Publications by authors named "Simone Brabletz"

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EMT and cancer: what clinicians should know.
Erik W Thompson, Andrew D Redfern, Simone Brabletz, Geert Berx, Veenoo Agarwal, Thomas Brabletz

Nat Rev Clin Oncol· October 2025

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Macrophages foster anti-tumor immunity by ZEB1-dependent cytotoxic T cell chemoattraction.
Kathrin Fuchs, Elisabetta D'Avanzo, Isabell Armstark, Ruthger van Roey, Ana Clavel Ezquerra, Simone Brabletz, Thomas Brabletz

Commun Biol· July 2025

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Ferroptosis in health and disease.
Carsten Berndt, Hamed Alborzinia, Vera Skafar Amen, Scott Ayton, Uladzimir Barayeu, Simone Brabletz, Thomas Brabletz

Redox Biol· September 2024

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Zeb1 mediates EMT/plasticity-associated ferroptosis sensitivity in cancer cells by regulating lipogenic enzyme expression and phospholipid composition.
Annemarie Schwab, Zhigang Rao, Jie Zhang, André Gollowitzer, Katharina Siebenkäs, Simone Brabletz, Thomas Brabletz

Nat Cell Biol· September 2024

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ZEB1-mediated fibroblast polarization controls inflammation and sensitivity to immunotherapy in colorectal cancer.
Constantin Menche, Harald Schuhwerk, Isabell Armstark, Pooja Gupta, Kathrin Fuchs, Simone Brabletz, Thomas Brabletz

EMBO Rep· August 2024

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ZEB1 Inhibits LHβ Subunit Transcription When Overexpressed, but Is Dispensable for LH Synthesis in Mice.
Hailey Schultz, Xiang Zhou, Carlos Agustín Isidro Alonso, Luisina Ongaro, Yeu-Farn Lin, Thomas Brabletz, Simone Brabletz

Endocrinology· August 2024

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Zeb1 maintains long-term adult hematopoietic stem cell function and extramedullary hematopoiesis.
Alhomidi Almotiri, Ali Abdelfattah, Elis Storch, Marc P Stemmler, Simone Brabletz, Thomas Brabletz

Exp Hematol· June 2024

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Epithelial-mesenchymal transition in the lacrimal gland morphogenesis, damage and repair.
Swati Singh, Simone Brabletz, Philipp Arnold, Martin Schicht, Friedrich Paulsen

Ocul Surf· July 2023

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A Zeb1/MtCK1 metabolic axis controls osteoclast activation and skeletal remodeling.
Lingxin Zhu, Yi Tang, Xiao-Yan Li, Samuel A Kerk, Costas A Lyssiotis, Simone Brabletz, Thomas Brabletz

EMBO J· April 2023

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The EMT transcription factor ZEB1 governs a fitness-promoting but vulnerable DNA replication stress response.
Harald Schuhwerk, Julia Kleemann, Pooja Gupta, Ruthger van Roey, Isabell Armstark, Simone Brabletz, Thomas Brabletz

Cell Rep· December 2022

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Dynamic EMT: a multi-tool for tumor progression.
Simone Brabletz, Harald Schuhwerk, Thomas Brabletz, Marc P Stemmler

EMBO J· September 2021

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Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity.
Jueqiong Wang, Carlos Farkas, Aissa Benyoucef, Catherine Carmichael, Katharina Haigh, Simone Brabletz, Thomas Brabletz

PLoS Biol· September 2021

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The transcription factor ZEB1 regulates stem cell self-renewal and cell fate in the adult hippocampus.
Bhavana Gupta, Adam C Errington, Ana Jimenez-Pascual, Vasileios Eftychidis, Simone Brabletz, Thomas Brabletz

Cell Rep· August 2021

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Cytomegalovirus subverts macrophage identity.
Sebastian Baasch, Piero Giansanti, Julia Kolter, André Riedl, Aaron James Forde, Simone Brabletz, Thomas Brabletz

Cell· July 2021

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Immunohistological Study of Palpebral Lobe of the Lacrimal Gland in Severe Dry Eyes Secondary to Stevens-Johnson Syndrome.
Swati Singh, Mohammad Javed Ali, Vikas Mittal, Simone Brabletz, Friedrich Paulsen

Curr Eye Res· June 2021

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The EMT transcription factor ZEB1 blocks osteoblastic differentiation in bone development and osteosarcoma.
Manuel Ruh, Marc P Stemmler, Isabell Frisch, Kathrin Fuchs, Ruthger van Roey, Thomas Brabletz, Simone Brabletz

J Pathol· June 2021

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Pancreas morphogenesis and homeostasis depends on tightly regulated Zeb1 levels in epithelial cells.
María Lasierra Losada, Melissa Pauler, Niels Vandamme, Steven Goossens, Geert Berx, Simone Brabletz, Thomas Brabletz

Cell Death Discov· June 2021

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Zeb1 modulates hematopoietic stem cell fates required for suppressing acute myeloid leukemia.
Alhomidi Almotiri, Hamed Alzahrani, Juan Bautista Menendez-Gonzalez, Ali Abdelfattah, Badi Alotaibi, Simone Brabletz, Thomas Brabletz

J Clin Invest· January 2021

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Genome-wide cooperation of EMT transcription factor ZEB1 with YAP and AP-1 in breast cancer.
Nora Feldker, Fulvia Ferrazzi, Harald Schuhwerk, Sebastian A Widholz, Kerstin Guenther, Thomas Brabletz, Simone Brabletz

EMBO J· September 2020

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Inactivation of in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure.
Marina R Carpinelli, Michael E de Vries, Alana Auden, Tariq Butt, Zihao Deng, Simone Brabletz, Thomas Brabletz

Dis Model Mech· March 2020

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An Ovol2-Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation.
Daniel Haensel, Peng Sun, Adam L MacLean, Xianghui Ma, Yuan Zhou, Simone Brabletz, Thomas Brabletz

EMBO Rep· January 2019

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Non-redundant functions of EMT transcription factors.
Marc P Stemmler, Rebecca L Eccles, Simone Brabletz, Thomas Brabletz

Nat Cell Biol· January 2019

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Road to perdition: Zeb1-dependent and -independent ways to metastasis.
Simone Brabletz, Thomas Brabletz, Marc P Stemmler

Cell Cycle· October 2017

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The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer.
Angela M Krebs, Julia Mitschke, María Lasierra Losada, Otto Schmalhofer, Melanie Boerries, Simone Brabletz, Thomas Brabletz

Nat Cell Biol· May 2017

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Generation and characterization of mice for conditional inactivation of Zeb1.
Simone Brabletz, María Lasierra Losada, Otto Schmalhofer, Julia Mitschke, Angela Krebs, Thomas Brabletz

Genesis· April 2017

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