Publications by authors named "Ganesan Vaidyanathan"

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Effective treatment of human prostate carcinoma xenografts with Single-Dose PSMA-targeted [At]YF2.
Yutian Feng, Truc T Huynh, Yongxiang Zheng, Rebecca L Banks, Martin G Pomper, Ganesan Vaidyanathan

Eur J Nucl Med Mol Imaging· October 2025

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Enhancing the therapeutic index of [At]YF2 with iodo pseudo carrier: A simple strategy for reducing accumulation in kidneys, salivary and lacrimal glands.
Truc T Huynh, Yutian Feng, Rebecca L Banks, Ganesan Vaidyanathan, Michael R Zalutsky

Nucl Med Biol· September 2025

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Synthesis and preliminary evaluation of At-labeled inhibitors of prostate-specific membrane antigen for targeted alpha particle therapy of prostate cancer.
Ganesan Vaidyanathan, Ronnie C Mease, Il Minn, Jaeyeon Choi, Ying Chen

Nucl Med Biol· July 2024

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Labeling single domain antibody fragments with F using a novel residualizing prosthetic agent - N-succinimidyl 3-(1-(2-(2-(2-(2-[F]fluoroethoxy)ethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)-5-(guanidinomethyl)benzoate.
Zhengyuan Zhou, Darryl McDougald, Rebecca Meshaw, Irina Balyasnikova, Michael R Zalutsky, Ganesan Vaidyanathan

Nucl Med Biol· July 2024

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A third generation PSMA-targeted agent [At]YF2: Synthesis and in vivo evaluation.
Yutian Feng, Rebecca L Meshaw, Sean W Finch, Yongxiang Zheng, Il Minn, Ganesan Vaidyanathan

Nucl Med Biol· June 2024

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PSMA-reactive NB7 single domain antibody fragment: A potential scaffold for developing prostate cancer theranostics.
Truc T Huynh, Yutian Feng, Rebecca Meshaw, Xiao-Guang Zhao, Lior Rosenfeld, Ganesan Vaidyanathan

Nucl Med Biol· June 2024

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Effective Treatment of Human Breast Carcinoma Xenografts with Single-Dose At-Labeled Anti-HER2 Single-Domain Antibody Fragment.
Yutian Feng, Rebecca Meshaw, Xiao-Guang Zhao, Stephen Jannetti, Ganesan Vaidyanathan

J Nucl Med· January 2023

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Site-Specific Radiohalogenation of a HER2-Targeted Single-Domain Antibody Fragment Using a Novel Residualizing Prosthetic Agent.
Yutian Feng, Samantha M Sarrett, Rebecca L Meshaw, Ganesan Vaidyanathan, Mike A Cornejo

J Med Chem· November 2022

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Preclinical Development of [211At]meta- astatobenzylguanidine ([211At]MABG) as an Alpha Particle Radiopharmaceutical Therapy for Neuroblastoma.
Vandana Batra, Minu Samanta, Mehran Makvandi, David Groff, Paul Martorano, Ganesan Vaidyanathan

Clin Cancer Res· September 2022

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Low-level whole-brain radiation enhances theranostic potential of single-domain antibody fragments for human epidermal growth factor receptor type 2 (HER2)-positive brain metastases.
Daniele Procissi, Stephen A Jannetti, Markella Zannikou, Zhengyuan Zhou, Darryl McDougald, Ganesan Vaidyanathan

Neurooncol Adv· August 2022

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An Improved At-Labeled Agent for PSMA-Targeted α-Therapy.
Ronnie C Mease, Choong Mo Kang, Vivek Kumar, Sangeeta Ray Banerjee, Il Minn, Ganesan Vaidyanathan

J Nucl Med· February 2022

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Evaluation of an I-labeled HER2-specific single domain antibody fragment for the radiopharmaceutical therapy of HER2-expressing cancers.
Yutian Feng, Rebecca Meshaw, Darryl McDougald, Zhengyuan Zhou, Xiao-Guang Zhao, Ganesan Vaidyanathan

