Frédéric Allemand

Chemistry· January 2025

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Development of HC-258, a Covalent Acrylamide TEAD Inhibitor That Reduces Gene Expression and Cell Migration.
Ahmed Fnaiche, Hwai-Chien Chan, Alexis Paquin, Narjara González Suárez, Victoria Vu, Frédéric Allemand

ACS Med Chem Lett· December 2023

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Phosphorylation motif dictates GPCR C-terminal domain conformation and arrestin interaction.
Myriam Guillien, Assia Mouhand, Amin Sagar, Aurélie Fournet, Frédéric Allemand

Structure· November 2023

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Development of LM-41 and AF-2112, two flufenamic acid-derived TEAD inhibitors obtained through the replacement of the trifluoromethyl group by aryl rings.
Ahmed Fnaiche, Léa Mélin, Narjara González Suárez, Alexis Paquin, Victoria Vu, Frédéric Allemand

Bioorg Med Chem Lett· October 2023

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Site-Specific Introduction of Alanines for the Nuclear Magnetic Resonance Investigation of Low-Complexity Regions and Large Biomolecular Assemblies.
Carlos A Elena-Real, Annika Urbanek, Lionel Imbert, Anna Morató, Aurélie Fournet, Frédéric Allemand

ACS Chem Biol· September 2023

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Multi-site-specific isotopic labeling accelerates high-resolution structural investigations of pathogenic huntingtin exon-1.
Carlos A Elena-Real, Annika Urbanek, Xamuel L Lund, Anna Morató, Amin Sagar, Frédéric Allemand

Structure· June 2023

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The structure of pathogenic huntingtin exon 1 defines the bases of its aggregation propensity.
Carlos A Elena-Real, Amin Sagar, Annika Urbanek, Matija Popovic, Anna Morató, Frédéric Allemand

Nat Struct Mol Biol· March 2023

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A Flexible and Original Architecture of Two Unrelated Zinc Fingers Underlies the Role of the Multitask P1 in RYMV Spread.
Vianney Poignavent, François Hoh, Guillaume Terral, Yinshan Yang, François-Xavier Gillet, Frédéric Allemand

J Mol Biol· August 2022

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Toward the Design of Ligands Selective for the C-Terminal Domain of TEADs.
Maxime Liberelle, Florine Toulotte, Nicolas Renault, Muriel Gelin, Frédéric Allemand

J Med Chem· April 2022

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Structural Insights into the Intrinsically Disordered GPCR C-Terminal Region, Major Actor in Arrestin-GPCR Interaction.
Myriam Guillien, Assia Mouhand, Aurélie Fournet, Amandine Gontier, Aleix Martí Navia, Frédéric Allemand

Biomolecules· April 2022

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Discovery of a cryptic site at the interface 2 of TEAD - Towards a new family of YAP/TAZ-TEAD inhibitors.
Manon Sturbaut, Fabrice Bailly, Mathilde Coevoet, Pasquale Sileo, Martine Pugniere, Frédéric Allemand

Eur J Med Chem· December 2021

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Design, Synthesis and Evaluation of a Series of 1,5-Diaryl-1,2,3-triazole-4-carbohydrazones as Inhibitors of the YAP-TAZ/TEAD Complex.
Floriane Gibault, Manon Sturbaut, Mathilde Coevoet, Martine Pugnière, Ashley Burtscher, Frédéric Allemand

ChemMedChem· September 2021

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Δ133p53β isoform pro-invasive activity is regulated through an aggregation-dependent mechanism in cancer cells.
Nikola Arsic, Tania Slatter, Gilles Gadea, Etienne Villain, Aurelie Fournet, Frédéric Allemand

Nat Commun· September 2021

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Structural Insights into the Interaction of the Intrinsically Disordered Co-activator TIF2 with Retinoic Acid Receptor Heterodimer (RXR/RAR).
Lucile Senicourt, Albane le Maire, Frédéric Allemand, JoÃo E Carvalho, Laura Guee

J Mol Biol· April 2021

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An Optimized and Standardized Rapid Flow Cytometry Functional Method for Heparin-Induced Thrombocytopenia.
Anne Runser, Caroline Schaning, Frédéric Allemand, Jean Amiral

Biomedicines· March 2021

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Robust Cell-Free Expression of Sub-Pathological and Pathological Huntingtin Exon-1 for NMR Studies. General Approaches for the Isotopic Labeling of Low-Complexity Proteins.
Anna Morató, Carlos A Elena-Real, Matija Popovic, Aurélie Fournet, Karen Zhang, Frédéric Allemand

Biomolecules· October 2020

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Flanking Regions Determine the Structure of the Poly-Glutamine in Huntingtin through Mechanisms Common among Glutamine-Rich Human Proteins.
Annika Urbanek, Matija Popovic, Anna Morató, Alejandro Estaña, Carlos A Elena-Real, Frédéric Allemand

Structure· July 2020

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Evidence of the Reduced Abundance of Proline cis Conformation in Protein Poly Proline Tracts.
Annika Urbanek, Matija Popovic, Carlos A Elena-Real, Anna Morató, Alejandro Estaña, Frédéric Allemand

J Am Chem Soc· April 2020

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Site-Specific Isotopic Labeling (SSIL): Access to High-Resolution Structural and Dynamic Information in Low-Complexity Proteins.
Annika Urbanek, Carlos A Elena-Real, Matija Popovic, Anna Morató, Aurélie Fournet, Frédéric Allemand

Chembiochem· March 2020

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Interplay of Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression.
Tiago N Cordeiro, Nathalie Sibille, Pierre Germain, Philippe Barthe, Abdelhay Boulahtouf, Fréderic Allemand

Structure· August 2019

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Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation.
Céline Lecointre, Valérie Simon, Clément Kerneur, Frédéric Allemand, Aurélie Fournet

Structure· November 2018

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Toward the Discovery of a Novel Class of YAP⁻TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP⁻TEAD Protein⁻Protein Interface.
Floriane Gibault, Mathilde Coevoet, Manon Sturbaut, Amaury Farce, Nicolas Renault, Frédéric Allemand

Cancers (Basel)· May 2018

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Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation.
Céline Lecointre, Valérie Simon, Clément Kerneur, Frédéric Allemand, Aurélie Fournet

Structure· April 2018

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