Publications by authors named "Gary P Sims"

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Oxidised IL-33 drives COPD epithelial pathogenesis ST2-independent RAGE/EGFR signalling complex.
Sam Strickson, Kirsty F Houslay, Victor A Negri, Yoichiro Ohne, Tomas Ottosson, Gary P Sims

Eur Respir J· September 2023

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Characterization of Citrullination Sites in Neutrophils and Mast Cells Activated by Ionomycin via Integration of Mass Spectrometry and Machine Learning.
Raghothama Chaerkady, Yebin Zhou, Jared A Delmar, Shao Huan Samuel Weng, Junmin Wang, Dorothy Sims, Gary P Sims

J Proteome Res· June 2021

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Immune Complex-Driven Generation of Human Macrophages with Anti-Inflammatory and Growth-Promoting Activity.
Elizabeth Dalby, Stephen M Christensen, Jingya Wang, Kajal Hamidzadeh, Prabha Chandrasekaran, Gary P Sims

J Immunol· July 2020

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LOX-1: A potential driver of cardiovascular risk in SLE patients.
Divya Sagar, Ranjitha Gaddipati, Emily L Ongstad, Nicholas Bhagroo, Ling-Ling An, Gary P Sims

PLoS One· June 2020

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Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal.
Mattias N D Svensson, Martina Zoccheddu, Shen Yang, Gyrid Nygaard, Christian Secchi, Gary P Sims

Sci Adv· June 2020

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Perspective on Protein Arginine Deiminase Activity-Bicarbonate Is a pH-Independent Regulator of Citrullination.
Yebin Zhou, Nanette Mittereder, Gary P Sims

Front Immunol· February 2019

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Humanised effector-null FcγRIIA antibody inhibits immune complex-mediated proinflammatory responses.
Bo Chen, Katherine A Vousden, Brian Naiman, Sean Turman, Hong Sun, Gary P Sims

Ann Rheum Dis· February 2019

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Evidence for a direct link between PAD4-mediated citrullination and the oxidative burst in human neutrophils.
Yebin Zhou, Ling-Ling An, Raghothama Chaerkady, Nanette Mittereder, Lori Clarke, Gary P Sims

Sci Rep· October 2018

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Characterisation of anifrolumab, a fully human anti-interferon receptor antagonist antibody for the treatment of systemic lupus erythematosus.
Jeffrey M Riggs, Richard N Hanna, Bhargavi Rajan, Kamelia Zerrouki, Jodi L Karnell, Gary P Sims

Lupus Sci Med· April 2018

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Affinity maturation shapes the function of agonistic antibodies to peptidylarginine deiminase type 4 in rheumatoid arthritis.
Jing Shi, Erika Darrah, Gary P Sims, Tomas Mustelin, Kevon Sampson

Ann Rheum Dis· January 2018

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Spontaneous Secretion of the Citrullination Enzyme PAD2 and Cell Surface Exposure of PAD4 by Neutrophils.
Yebin Zhou, Bo Chen, Nanette Mittereder, Raghothama Chaerkady, Martin Strain, Gary P Sims

Front Immunol· September 2017

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Aging and Systemic Lupus Erythematosus - Immunosenescence and Beyond.
Lucas Laurens van den Hoogen, Gary Patrick Sims, Joel Adrianus Gijsbert van Roon, Ruth Dorothea Elisabeth Fritsch-Stork

Curr Aging Sci· August 2016

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Characterization of the Hypercitrullination Reaction in Human Neutrophils and Other Leukocytes.
Yebin Zhou, Tiziana Di Pucchio, Gary P Sims, Nanette Mittereder, Tomas Mustelin

Mediators Inflamm· February 2016

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S100A9 induced inflammatory responses are mediated by distinct damage associated molecular patterns (DAMP) receptors in vitro and in vivo.
Bo Chen, Allison L Miller, Marlon Rebelatto, Yambasu Brewah, Daniel C Rowe, Gary P Sims

PLoS One· December 2015

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RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.
Cherilyn M Sirois, Tengchuan Jin, Allison L Miller, Damien Bertheloot, Hirotaka Nakamura, Gary P Sims

J Exp Med· October 2013

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RAGE inhibits human respiratory syncytial virus syncytium formation by interfering with F-protein function.
Jane Tian, Kelly Huang, Subramaniam Krishnan, Catherine Svabek, Daniel C Rowe, Gary P Sims

J Gen Virol· August 2013

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Opposing roles of membrane and soluble forms of the receptor for advanced glycation end products in primary respiratory syncytial virus infection.
Allison L Miller, Gary P Sims, Yambasu A Brewah, Marlon C Rebelatto, Jennifer Kearley

J Infect Dis· April 2012

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A glycoengineered anti-CD19 antibody with potent antibody-dependent cellular cytotoxicity activity in vitro and lymphoma growth inhibition in vivo.
Elizabeth Ward, Nanette Mittereder, Ellen Kuta, Gary P Sims, Michael A Bowen

Br J Haematol· November 2011

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Isolation of human B cell populations.
Guido Heine, Gary P Sims, Margitta Worm, Peter E Lipsky, Andreas Radbruch

Curr Protoc Immunol· August 2011

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Emerging small molecule and biological therapeutic approaches for the treatment of autoimmunity.
Andrew J Leishman, Gary P Sims, Matthew Sleeman, Martin Braddock

Expert Opin Investig Drugs· January 2011

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B-cell depletion in vitro and in vivo with an afucosylated anti-CD19 antibody.
Ronald Herbst, Yue Wang, Sandra Gallagher, Nanette Mittereder, Ellen Kuta, Gary P Sims

J Pharmacol Exp Ther· October 2010

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Expression of high-mobility group box 1 and of receptor for advanced glycation end products in chronic obstructive pulmonary disease.
Nassima Ferhani, Séverine Letuve, Alexander Kozhich, Olivier Thibaudeau, Martine Grandsaigne, Gary P Sims

Am J Respir Crit Care Med· May 2010

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HMGB1 and RAGE in inflammation and cancer.
Gary P Sims, Daniel C Rowe, Svend T Rietdijk, Ronald Herbst, Anthony J Coyle

Annu Rev Immunol· May 2010

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Synovial fibroblasts self-direct multicellular lining architecture and synthetic function in three-dimensional organ culture.
Hans P Kiener, Gerald F M Watts, Yajun Cui, John Wright, Thomas S Thornhill, Gary P Sims

Arthritis Rheum· March 2010

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Innate immune signals modulate antiviral and polyreactive antibody responses during severe respiratory syncytial virus infection.
Jennifer L Reed, Timothy P Welliver, Gary P Sims, Luann McKinney, Luis Velozo

J Infect Dis· April 2009

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