Publications by authors named "Gene Colice"

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Population Pharmacokinetic Modeling and Exposure-Efficacy and Body Weight-Response Analyses for Tezepelumab in Patients With Severe, Uncontrolled Asthma.
Yanan Zheng, Lubna Abuqayyas, Angelica Quartino, Ye Guan, Yuying Gao, Gene Colice

J Clin Pharmacol· August 2024

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Effect of Tezepelumab on the Humoral Immune Response to Seasonal Quadrivalent Influenza Vaccination in Patients with Moderate to Severe Asthma: The Phase 3b VECTOR Study.
Jeremy Cole, Iwona Cąpała-Szczurko, Stephanie Roseti, Claudia Chen, Scott Caveney, Gene Colice

Pulm Ther· March 2024

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Tezepelumab reduces exacerbations across all seasons in patients with severe, uncontrolled asthma (NAVIGATOR).
Ian D Pavord, Flavia C L Hoyte, Andrew W Lindsley, Christopher S Ambrose, Joseph D Spahn, Gene Colice

Ann Allergy Asthma Immunol· November 2023

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Effect of Tezepelumab on Lung Function in Patients With Severe, Uncontrolled Asthma in the Phase 3 NAVIGATOR Study.
Andrew Menzies-Gow, Christopher S Ambrose, Gene Colice, Gillian Hunter, Bill Cook

Adv Ther· November 2023

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Tezepelumab for the treatment of severe asthma: a plain language summary of the PATHWAY and NAVIGATOR studies.
Jonathan Corren, Andrew Menzies-Gow, Johan Bimmel, Anthony McGuinness, Gun Almqvist, Gene Colice

Immunotherapy· November 2023

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Tezepelumab and Mucus Plugs in Patients with Moderate-to-Severe Asthma.
Lars H Nordenmark, Åsa Hellqvist, Claire Emson, Sarah Diver, Celeste Porsbjerg, Gene Colice

NEJM Evid· October 2023

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Effect of tezepelumab on healthcare utilization in patients with severe, uncontrolled asthma: The NAVIGATOR study.
Andrew Menzies-Gow, Arnaud Bourdin, Geoffrey Chupp, Elliot Israel, Åsa Hellqvist, Gene Colice

Ann Allergy Asthma Immunol· September 2023

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Efficacy of Tezepelumab in Severe, Uncontrolled Asthma: Pooled Analysis of the PATHWAY and NAVIGATOR Clinical Trials.
Jonathan Corren, Andrew Menzies-Gow, Geoffrey Chupp, Elliot Israel, Stephanie Korn, Gene Colice

Am J Respir Crit Care Med· July 2023

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Long-term safety and efficacy of tezepelumab in people with severe, uncontrolled asthma (DESTINATION): a randomised, placebo-controlled extension study.
Andrew Menzies-Gow, Michael E Wechsler, Christopher E Brightling, Stephanie Korn, Jonathan Corren, Gene Colice

Lancet Respir Med· May 2023

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Efficacy of tezepelumab in patients with evidence of severe allergic asthma: Results from the phase 3 NAVIGATOR study.
Jonathan Corren, Christopher S Ambrose, Janet M Griffiths, Åsa Hellqvist, Andrew W Lindsley, Gene Colice

Clin Exp Allergy· April 2023

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One-year safety and tolerability of tezepelumab in Japanese patients with severe uncontrolled asthma: results of the NOZOMI study.
Masaharu Shinkai, Motohiro Ebisawa, Yasushi Fukushima, Satomi Takeuchi, Hiroshi Okada, Gene Colice

J Asthma· March 2023

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Efficacy and safety of tezepelumab in patients with uncontrolled disease while receiving maintenance therapy for moderate or severe asthma.
Jonathan Corren, Michael E Wechsler, Geoffrey Chupp, Stephanie L Roseti, Åsa Hellqvist, Gene Colice

