Publications by authors named "Gary Chinigo"

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Discovery of PF-07054894, a Potent Squaramide-Based CCR6 Antagonist Displaying High CXCR2 Selectivity.
Mark E Schnute, Huixian Wu, John I Trujillo, Wei Li, David Jonathan Wasilko, Gary M Chinigo

J Med Chem· October 2025

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Peptidylarginine Deiminase (PAD) Inhibitor Optimization through Displacement of a Trapped Water Molecule.
Mark E Schnute, Gary M Chinigo, Kentaro Futatsugi, Masaya Yamaguchi, Scott W Bagley

ACS Med Chem Lett· August 2025

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Conformational Role of Methyl in the Potency of Cyclohexane-Substituted Squaramide CCR6 Antagonists.
Brian S Gerstenberger, Ray Unwalla, Kathleen A Farley, Philippe Nuhant, Vincent M Lombardo, Gary M Chinigo

J Med Chem· February 2025

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Structural basis for CCR6 modulation by allosteric antagonists.
David Jonathan Wasilko, Brian S Gerstenberger, Kathleen A Farley, Wei Li, Jennifer Alley, Gary Chinigo

Nat Commun· August 2024

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One-Pot Synthesis of Sulfonamides from Unactivated Acids and Amines via Aromatic Decarboxylative Halosulfonylation.
P Scott Pedersen, David C Blakemore, Gary M Chinigo, Thomas Knauber, David W C MacMillan

J Am Chem Soc· October 2023

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Early Clinical Development of Lufotrelvir as a Potential Therapy for COVID-19.
Christophe Allais, David Bernhardson, Adam R Brown, Gary M Chinigo, Jean-Nicolas Desrosiers

Org Process Res Dev· February 2023

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Decarbonylative Pd-Catalyzed Suzuki Cross-Coupling for the Synthesis of Structurally Diverse Heterobiaryls.
Alejandro Cervantes-Reyes, Aaron C Smith, Gary M Chinigo, David C Blakemore, Michal Szostak

Org Lett· March 2022

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Design and tests of prospective property predictions for novel antimalarial 2-aminopropylaminoquinolones.
Robert D Clark, Denise N Morris, Gary Chinigo, Michael S Lawless, Jacques Prudhomme

J Comput Aided Mol Des· November 2020

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Visible-Light-Initiated Manganese Catalysis for C-H Alkylation of Heteroarenes: Applications and Mechanistic Studies.
Philippe Nuhant, Martins S Oderinde, Julien Genovino, Antoine Juneau, Yohann Gagné, Gary M Chinigo

Angew Chem Int Ed Engl· November 2017

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Towards the synthesis of massadine: a unified strategy for the stereoselective synthesis of the carbocyclic C,D-ring subunit.
Alexander Breder, Gary M Chinigo, Andrew W Waltman, Erick M Carreira

Chemistry· October 2011

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Ugi-4-component reaction enabling rapid access to the core fragment of massadine.
Gary M Chinigo, Alexander Breder, Erick M Carreira

Org Lett· January 2011

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Enantioselective synthesis of the carbocyclic D-ring subunit of massadine.
Alexander Breder, Gary M Chinigo, Andrew W Waltman, Erick M Carreira

Angew Chem Int Ed Engl· December 2008

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Asymmetric synthesis of 2,3-dihydro-2-arylquinazolin-4-ones: methodology and application to a potent fluorescent tubulin inhibitor with anticancer activity.
Gary M Chinigo, Mikell Paige, Scott Grindrod, Ernest Hamel, Sivanesan Dakshanamurthy

J Med Chem· August 2008

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Tumor-targeting nanodelivery enhances the anticancer activity of a novel quinazolinone analogue.
Sung Hee Hwang, Antonina Rait, Kathleen F Pirollo, Qi Zhou, Venkata Mahidhar Yenugonda, Gary M Chinigo

Mol Cancer Ther· March 2008

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