Publications by authors named "Mathilde Coevoet"

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Towards the design of ligands of the internal pocket TEADs C-terminal domain.
Florine Toulotte, Mathilde Coevoet, Maxime Liberelle, Fabrice Bailly, Benjamin Zagiel

Eur J Med Chem· January 2025

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Novel Quinazoline Derivatives as Highly Effective A2A Adenosine Receptor Antagonists.
Amélie Laversin, Robin Dufossez, Raphaël Bolteau, Romain Duroux, Séverine Ravez, Mathilde Coevoet

Molecules· August 2024

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High ligand efficiency quinazoline compounds as novel A adenosine receptor antagonists.
Raphaël Bolteau, Romain Duroux, Amélie Laversin, Brandon Vreulz, Anna Shiriaeva, Mathilde Coevoet

Eur J Med Chem· November 2022

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Discovery of Compounds That Selectively Repress the Amyloidogenic Processing of the Amyloid Precursor Protein: Design, Synthesis and Pharmacological Evaluation of Diphenylpyrazoles.
Christophe Mesangeau, Pascal Carato, Nicolas Renault, Mathilde Coevoet, Paul-Emmanuel Larchanché

Int J Mol Sci· October 2022

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Discovery of a cryptic site at the interface 2 of TEAD - Towards a new family of YAP/TAZ-TEAD inhibitors.
Manon Sturbaut, Fabrice Bailly, Mathilde Coevoet, Pasquale Sileo, Martine Pugniere

Eur J Med Chem· December 2021

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Design, Synthesis and Evaluation of a Series of 1,5-Diaryl-1,2,3-triazole-4-carbohydrazones as Inhibitors of the YAP-TAZ/TEAD Complex.
Floriane Gibault, Manon Sturbaut, Mathilde Coevoet, Martine Pugnière, Ashley Burtscher

ChemMedChem· September 2021

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New piperazine multi-effect drugs prevent neurofibrillary degeneration and amyloid deposition, and preserve memory in animal models of Alzheimer's disease.
Nicolas Sergeant, Valérie Vingtdeux, Sabiha Eddarkaoui, Marion Gay, Caroline Evrard, Mathilde Coevoet

Neurobiol Dis· September 2019

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A phenotypic approach to the discovery of compounds that promote non-amyloidogenic processing of the amyloid precursor protein: Toward a new profile of indirect β-secretase inhibitors.
Marion Gay, Caroline Evrard, Florian Descamps, Pascal Carato, Nicolas Renault, Mathilde Coevoet

Eur J Med Chem· November 2018

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Contribution of the Endosomal-Lysosomal and Proteasomal Systems in Amyloid-β Precursor Protein Derived Fragments Processing.
Caroline Evrard, Pascal Kienlen-Campard, Mathilde Coevoet, Rémi Opsomer, Bernadette Tasiaux

Front Cell Neurosci· November 2018

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Design and synthesis of 2,6-disubstituted-8-amino imidazo[1,2a]pyridines, a promising privileged structure.
Rajaa Boulahjar, Angela Rincon Arias, Raphaël Bolteau, Nicolas Renault, Mathilde Coevoet

Bioorg Med Chem· July 2018

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New phenylaniline derivatives as modulators of amyloid protein precursor metabolism.
Marion Gay, Pascal Carato, Mathilde Coevoet, Nicolas Renault, Paul-Emmanuel Larchanché

Bioorg Med Chem· May 2018

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Toward the Discovery of a Novel Class of YAP⁻TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP⁻TEAD Protein⁻Protein Interface.
Floriane Gibault, Mathilde Coevoet, Manon Sturbaut, Amaury Farce, Nicolas Renault

Cancers (Basel)· May 2018

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Molecular Features of the YAP Inhibitor Verteporfin: Synthesis of Hexasubstituted Dipyrrins as Potential Inhibitors of YAP/TAZ, the Downstream Effectors of the Hippo Pathway.
Floriane Gibault, Fabrice Bailly, Matthieu Corvaisier, Mathilde Coevoet, Guillemette Huet

ChemMedChem· June 2017

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