J Allergy Clin Immunol Pract· March 2023

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Efficacy and safety of tezepelumab in patients recruited in Japan who participated in the phase 3 NAVIGATOR study.
Tamotsu Ishizuka, Andrew Menzies-Gow, Hiroshi Okada, Yasushi Fukushima, Nobuya Hayashi, Gene Colice

Allergol Int· January 2023

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Feno differentiates epithelial gene expression clusters: Exploratory analysis from the MESOS randomized controlled trial.
Sarah Diver, Sriram Sridhar, Latifa C Khalfaoui, Richard J Russell, Claire Emson, Gene Colice

J Allergy Clin Immunol· October 2022

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Evaluation of the oral corticosteroid-sparing effect of tezepelumab in adults with oral corticosteroid-dependent asthma (SOURCE): a randomised, placebo-controlled, phase 3 study.
Michael E Wechsler, Andrew Menzies-Gow, Christopher E Brightling, Piotr Kuna, Stephanie Korn, Gene Colice

Lancet Respir Med· July 2022

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Baseline type 2 biomarker levels and response to tezepelumab in severe asthma.
Jonathan Corren, Tuyet-Hang Pham, Esther Garcia Gil, Kinga Sałapa, Pin Ren, Gene Colice

Allergy· June 2022

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Targeting TSLP in Asthma.
Jane R Parnes, Nestor A Molfino, Gene Colice, Ubaldo Martin, Jonathan Corren

J Asthma Allergy· June 2022

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Patient characteristics, biomarkers and exacerbation risk in severe, uncontrolled asthma.
Monica Kraft, Guy Brusselle, J Mark FitzGerald, Ian D Pavord, Matthew Keith, Gene Colice

Eur Respir J· December 2021

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Efficacy of Tezepelumab in Patients with Severe, Uncontrolled Asthma and Perennial Allergy.
Jonathan Corren, Christopher S Ambrose, Kinga Sałapa, Stephanie L Roseti, Janet M Griffiths, Gene Colice

J Allergy Clin Immunol Pract· December 2021

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Tezepelumab normalizes serum interleukin-5 and -13 levels in patients with severe, uncontrolled asthma.
Tuyet-Hang Pham, Claudia Chen, Gene Colice, Jane R Parnes, Janet M Griffiths

Ann Allergy Asthma Immunol· December 2021

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Effect of tezepelumab on airway inflammatory cells, remodelling, and hyperresponsiveness in patients with moderate-to-severe uncontrolled asthma (CASCADE): a double-blind, randomised, placebo-controlled, phase 2 trial.
Sarah Diver, Latifa Khalfaoui, Claire Emson, Sally E Wenzel, Andrew Menzies-Gow, Gene Colice

Lancet Respir Med· November 2021

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Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma.
Andrew Menzies-Gow, Jonathan Corren, Arnaud Bourdin, Geoffrey Chupp, Elliot Israel, Gene Colice

N Engl J Med· May 2021

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Functionality and Performance of an Accessorized Pre-Filled Syringe and an Autoinjector for At-Home Administration of Tezepelumab in Patients with Severe, Uncontrolled Asthma.
Sady Alpizar, Ayman Megally, Claudia Chen, Abhi Raj, John Downie, Gene Colice

J Asthma Allergy· April 2021

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Efficacy of Tezepelumab in Patients with Severe, Uncontrolled Asthma with and without Nasal Polyposis: A Analysis of the Phase 2b PATHWAY Study.
Claire Emson, Jonathan Corren, Kinga Sałapa, Åsa Hellqvist, Jane R Parnes, Gene Colice

J Asthma Allergy· February 2021

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Tezepelumab Reduces Exacerbations Across All Seasons in Patients with Severe, Uncontrolled Asthma: A Post Hoc Analysis of the PATHWAY Phase 2b Study.
Jonathan Corren, Martin Karpefors, Åsa Hellqvist, Jane R Parnes, Gene Colice

J Asthma Allergy· January 2021

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