Publications by authors named "Gad Abraham"

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Integrated clinical risk prediction of type 2 diabetes with a multifactorial polygenic risk score.
Scott C Ritchie, Henry J Taylor, Yujian Liang, Hasanga D Manikpurage, Lisa Pennells, Gad Abraham

medRxiv· September 2024

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Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity.
Mark K Bakker, Jos P Kanning, Gad Abraham, Amy E Martinsen, Bendik S Winsvold

Stroke· March 2023

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Prognostic Value of a Polygenic Risk Score for Coronary Heart Disease in Individuals Aged 70 Years and Older.
Johannes T Neumann, Moeen Riaz, Andrew Bakshi, Galina Polekhina, Le T P Thao, Gad Abraham

Circ Genom Precis Med· February 2022

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Integrative analysis of the plasma proteome and polygenic risk of cardiometabolic diseases.
Scott C Ritchie, Samuel A Lambert, Matthew Arnold, Shu Mei Teo, Sol Lim, Gad Abraham

Nat Metab· November 2021

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Predictive Performance of a Polygenic Risk Score for Incident Ischemic Stroke in a Healthy Older Population.
Johannes T Neumann, Moeen Riaz, Andrew Bakshi, Galina Polekhina, Le T P Thao, Gad Abraham

Stroke· August 2021

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Risk Prediction Using Polygenic Risk Scores for Prevention of Stroke and Other Cardiovascular Diseases.
Gad Abraham, Loes Rutten-Jacobs, Michael Inouye

Stroke· August 2021

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The Polygenic Score Catalog as an open database for reproducibility and systematic evaluation.
Samuel A Lambert, Laurent Gil, Simon Jupp, Scott C Ritchie, Yu Xu, Gad Abraham

Nat Genet· April 2021

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Polygenic risk scores in cardiovascular risk prediction: A cohort study and modelling analyses.
Luanluan Sun, Lisa Pennells, Stephen Kaptoge, Christopher P Nelson, Scott C Ritchie, Gad Abraham

PLoS Med· January 2021

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Genomic risk scores for juvenile idiopathic arthritis and its subtypes.
Rodrigo Cánovas, Joanna Cobb, Marta Brozynska, John Bowes, Yun R Li, Gad Abraham

Ann Rheum Dis· December 2020

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Elevated serum alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality.
Scott C Ritchie, Johannes Kettunen, Marta Brozynska, Artika P Nath, Aki S Havulinna, Gad Abraham

PLoS One· March 2020

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Author Correction: Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke.
Gad Abraham, Rainer Malik, Ekaterina Yonova-Doing, Agus Salim, Tingting Wang

Nat Commun· February 2020

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Multivariate Genome-wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy.
Artika P Nath, Scott C Ritchie, Nastasiya F Grinberg, Howard Ho-Fung Tang, Qin Qin Huang, Gad Abraham

Am J Hum Genet· December 2019

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Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke.
Gad Abraham, Rainer Malik, Ekaterina Yonova-Doing, Agus Salim, Tingting Wang

Nat Commun· December 2019

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Towards clinical utility of polygenic risk scores.
Samuel A Lambert, Gad Abraham, Michael Inouye

Hum Mol Genet· November 2019

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Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention.
Michael Inouye, Gad Abraham, Christopher P Nelson, Angela M Wood, Michael J Sweeting

J Am Coll Cardiol· October 2018

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Interactions within the MHC contribute to the genetic architecture of celiac disease.
Benjamin Goudey, Gad Abraham, Eder Kikianty, Qiao Wang, Dave Rawlinson

PLoS One· September 2017

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FlashPCA2: principal component analysis of Biobank-scale genotype datasets.
Gad Abraham, Yixuan Qiu, Michael Inouye

Bioinformatics· September 2017

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An interaction map of circulating metabolites, immune gene networks, and their genetic regulation.
Artika P Nath, Scott C Ritchie, Sean G Byars, Liam G Fearnley, Aki S Havulinna, Gad Abraham

Genome Biol· August 2017

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Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy.
Sean G Byars, Qin Qin Huang, Lesley-Ann Gray, Andrew Bakshi, Samuli Ripatti, Gad Abraham

PLoS Genet· June 2017

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Genomic prediction of coronary heart disease.
Gad Abraham, Aki S Havulinna, Oneil G Bhalala, Sean G Byars, Alysha M De Livera

Eur Heart J· November 2016

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A Scalable Permutation Approach Reveals Replication and Preservation Patterns of Network Modules in Large Datasets.
Scott C Ritchie, Stephen Watts, Liam G Fearnley, Kathryn E Holt, Gad Abraham

Cell Syst· July 2016

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The Biomarker GlycA Is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection.
Scott C Ritchie, Peter Würtz, Artika P Nath, Gad Abraham, Aki S Havulinna

Cell Syst· October 2015

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Genomic risk prediction of complex human disease and its clinical application.
Gad Abraham, Michael Inouye

Curr Opin Genet Dev· August 2015

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Genomic prediction of celiac disease targeting HLA-positive individuals.
Gad Abraham, Alexia Rohmer, Jason A Tye-Din, Michael Inouye

Genome Med· August 2015

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Towards a molecular systems model of coronary artery disease.
Gad Abraham, Oneil G Bhalala, Paul I W de Bakker, Samuli Ripatti, Michael Inouye

Curr Cardiol Rep· January 2015

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