Publications by authors named "Gillian Hunter"

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Efficacy and Safety of Tezepelumab in Adults With Severe, Uncontrolled Asthma in Asia: Results From the Phase 3 DIRECTION Study.
Xinyan Yang, Lihong Wang, Kewu Huang, Wei Tang, Eli John Berame, Gillian Hunter

J Allergy Clin Immunol Pract· November 2025

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Clinical response and on-treatment clinical remission with tezepelumab in a broad population of patients with severe, uncontrolled asthma: results over 2 years from the NAVIGATOR and DESTINATION studies.
Michael E Wechsler, Guy Brusselle, J Christian Virchow, Arnaud Bourdin, Konstantinos Kostikas, Gillian Hunter

Eur Respir J· December 2024

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Efficacy of Tezepelumab in Patients with Severe, Uncontrolled Asthma Across Multiple Clinically Relevant Subgroups in the NAVIGATOR Study.
Tara F Carr, Wendy C Moore, Monica Kraft, Guy Brusselle, Mario Castro, Gillian Hunter

Adv Ther· July 2024

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Efficacy of Biologics in Patients with Allergic Severe Asthma, Overall and by Blood Eosinophil Count: A Literature Review.
Jonathan A Bernstein, Jean-Pierre Llanos, Gillian Hunter, Neil Martin, Christopher S Ambrose

Adv Ther· November 2023

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Effect of Tezepelumab on Lung Function in Patients With Severe, Uncontrolled Asthma in the Phase 3 NAVIGATOR Study.
Andrew Menzies-Gow, Christopher S Ambrose, Gene Colice, Gillian Hunter, Bill Cook

Adv Ther· November 2023

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Effect of tezepelumab on healthcare utilization in patients with severe, uncontrolled asthma: The NAVIGATOR study.
Andrew Menzies-Gow, Arnaud Bourdin, Geoffrey Chupp, Elliot Israel, Åsa Hellqvist, Gillian Hunter

Ann Allergy Asthma Immunol· September 2023

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Efficacy and safety of tezepelumab in patients recruited in Japan who participated in the phase 3 NAVIGATOR study.
Tamotsu Ishizuka, Andrew Menzies-Gow, Hiroshi Okada, Yasushi Fukushima, Nobuya Hayashi, Gillian Hunter

Allergol Int· January 2023

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Microvasculopathy in spinal muscular atrophy is driven by a reversible autonomous endothelial cell defect.
Haiyan Zhou, Ying Hong, Mariacristina Scoto, Alison Thomson, Emma Pead, Gillian Hunter

J Clin Invest· November 2022

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Income Responses to the Affordable Care Act: Evidence from a Premium Tax Credit Notch.
Bradley T Heim, Gillian Hunter, Adam Isen, Ithai Z Lurie, Shanthi P Ramnath

J Health Econ· March 2021

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Evaluation of Antibody Properties and Clinically Relevant Immunogenicity, Anaphylaxis, and Hypersensitivity Reactions in Two Phase III Trials of Tralokinumab in Severe, Uncontrolled Asthma.
Mats Carlsson, Martin Braddock, Yuling Li, Jihong Wang, Weichen Xu, Gillian Hunter

Drug Saf· June 2019

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Restoration of SMN in Schwann cells reverses myelination defects and improves neuromuscular function in spinal muscular atrophy.
Gillian Hunter, Rachael A Powis, Ross A Jones, Ewout J N Groen, Hannah K Shorrock

Hum Mol Genet· July 2016

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Systemic restoration of UBA1 ameliorates disease in spinal muscular atrophy.
Rachael A Powis, Evangelia Karyka, Penelope Boyd, Julien Côme, Ross A Jones, Gillian Hunter

JCI Insight· July 2016

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The Impact of the ACA on Premiums: Evidence from the Self-Employed.
Bradley T Heim, Gillian Hunter, Ithai Z Lurie, Shanthi P Ramnath

J Health Polit Policy Law· October 2015

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Increased levels of UCHL1 are a compensatory response to disrupted ubiquitin homeostasis in spinal muscular atrophy and do not represent a viable therapeutic target.
Rachael A Powis, Chantal A Mutsaers, Thomas M Wishart, Gillian Hunter, Brunhilde Wirth

Neuropathol Appl Neurobiol· December 2014

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Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease.
Petroula Proitsi, Michelle K Lupton, Latha Velayudhan, Gillian Hunter, Stephen Newhouse

Neurobiol Aging· December 2014

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The influence of storage parameters on measurement of survival motor neuron (SMN) protein levels: implications for pre-clinical studies and clinical trials for spinal muscular atrophy.
Gillian Hunter, Sarah L Roche, Eilidh Somers, Heidi R Fuller, Thomas H Gillingwater

Neuromuscul Disord· November 2014

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Label-free quantitative proteomic profiling identifies disruption of ubiquitin homeostasis as a key driver of Schwann cell defects in spinal muscular atrophy.
Arwin Aghamaleky Sarvestany, Gillian Hunter, Amy Tavendale, Douglas J Lamont, Maica Llavero Hurtado

J Proteome Res· November 2014

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Label-free proteomics identifies Calreticulin and GRP75/Mortalin as peripherally accessible protein biomarkers for spinal muscular atrophy.
Chantal A Mutsaers, Douglas J Lamont, Gillian Hunter, Thomas M Wishart, Thomas H Gillingwater

Genome Med· May 2014

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SMN-dependent intrinsic defects in Schwann cells in mouse models of spinal muscular atrophy.
Gillian Hunter, Arwin Aghamaleky Sarvestany, Sarah L Roche, Rebecca C Symes, Thomas H Gillingwater

Hum Mol Genet· May 2014

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Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy.
Thomas M Wishart, Chantal A Mutsaers, Markus Riessland, Michell M Reimer, Gillian Hunter

J Clin Invest· April 2014

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