Publications by authors named "Frederic Buono"

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Leveraging an intelligent slug flow platform for self-optimization of reaction systems with categorical variables.
Florian L Wagner, Gernot Neun, Thomas Tampone, Zhen Lei, Frederic G Buono

Chem Sci· December 2025

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EvolvedComplexity as a Total Synthesis Assessment Metric: Strychnine as a Case Study of Scoring Functions.
Abbigayle E Cuomo, John-Paul Webster, H Ray Kelly, Sumon Sarkar, Yu Shee, Frederic Buono

J Org Chem· October 2025

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Oxoammonium-Catalyzed Oxidation of -Substituted Amines.
Jonas Rein, Bartosz Górski, Yukun Cheng, Zhen Lei, Frederic Buono

J Am Chem Soc· November 2024

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Site-specific template generative approach for retrosynthetic planning.
Yu Shee, Haote Li, Pengpeng Zhang, Andrea M Nikolic, Wenxin Lu, Frederic G Buono

Nat Commun· September 2024

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A Slug Flow Platform with Multiple Process Analytics Facilitates Flexible Reaction Optimization.
Florian Wagner, Peter Sagmeister, Clemens E Jusner, Thomas G Tampone, Vidhyadhar Manee, Frederic G Buono

Adv Sci (Weinh)· April 2024

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Feed-Forward Neural Network for Predicting Enantioselectivity of the Asymmetric Negishi Reaction.
Abbigayle E Cuomo, Sebastian Ibarraran, Sanil Sreekumar, Haote Li, Jungmin Eun, Frederic Buono

ACS Cent Sci· September 2023

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Autonomous Multi-Step and Multi-Objective Optimization Facilitated by Real-Time Process Analytics.
Peter Sagmeister, Florian F Ort, Clemens E Jusner, Dominique Hebrault, Thomas Tampone, Frederic G Buono

Adv Sci (Weinh)· April 2022

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Carbamoyl Anion Addition to Azirines.
Michael J Kerner, Christian A Kuttruff, Maxim Chevliakov, Frederic G Buono, Donghong A Gao

Org Lett· June 2021

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Application of a Preformed Pd-BIDIME Precatalyst to Suzuki-Miyaura Cross-Coupling Reaction in Flow.
Joshua D Sieber, Frederic Buono, Andrew Brusoe, Jean-Nicolas Desrosiers, Nizar Haddad

J Org Chem· April 2019

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Development of a Scalable, Chromatography-Free Synthesis of t-Bu-SMS-Phos and Application to the Synthesis of an Important Chiral CF-Alcohol Derivative with High Enantioselectivity Using Rh-Catalyzed Asymmetric Hydrogenation.
Joshua D Sieber, Sonia Rodriguez, Rogelio Frutos, Frederic Buono, Yongda Zhang

J Org Chem· February 2018

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Sequential C-H Arylation and Enantioselective Hydrogenation Enables Ideal Asymmetric Entry to the Indenopiperidine Core of an 11β-HSD-1 Inhibitor.
Xudong Wei, Bo Qu, Xingzhong Zeng, Jolaine Savoie, Keith R Fandrick, Frederic G Buono

J Am Chem Soc· November 2016

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Transnitrilation from Dimethylmalononitrile to Aryl Grignard and Lithium Reagents: A Practical Method for Aryl Nitrile Synthesis.
Jonathan T Reeves, Christian A Malapit, Frederic G Buono, Kanwar P Sidhu, Maurice A Marsini

J Am Chem Soc· July 2015

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Development of an asymmetric synthesis of a chiral quaternary FLAP inhibitor.
Keith R Fandrick, Jason A Mulder, Nitinchandra D Patel, Joe Gao, Michael Konrad, Frederic G Buono

J Org Chem· February 2015

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Synthesis of the 6-azaindole containing HIV-1 attachment inhibitor pro-drug, BMS-663068.
Ke Chen, Christina Risatti, Michael Bultman, Maxime Soumeillant, James Simpson, Frederic G Buono

J Org Chem· September 2014

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Addressing the configuration stability of lithiated secondary benzylic carbamates for the development of a noncryogenic stereospecific boronate rearrangement.
Keith R Fandrick, Nitinchandra D Patel, Jason A Mulder, Joe Gao, Michael Konrad, Frederic G Buono

Org Lett· September 2014

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Mechanistic insight into the palladium-catalyzed 1,4-oxidation of 1,3-dienes to 1,4-dicarboxy-alk-2-enes.
Martin D Eastgate, Frederic G Buono

Angew Chem Int Ed Engl· October 2009

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Insights into palladium-catalyzed cyanation of bromobenzene: additive effects on the rate-limiting step.
Frederic G Buono, Rama Chidambaram, Richard H Mueller, Robert E Waltermire

Org Lett· December 2008

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Remarkable beta-selectivity in the synthesis of beta-1-C-arylglucosides: stereoselective reduction of acetyl-protected methyl 1-C-arylglucosides without acetoxy-group participation.
Prashant P Deshpande, Bruce A Ellsworth, Frederic G Buono, Annie Pullockaran, Janak Singh

J Org Chem· December 2007

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Novel 1,4-homofragmentation via an alpha-lactone.
Jollie D Godfrey, Rita T Fox, Frederic G Buono, Jack Z Gougoutas, Mary F Malley

J Org Chem· October 2006

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Oxidative dehydrogenation of dihydropyrimidinones and dihydropyrimidines.
Kana Yamamoto, Ye Grace Chen, Frédéric G Buono

Org Lett· October 2005

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Controlled production of Camembert-type cheeses. Part I: Microbiological and physicochemical evolutions.
Marie-Noëlle Leclercq-Perlat, Frédéric Buono, Denis Lambert, Eric Latrille, Henry-Eric Spinnler

J Dairy Res· August 2004

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Physical and chemical rationalization for asymmetric amplification in autocatalytic reactions.
Frederic G Buono, Hiroshi Iwamura, Donna G Blackmond

Angew Chem Int Ed Engl· April 2004

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Kinetic evidence for a tetrameric transition state in the asymmetric autocatalytic alkylation of pyrimidyl aldehydes.
Frederic G Buono, Donna G Blackmond

J Am Chem Soc· July 2003

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Rationalization of anomalous nonlinear effects in the alkylation of substituted benzaldehydes.
Frederic Buono, Patrick J Walsh, Donna G Blackmond

J Am Chem Soc· November 2002

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