Publications by authors named "Fumin Fu"

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Lack of authentic atrial fibrillation in commonly used murine atrial fibrillation models.
Fumin Fu, Michael Pietropaolo, Lei Cui, Shilpa Pandit, Weiyan Li

PLoS One· February 2022

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Structure-Guided Design of Substituted Biphenyl Butanoic Acid Derivatives as Neprilysin Inhibitors.
Toshio Kawanami, Rajeshri G Karki, Emma Cody, Qian Liu, Guiqing Liang, Fumin Fu

ACS Med Chem Lett· February 2020

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Characterization and Prediction of Cardiovascular Effects of Fingolimod and Siponimod Using a Systems Pharmacology Modeling Approach.
Nelleke Snelder, Bart A Ploeger, Olivier Luttringer, Dean F Rigel, Randy L Webb, Fumin Fu

J Pharmacol Exp Ther· February 2017

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Small-molecule WNK inhibition regulates cardiovascular and renal function.
Ken Yamada, Hyi-Man Park, Dean F Rigel, Keith DiPetrillo, Erin J Whalen, Fumin Fu, Fupeng Ma

Nat Chem Biol· November 2016

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Discovery of N-[5-(6-Chloro-3-cyano-1-methyl-1H-indol-2-yl)-pyridin-3-ylmethyl]-ethanesulfonamide, a Cortisol-Sparing CYP11B2 Inhibitor that Lowers Aldosterone in Human Subjects.
Julien P N Papillon, Changgang Lou, Alok K Singh, Christopher M Adams, Gary M Ksander, Fumin Fu

J Med Chem· December 2015

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Structure-Activity Relationships, Pharmacokinetics, and in Vivo Activity of CYP11B2 and CYP11B1 Inhibitors.
Julien P N Papillon, Christopher M Adams, Qi-Ying Hu, Changgang Lou, Alok K Singh, Fumin Fu

J Med Chem· June 2015

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Aldosterone synthase inhibition: cardiorenal protection in animal disease models and translation of hormonal effects to human subjects.
Joël Ménard, Dean F Rigel, Catherine Watson, Arco Y Jeng, Fumin Fu

J Transl Med· December 2014

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Chronic measurement of left ventricular pressure in freely moving rats.
Ellyce Stehlin, Simon C Malpas, David M Budgett, Carolyn J Barrett, Daniel McCormick, Fumin Fu

J Appl Physiol (1985)· December 2013

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Discovery and in Vivo Evaluation of Potent Dual CYP11B2 (Aldosterone Synthase) and CYP11B1 Inhibitors.
Erik L Meredith, Gary Ksander, Lauren G Monovich, Julien P N Papillon, Qian Liu, Fumin Fu

ACS Med Chem Lett· December 2013

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Pharmacodynamic and pharmacokinetic characterization of the aldosterone synthase inhibitor FAD286 in two rodent models of hyperaldosteronism: comparison with the 11beta-hydroxylase inhibitor metyrapone.
Dean F Rigel, Fumin Fu, Michael Beil, Chii-Whei Hu, Guiqing Liang

J Pharmacol Exp Ther· July 2010

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Development of a combined heart and carotid artery transplant model to investigate the impact of acute rejection on cardiac allograft vasculopathy.
Behzad Soleimani, Fumin Fu, Philip Lake, Victor C Shi

J Heart Lung Transplant· April 2008

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Long-term islet graft survival in streptozotocin- and autoimmune-induced diabetes models by immunosuppressive and potential insulinotropic agent FTY720.
Fumin Fu, Shiling Hu, Jeffrey Deleo, Shu Li, Christine Hopf

Transplantation· May 2002

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T-cell depletion and graft survival induced by anti-human CD3 immunotoxins in human CD3epsilon transgenic mice.
Marla Weetall, Mary Ellen Digan, Ronald Hugo, Sheba Mathew, Christine Hopf, Fumin Fu

Transplantation· May 2002

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