Publications by authors named "Gaetan Roy"

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Studies of the FBT family transporters in Leishmania infantum by gene deletion and protein localization.
Sophia Bigot, Amin Ahmed Ouameur, Gaétan Roy, Raouia Fakhfakh, Jean-François Ritt

Exp Parasitol· January 2025

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Decreased glutamate transport in acivicin resistant Leishmania tarentolae.
Gaétan Roy, Arijit Bhattacharya, Philippe Leprohon, Marc Ouellette

PLoS Negl Trop Dis· December 2021

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MRPA-independent mechanisms of antimony resistance in Leishmania infantum.
Noélie Douanne, Victoria Wagner, Gaetan Roy, Philippe Leprohon, Marc Ouellette

Int J Parasitol Drugs Drug Resist· August 2020

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Coupling chemical mutagenesis to next generation sequencing for the identification of drug resistance mutations in Leishmania.
Arijit Bhattacharya, Philippe Leprohon, Sophia Bigot, Prasad Kottayil Padmanabhan, Angana Mukherjee, Gaétan Roy

Nat Commun· December 2019

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High-throughput Cos-Seq screen with intracellular Leishmania infantum for the discovery of novel drug-resistance mechanisms.
Christopher Fernandez-Prada, Mansi Sharma, Marie Plourde, Eva Bresson, Gaétan Roy

Int J Parasitol Drugs Drug Resist· August 2018

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Growth arrested live-attenuated Leishmania infantum KHARON1 null mutants display cytokinesis defect and protective immunity in mice.
Ana Maria Murta Santi, Juliane Sousa Lanza, Luiza Guimarães Tunes, Jacqueline Araújo Fiuza, Gaétan Roy

Sci Rep· August 2018

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Different Mutations in a P-type ATPase Transporter in Leishmania Parasites are Associated with Cross-resistance to Two Leading Drugs by Distinct Mechanisms.
Christopher Fernandez-Prada, Isabel M Vincent, Marie-Christine Brotherton, Mathew Roberts, Gaétan Roy

PLoS Negl Trop Dis· December 2016

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Inactivation of the cytosolic and mitochondrial serine hydroxymethyl transferase genes in Leishmania major.
Gaétan Roy, Marc Ouellette

Mol Biochem Parasitol· December 2015

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Roles of Rad51 paralogs for promoting homologous recombination in Leishmania infantum.
Marie-Michelle Genois, Marie Plourde, Chantal Éthier, Gaétan Roy, Guy G Poirier

Nucleic Acids Res· March 2015

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Genome-wide stochastic adaptive DNA amplification at direct and inverted DNA repeats in the parasite Leishmania.
Jean-Michel Ubeda, Frédéric Raymond, Angana Mukherjee, Marie Plourde, Hélène Gingras, Gaétan Roy

PLoS Biol· May 2014

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Interactions between BRCA2 and RAD51 for promoting homologous recombination in Leishmania infantum.
Marie-Michelle Genois, Angana Mukherjee, Jean-Michel Ubeda, Rémi Buisson, Eric Paquet, Gaétan Roy

Nucleic Acids Res· August 2012

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Discovery of factors linked to antimony resistance in Leishmania panamensis through differential proteome analysis.
John Walker, Rafael Gongora, Juan-José Vasquez, Jolyne Drummelsmith, Richard Burchmore, Gaetan Roy

Mol Biochem Parasitol· June 2012

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Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic species.
Frédéric Raymond, Sébastien Boisvert, Gaétan Roy, Jean-François Ritt, Danielle Légaré

Nucleic Acids Res· February 2012

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Genetic polymorphisms and drug susceptibility in four isolates of Leishmania tropica obtained from Canadian soldiers returning from Afghanistan.
Marie Plourde, Adriano Coelho, Yoav Keynan, Oscar E Larios, Momar Ndao, Gaétan Roy

PLoS Negl Trop Dis· January 2012

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The gamma-glutamylcysteine synthetase gene of Leishmania is essential and involved in response to oxidants.
Angana Mukherjee, Gaétan Roy, Chantal Guimond, Marc Ouellette

Mol Microbiol· November 2009

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Down regulation of KMP-11 in Leishmania infantum axenic antimony resistant amastigotes as revealed by a proteomic screen.
Karima El Fadili, Jolyne Drummelsmith, Gaétan Roy, Armando Jardim, Marc Ouellette

Exp Parasitol· September 2009

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A protein of the leucine-rich repeats (LRRs) superfamily is implicated in antimony resistance in Leishmania infantum amastigotes.
Paul-André Genest, Anass Haimeur, Danielle Légaré, Denis Sereno, Gaétan Roy

Mol Biochem Parasitol· March 2008

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Modulation of gene expression in human macrophages treated with the anti-leishmania pentavalent antimonial drug sodium stibogluconate.
Karima El Fadili, Michaël Imbeault, Nadine Messier, Gaétan Roy, Benjamin Gourbal

Antimicrob Agents Chemother· February 2008

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Role of ABC transporter MRPA, gamma-glutamylcysteine synthetase and ornithine decarboxylase in natural antimony-resistant isolates of Leishmania donovani.
Angana Mukherjee, Prasad K Padmanabhan, Sushma Singh, Gaétan Roy, Isabelle Girard

J Antimicrob Chemother· February 2007

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Role of the ABC transporter MRPA (PGPA) in antimony resistance in Leishmania infantum axenic and intracellular amastigotes.
Karima El Fadili, Nadine Messier, Philippe Leprohon, Gaétan Roy, Chantal Guimond

Antimicrob Agents Chemother· May 2005

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Inactivation of the Leishmania tarentolae pterin transporter (BT1) and reductase (PTR1) genes leads to viable parasites with changes in folate metabolism and hypersensitivity to the antifolate methotrexate.
Amal El Fadili, Christoph Kündig, Gaétan Roy, Marc Ouellette

J Biol Chem· April 2004

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Antimony uptake systems in the protozoan parasite Leishmania and accumulation differences in antimony-resistant parasites.
Christian Brochu, Jingyu Wang, Gaétan Roy, Nadine Messier, Xiao-Yan Wang

Antimicrob Agents Chemother· October 2003

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Pterin transport and metabolism in Leishmania and related trypanosomatid parasites.
Marc Ouellette, Jolyne Drummelsmith, Amal El-Fadili, Christoph Kündig, Dave Richard, Gaétan Roy

Int J Parasitol· April 2002

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Reduced infectivity of a Leishmania donovani biopterin transporter genetic mutant and its use as an attenuated strain for vaccination.
Barbara Papadopoulou, Gaétan Roy, Marie Breton, Christoph Kündig, Carole Dumas

Infect Immun· January 2002

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