Publications by authors named "Geert Berx"

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Development and validation of a high-throughput screening pipeline of compound libraries to target EMT.
Sven Jonckheere, Joachim Taminau, Jamie Adams, Jef Haerinck, Jordy De Coninck, Geert Berx

Cell Death Differ· November 2025

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EMT-associated bias in the Parsortix® system observed with pancreatic cancer cell lines.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Geert Berx

Mol Oncol· November 2025

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EMT and cancer: what clinicians should know.
Erik W Thompson, Andrew D Redfern, Simone Brabletz, Geert Berx, Veenoo Agarwal

Nat Rev Clin Oncol· October 2025

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A dual role for PSIP1/LEDGF in T cell acute lymphoblastic leukemia.
Lisa Demoen, Filip Matthijssens, Lindy Reunes, Bruno Palhais, Béatrice Lintermans, Geert Berx

Sci Adv· November 2024

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Colibactin-driven colon cancer requires adhesin-mediated epithelial binding.
Maude Jans, Magdalena Kolata, Gillian Blancke, Aline D'Hondt, Claudia Gräf, Geert Berx

Nature· November 2024

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ZEB2 drives intra-tumor heterogeneity and skin squamous cell carcinoma formation with distinct EMP transition states.
Jeroen Verstappe, Nicolas Skrypek, Jordy De Coninck, Bieke Soen, Joachim Taminau, Geert Berx

iScience· November 2024

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Identification and validation of extracellular vesicle reference genes for the normalization of RT-qPCR data.
Cláudio Pinheiro, Niké Guilbert, Lien Lippens, Quentin Roux, Robin Boiy, Geert Berx

J Extracell Vesicles· April 2024

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Laser-induced vapor nanobubbles for B16-F10 melanoma cell killing and intracellular delivery of chemotherapeutics.
Jana Ramon, Yanou Engelen, Herlinde De Keersmaecker, Ilia Goemaere, Deep Punj, Geert Berx

J Control Release· January 2024

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The epithelial-mesenchymal plasticity landscape: principles of design and mechanisms of regulation.
Jef Haerinck, Steven Goossens, Geert Berx

Nat Rev Genet· September 2023

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Colibactin-induced genotoxicity and colorectal cancer exacerbation critically depends on adhesin-mediated epithelial binding.
Maude Jans, Magdalena Kolata, Gillian Blancke, Maarten Ciers, Anders B Dohlman, Geert Berx

bioRxiv· August 2023

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A role for partial epithelial-to-mesenchymal transition in enabling stemness in homeostasis and cancer.
Jeroen Verstappe, Geert Berx

Semin Cancer Biol· May 2023

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Distinct Transcriptional Programs in Ascitic and Solid Cancer Cells Induce Different Responses to Chemotherapy in High-Grade Serous Ovarian Cancer.
Nele Loret, Niels Vandamme, Jordy De Coninck, Joachim Taminau, Kato De Clercq, Geert Berx

Mol Cancer Res· October 2022

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Myb drives B-cell neoplasms and myeloid malignancies in vivo.
Tim Pieters, André Almeida, Sara T'Sas, Kelly Lemeire, Tino Hochepied, Geert Berx

Blood Adv· May 2022

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MLKL deficiency in BrafPten melanoma model results in a modest delay of nevi development and reduced lymph node dissemination in male mice.
Sofie Martens, Nozomi Takahashi, Gillian Blancke, Niels Vandamme, Hanne Verschuere, Geert Berx

Cell Death Dis· April 2022

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Endothelial Zeb2 preserves the hepatic angioarchitecture and protects against liver fibrosis.
Willeke de Haan, Wouter Dheedene, Katerina Apelt, Sofiane Décombas-Deschamps, Stefan Vinckier, Geert Berx

Cardiovasc Res· March 2022

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Executioner caspases 3 and 7 are dispensable for intestinal epithelium turnover and homeostasis at steady state.
Farzaneh Ghazavi, Jelle Huysentruyt, Jordy De Coninck, Stephanie Kourula, Sofie Martens, Geert Berx

Proc Natl Acad Sci U S A· February 2022

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Coordinate control of basal epithelial cell fate and stem cell maintenance by core EMT transcription factor Zeb1.
Yingying Han, Alvaro Villarreal-Ponce, Guadalupe Gutierrez, Quy Nguyen, Peng Sun, Geert Berx

Cell Rep· January 2022

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Author Correction: Guidelines and definitions for research on epithelial-mesenchymal transition.
Jing Yang, Parker Antin, Geert Berx, Cédric Blanpain, Thomas Brabletz

Nat Rev Mol Cell Biol· December 2021

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Partial EMT takes the lead in cancer metastasis.
Jef Haerinck, Geert Berx

Dev Cell· December 2021

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XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells.
Adam Wahida, Madeleine Müller, Andreas Hiergeist, Bastian Popper, Katja Steiger, Geert Berx

Sci Immunol· November 2021

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Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice.
Tim Pieters, Sara T'Sas, Stijn Vanhee, André Almeida, Yasmine Driege, Geert Berx

J Exp Med· October 2021

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Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity.
Jueqiong Wang, Carlos Farkas, Aissa Benyoucef, Catherine Carmichael, Katharina Haigh, Geert Berx

PLoS Biol· September 2021

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The ZEB2-dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer.
Rahul Sreekumar, Hajir Al-Saihati, Muhammad Emaduddin, Karwan Moutasim, Massimiliano Mellone, Geert Berx

Mol Oncol· August 2021

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The EMT transcription factor ZEB1 blocks osteoblastic differentiation in bone development and osteosarcoma.
Manuel Ruh, Marc P Stemmler, Isabell Frisch, Kathrin Fuchs, Ruthger van Roey, Geert Berx

J Pathol· June 2021

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Pancreas morphogenesis and homeostasis depends on tightly regulated Zeb1 levels in epithelial cells.
María Lasierra Losada, Melissa Pauler, Niels Vandamme, Steven Goossens, Geert Berx

Cell Death Discov· June 2021

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