Publications by authors named "Gael Roth"

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Real-world efficacy of immune checkpoint inhibitors in microsatellite unstable/mismatch repair-deficient biliary tract cancer: An AGEO study.
Iona Campo-Le-Brun, Emma Grapinet, Valerie Aurillac, Antoine Hollebecque, Pauline Parent, Gael Roth

Eur J Cancer· September 2025

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TFOX versus FOLFOX in first-line treatment of patients with advanced HER2-negative gastric or gastro-oesophageal junction adenocarcinoma (PRODIGE 51- FFCD-GASTFOX): an open-label, multicentre, randomised, phase 3 trial.
Aziz Zaanan, Olivier Bouché, Christelle de la Fouchardière, Karine Le Malicot, Simon Pernot, Gael Roth

Lancet Oncol· June 2025

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First-line chemotherapy with selective internal radiation therapy for intrahepatic cholangiocarcinoma: The French ACABi GERCOR PRONOBIL cohort.
Nicolas Adamus, Julien Edeline, Julie Henriques, Nadim Fares, Thierry Lecomte, Gaël S Roth

JHEP Rep· February 2025

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Tumor-associated macrophages confer resistance to chemotherapy (Trifluridine/Tipiracil) in digestive cancers by overexpressing thymidine phosphorylase.
Marie Malier, Marie-Hélène Laverriere, Maxime Henry, Malika Yakoubi, Pascale Bellaud, Gael S Roth

Cancer Lett· December 2024

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Metabolic reprogramming of hypoxic tumor-associated macrophages through CSF-1R targeting favors treatment efficiency in colorectal cancers.
Khaldoun Gharzeddine, Cristina Gonzalez Prieto, Marie Malier, Clara Hennot, Renata Grespan, Gael Roth

J Immunother Cancer· September 2024

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Biliary tract cancers: French national clinical practice guidelines for diagnosis, treatments and follow-up (TNCD, SNFGE, FFCD, UNICANCER, GERCOR, SFCD, SFED, AFEF, SFRO, SFP, SFR, ACABi, ACHBPT).
Gael S Roth, Loic Verlingue, Matthieu Sarabi, Jean-Frédéric Blanc, Emmanuel Boleslawski

Eur J Cancer· May 2024

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Completion pancreatectomy during pancreatoduodenectomy: A lifesaving solution in high-risk patients.
Antoine Ailhaud, Edouard Girard, Joey Fournier, Julio Abba, Emmanuel Devant, Gaël S Roth

World J Surg· May 2024

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Gemcitabine and Paclitaxel Versus Gemcitabine Alone After 5-Fluorouracil, Oxaliplatin, and Irinotecan in Metastatic Pancreatic Adenocarcinoma: A Randomized Phase III PRODIGE 65-UCGI 36-GEMPAX UNICANCER Study.
Christelle De La Fouchardière, David Malka, Claire Cropet, Sylvie Chabaud, Judith Raimbourg, Gaël S Roth

J Clin Oncol· March 2024

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Pemigatinib for patients with previously treated, locally advanced or metastatic cholangiocarcinoma harboring FGFR2 fusions or rearrangements: A joint analysis of the French PEMI-BIL and Italian PEMI-REAL cohort studies.
Alessandro Parisi, Blandine Delaunay, Giada Pinterpe, Antoine Hollebecque, Jean Frederic Blanc, Gael Roth

Eur J Cancer· March 2024

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Author Correction: Cytoskeleton remodeling induced by SMYD2 methyltransferase drives breast cancer metastasis.
Alexandre G Casanova, Gael S Roth, Simone Hausmann, Xiaoyin Lu, Ludivine J M Bischoff

Cell Discov· March 2024

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Ezurpimtrostat, A Palmitoyl-Protein Thioesterase-1 Inhibitor, Combined with PD-1 Inhibition Provides CD8 Lymphocyte Repopulation in Hepatocellular Carcinoma.
Eloïne Bestion, Madani Rachid, Annemilaï Tijeras-Raballand, Gael Roth, Thomas Decaens

