Publications by authors named "Pascal Carato"

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Discovery of Novel Benzamide-Based Sigma-1 Receptor Agonists with Enhanced Selectivity and Safety.
Pascal Carato, Bénédicte Oxombre, Séverine Ravez, Rajaa Boulahjar, Marion Donnier-Maréchal

Molecules· September 2025

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Effects and risk assessment of halogenated bisphenol A derivatives on human follicle stimulating hormone receptor: An interdisciplinary study.
Valentine Suteau, Lorena Zuzic, Ditlev Høj Hansen, Lisbeth R Kjølbye, Paul Sibilia, Pascal Carato

J Hazard Mater· November 2024

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Formation of halogenated forms of bisphenol A (BPA) in water: Resolving isomers with ion mobility - mass spectrometry and the role of halogenation position in cellular toxicity.
Mauricius Marques Dos Santos, Caixia Li, Shenglan Jia, Mikael Thomas, Hervé Gallard, Pascal Carato

J Hazard Mater· March 2024

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Quantification of the Conjugated Forms of Dichlorobisphenol A (3,3'-Cl 2 BPA) in Rat and Human Plasma Using HPLC-MS/MS.
Noemie Plattard, Riciga Gnanasegaran, Aida Krekesheva, Pascal Carato, Antoine Dupuis

Ther Drug Monit· August 2023

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Characterization of pregnant women exposure to halogenated parabens and bisphenols through water consumption.
Marion Albouy, Yoann Deceuninck, Virginie Migeot, Manon Doumas, Antoine Dupuis, Pascal Carato

J Hazard Mater· April 2023

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Discovery of Compounds That Selectively Repress the Amyloidogenic Processing of the Amyloid Precursor Protein: Design, Synthesis and Pharmacological Evaluation of Diphenylpyrazoles.
Christophe Mesangeau, Pascal Carato, Nicolas Renault, Mathilde Coevoet, Paul-Emmanuel Larchanché

Int J Mol Sci· October 2022

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Genotoxic effects of chlorinated disinfection by-products of 1,3-diphenylguanidine (DPG): Cell-based in-vitro testing and formation potential during water disinfection.
Mauricius Marques Dos Santos, Camille Cheriaux, Shenglan Jia, Mikael Thomas, Hervé Gallard, Pascal Carato

J Hazard Mater· August 2022

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Effect of 6-Benzoyl-benzothiazol-2-one scaffold on the pharmacological profile of α-alkoxyphenylpropionic acid derived PPAR agonists.
Aurélie Hurtevent, Morgan Le Naour, Veronique Leclerc, Pascal Carato, Patricia Melnyk

J Enzyme Inhib Med Chem· December 2020

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New piperazine multi-effect drugs prevent neurofibrillary degeneration and amyloid deposition, and preserve memory in animal models of Alzheimer's disease.
Nicolas Sergeant, Valérie Vingtdeux, Sabiha Eddarkaoui, Marion Gay, Caroline Evrard, Pascal Carato

Neurobiol Dis· September 2019

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Benzo[d]thiazol-2(3H)-ones as new potent selective CB agonists with anti-inflammatory properties.
Natascha Leleu-Chavain, Davy Baudelet, Valéria Moas Heloire, Diana Escalante Rocha, Nicolas Renault, Pascal Carato

Eur J Med Chem· March 2019

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Chlorinated and brominated bisphenol A derivatives: Synthesis, characterization and determination in water samples.
Manon Doumas, Steeve Rouillon, Nicolas Venisse, Cedric Nadeau, Pascale Pierre Eugene, Pascal Carato

Chemosphere· December 2018

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A phenotypic approach to the discovery of compounds that promote non-amyloidogenic processing of the amyloid precursor protein: Toward a new profile of indirect β-secretase inhibitors.
Marion Gay, Caroline Evrard, Florian Descamps, Pascal Carato, Nicolas Renault