Sci Rep· February 2022

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Site-Specific and Residualizing Linker for F Labeling with Enhanced Renal Clearance: Application to an Anti-HER2 Single-Domain Antibody Fragment.
Zhengyuan Zhou, Rebecca Meshaw, Michael R Zalutsky, Ganesan Vaidyanathan

J Nucl Med· November 2021

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Gold Nanostars: A Novel Platform for Developing At-Labeled Agents for Targeted Alpha-Particle Therapy.
Yang Liu, Zhengyuan Zhou, Yutian Feng, Xiao-Guang Zhao, Ganesan Vaidyanathan

Int J Nanomedicine· November 2021

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Correction to: Switch-on effect on conformation-specific arylamine-DNA adduct by cyclometalated Ir(III) complexes.
David Dayanidhi Paul Elisa, Vaidyanathan Vaidyanathan Ganesan

J Biol Inorg Chem· September 2021

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Correction: Selective recognition of DNA defects by cyclometalated Ir(iii) complexes.
David Paul Elisa Dayanidhi, Rosaria Pinky Malapati, Vaidyanathan Vaidyanathan Ganesan

Dalton Trans· August 2021

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Site-specific radioiodination of an anti-HER2 single domain antibody fragment with a residualizing prosthetic agent.
Yutian Feng, Zhengyuan Zhou, Darryl McDougald, Rebecca L Meshaw, Ganesan Vaidyanathan

Nucl Med Biol· January 2021

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Labeling Monoclonal Antibody with α-emitting At at High Activity Levels via a Tin Precursor.
Ganesan Vaidyanathan, Oscar R Pozzi, Jaeyeon Choi, Xiao-Guang Zhao, Shawn Murphy

Cancer Biother Radiopharm· September 2020

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Labeling a TCO-functionalized single domain antibody fragment with F via inverse electron demand Diels Alder cycloaddition using a fluoronicotinyl moiety-bearing tetrazine derivative.
Zhengyuan Zhou, Michael R Zalutsky, Ganesan Vaidyanathan

Bioorg Med Chem· September 2020

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Observations on the Effects of Residualization and Dehalogenation on the Utility of -Succinimidyl Ester Acylation Agents for Radioiodination of the Internalizing Antibody Trastuzumab.
Satish K Chitneni, Eftychia Koumarianou, Ganesan Vaidyanathan, Michael R Zalutsky

Molecules· October 2019

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Non-invasive sensitive brain tumor detection using dual-modality bioimaging nanoprobe.
Yang Liu, Austin B Carpenter, Christopher J Pirozzi, Hsiangkuo Yuan, Matthew S Waitkus, Ganesan Vaidyanathan

Nanotechnology· July 2019

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Brush border enzyme-cleavable linkers: Evaluation for reducing renal uptake of radiolabeled prostate-specific membrane antigen inhibitors.
Ganesan Vaidyanathan, Choong Mo Kang, Darryl McDougald, Il Minn, Mary Brummet

Nucl Med Biol· February 2019

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Labeling Single Domain Antibody Fragments with Fluorine-18 Using 2,3,5,6-Tetrafluorophenyl 6-[F]Fluoronicotinate Resulting in High Tumor-to-Kidney Ratios.
Zhengyuan Zhou, Darryl McDougald, Nick Devoogdt, Michael R Zalutsky, Ganesan Vaidyanathan

Mol Pharm· January 2019

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An Efficient Method for Labeling Single Domain Antibody Fragments with F Using Tetrazine- Trans-Cyclooctene Ligation and a Renal Brush Border Enzyme-Cleavable Linker.
Zhengyuan Zhou, Nick Devoogdt, Michael R Zalutsky, Ganesan Vaidyanathan

Bioconjug Chem· December 2018

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Elastic compliance of fibrillar assemblies in type I collagen.
Vaidyanathan Vaidyanathan Ganesan, Madhumitha Dhanasekaran, Nandhini Thangavel, Aruna Dhathathreyan

Biophys Chem· September 2018

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