Target Oncol· January 2024

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Radiological diagnosis of hepatocellular carcinoma does not preclude biopsy before treatment.
Bleuenn Brusset, Marion Jacquemin, Yann Teyssier, Gaël S Roth, Nathalie Sturm

JHEP Rep· January 2024

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Cytoskeleton remodeling induced by SMYD2 methyltransferase drives breast cancer metastasis.
Alexandre G Casanova, Gael S Roth, Simone Hausmann, Xiaoyin Lu, Ludivine J M Bischoff

Cell Discov· January 2024

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Cytoskeleton remodeling induced by SMYD2 methyltransferase drives breast cancer metastasis.
Alexandre G Casanova, Gael S Roth, Simone Hausmann, Xiaoyin Lu, Lucid Belmudes

bioRxiv· September 2023

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Discrepancies between dihydropyrimidine dehydrogenase phenotyping and genotyping: What are the explanatory factors?
Capucine Arrivé, Xavier Fonrose, Fabienne Thomas, Gaël Roth, Emmanuelle Jacquet

Br J Clin Pharmacol· August 2023

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Optimal treatment strategy after first-line induction therapy in advanced HER2-positive oeso-gastric adenocarcinoma-a retrospective, international, multicentric AGEO study.
Elisabeth S Bergen, Lorenzo Pilla, Edouard Auclin, Aysegül Ilhan-Mutlu, Gerald W Prager, Gael Roth

Gastric Cancer· May 2023

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Immunotherapy in hepatocellular carcinoma: How does underlying liver disease influence therapeutic strategy and outcomes?
Gael S Roth, François Villeret, Thomas Decaens, Philippe Merle, Pierre Nahon

Liver Int· March 2023

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Endovascular Lymphatic Decompression via Thoracic Duct Stent Placement for Refractory Ascites in Patients with Cirrhosis: A Pilot Study.
Julien Ghelfi, Bleuenn Brusset, Yann Teyssier, Christian Sengel, Teophile Gerster, Gael Roth

J Vasc Interv Radiol· February 2023

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Cholangiocarcinoma: what are the options in all comers and how has the advent of molecular profiling opened the way to personalised medicine ?
Gael S Roth, Cindy Neuzillet, Matthieu Sarabi, Julien Edeline, David Malka

Eur J Cancer· January 2023

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Quality of life of patients with solid malignancies at 3 months after unplanned admission in the intensive care unit: A prospective case-control study.
Anne-Claire Toffart, Wassila M'Sallaoui, Sophie Jerusalem, Alexandre Godon, Francois Bettega, Gael Roth

PLoS One· January 2023

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Effect of Novel AKT Inhibitor Vevorisertib as Single Agent and in Combination with Sorafenib on Hepatocellular Carcinoma in a Cirrhotic Rat Model.
Keerthi Kurma, Ayca Zeybek Kuyucu, Gaël S Roth, Nathalie Sturm, Marion Mercey-Ressejac

Int J Mol Sci· December 2022

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Structural and Socio-Spatial Determinants Influencing Care and Survival of Patients with a Pancreatic Adenocarcinoma: Results of the PANDAURA Cohort.
Gaël S Roth, Yohan Fayet, Sakina Benmameche-Medjahed, Françoise Ducimetière, Amandine Charreton

Cancers (Basel)· November 2022

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Evolution of Thoracic Duct Congestion after Portal Decompression by TIPS in Cirrhotic Patients.
Pauline Porret, Bleuenn Brusset, Alexandre Bellier, Ivan Bricault, Edouard Girard, Gael Roth

Cardiovasc Intervent Radiol· October 2022

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Impact of sarcopenia on tumor response and survival outcomes in patients with hepatocellular carcinoma treated by trans-arterial (chemo)-embolization.
Gael Roth, Yann Teyssier, Maxime Benhamou, Mélodie Abousalihac, Stefano Caruso

World J Gastroenterol· September 2022

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First-In-Human Effects of PPT1 Inhibition Using the Oral Treatment with GNS561/Ezurpimtrostat in Patients with Primary and Secondary Liver Cancers.
James J Harding, Ahmad Awada, Gael Roth, Thomas Decaens, Philippe Merle

Liver Cancer· June 2022

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