Eur J Med Chem· November 2018

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New phenylaniline derivatives as modulators of amyloid protein precursor metabolism.
Marion Gay, Pascal Carato, Mathilde Coevoet, Nicolas Renault, Paul-Emmanuel Larchanché

Bioorg Med Chem· May 2018

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Validation of a probe for assessing deconjugation of glucuronide and sulfate phase II metabolites assayed through LC-MS/MS in biological matrices.
Claire Grignon, Antoine Dupuis, Marion Albouy-Llaty, Maxime Condylis, Laurence Barrier, Pascal Carato

J Chromatogr B Analyt Technol Biomed Life Sci· September 2017

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Synthesis and pharmacological evaluation of benzamide derivatives as potent and selective sigma-1 protein ligands.
Marion Donnier-Maréchal, Pascal Carato, Paul-Emmanuel Larchanché, Séverine Ravez, Rajaa Boulahjar

Eur J Med Chem· September 2017

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Synthesis and pharmacological evaluation of benzannulated derivatives as potent and selective sigma-1 protein ligands.
Marion Donnier-Maréchal, Pascal Carato, Delphine Le Broc, Christophe Furman, Patricia Melnyk

Eur J Med Chem· March 2015

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6-Sulfonylbenzothiazolones as potential scaffolds for the design of 5-HT6 ligands.
Paul-Emmanuel Larchanche, Vincent Ultré, Delphine Le Broc, Céline Ballandone, Christophe Furman, Pascal Carato

Eur J Med Chem· March 2015

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Carboline- and phenothiazine-derivated heterocycles as potent SIGMA-1 protein ligands.
Marion Donnier-Maréchal, Paul-Emmanuel Larchanché, Delphine Le Broc, Christophe Furman, Pascal Carato

Eur J Med Chem· January 2015

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Antioxydant activity of β-carboline derivatives in the LDL oxidation model.
Fariza Hadjaz, Soizic Besret, Françoise Martin-Nizard, Saïd Yous, Sébastien Dilly, Pascal Carato

Eur J Med Chem· June 2011

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Synthesis, biological evaluation and docking studies of 4-amino-tetrahydroquinazolino[3,2-e]purine derivatives.
Valerie Verones, Nathalie Flouquet, Amaury Farce, Pascal Carato, Stephane Leonce

Eur J Med Chem· December 2010

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Antioxidant activity of benzoxazolinonic and benzothiazolinonic derivatives in the LDL oxidation model.
Ismaël Yekini, Fatma Hammoudi, Françoise Martin-Nizard, Saïd Yous, Nicolas Lebegue, Pascal Carato

Bioorg Med Chem· November 2009

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Benzopyridooxathiazepine derivatives as novel potent antimitotic agents.
Sebastien Gallet, Nathalie Flouquet, Pascal Carato, Bruno Pfeiffer, Pierre Renard

Bioorg Med Chem· February 2009

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Quantitative structure-activity relationships studies of antioxidant hexahydropyridoindoles and flavonoid derivatives.
Anne-Catherine Durand, Amaury Farce, Pascal Carato, Sebastien Dilly, Said Yous

J Enzyme Inhib Med Chem· October 2007

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Synthesis and in vitro binding studies of substituted piperidine naphthamides. Part II: Influence of the substitution on the benzyl moiety on the affinity for D2L, D4.2, and 5-HT2A receptors.
Pascal Carato, Amaury Graulich, Niels Jensen, Bryan L Roth, Jean-François Liégeois

Bioorg Med Chem Lett· March 2007

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Synthesis and in vitro binding studies of substituted piperidine naphthamides. Part I: Influence of the substitution on the basic nitrogen and the position of the amide on the affinity for D2L, D4.2, and 5-HT2A receptors.
Pascal Carato, Amaury Graulich, Niels Jensen, Bryan L Roth, Jean-François Liégeois

Bioorg Med Chem Lett· March 2007

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