Publications by authors named "Gennaro Prota"

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Mitochondria regulate MR1 protein expression and produce self-metabolites that activate MR1-restricted T cells.
Gennaro Prota, Giuliano Berloffa, Wael Awad, Alessandro Vacchini, Andrew Chancellor

Proc Natl Acad Sci U S A· May 2025

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Remodelling of the immune landscape by IFNγ counteracts IFNγ-dependent tumour escape in mouse tumour models.
Vivian W C Lau, Gracie J Mead, Zofia Varyova, Julie M Mazet, Anagha Krishnan, Gennaro Prota

Nat Commun· January 2025

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MR1 Gene and Protein Expression Are Enhanced by Inhibition of the Extracellular Signal-Regulated Kinase ERK.
Daniel Constantin, Vladimir Nosi, Natalie Kehrer, Alessandro Vacchini, Andrew Chancellor, Gennaro Prota

Cancer Immunol Res· October 2024

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Nucleobase adducts bind MR1 and stimulate MR1-restricted T cells.
Alessandro Vacchini, Andrew Chancellor, Qinmei Yang, Rodrigo Colombo, Julian Spagnuolo, Gennaro Prota

Sci Immunol· May 2024

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Recombinant single-cycle influenza virus with exchangeable pseudotypes allows repeated immunization to augment anti-tumour immunity with immune checkpoint inhibitors.
Matheswaran Kandasamy, Uzi Gileadi, Pramila Rijal, Tiong Kit Tan, Lian N Lee, Gennaro Prota

Elife· January 2023

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Mitochondrial Proteins as Source of Cancer Neoantigens.
Gennaro Prota, Ana Victoria Lechuga-Vieco, Gennaro De Libero

Int J Mol Sci· February 2022

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Generation and characterization of HLA-A2 transgenic mice expressing the human TCR 1G4 specific for the HLA-A2 restricted NY-ESO-1 tumor-specific peptide.
Eugene Shenderov, Matheswaran Kandasamy, Uzi Gileadi, Jili Chen, Dawn Shepherd, Gennaro Prota

J Immunother Cancer· June 2021

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NOD2 and TLR2 Signal via TBK1 and PI31 to Direct Cross-Presentation and CD8 T Cell Responses.
Daniele Corridoni, Seiji Shiraishi, Thomas Chapman, Tessa Steevels, Daniele Muraro, Gennaro Prota

Front Immunol· September 2020

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Cell identity and nucleo-mitochondrial genetic context modulate OXPHOS performance and determine somatic heteroplasmy dynamics.
Ana Victoria Lechuga-Vieco, Ana Latorre-Pellicer, Iain G Johnston, Gennaro Prota, Uzi Gileadi

Sci Adv· July 2020

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Enhanced Immunogenicity of Mitochondrial-Localized Proteins in Cancer Cells.
Gennaro Prota, Uzi Gileadi, Margarida Rei, Ana Victoria Lechuga-Vieco, Ji-Li Chen

Cancer Immunol Res· May 2020

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Sterile activation of invariant natural killer T cells by ER-stressed antigen-presenting cells.
Melissa Bedard, Dilip Shrestha, David A Priestman, Yuting Wang, Falk Schneider, Gennaro Prota

Proc Natl Acad Sci U S A· November 2019

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Behaviour and neuropathology in mice injected with human contactin-associated protein 2 antibodies.
Maria Pia Giannoccaro, David A Menassa, Leslie Jacobson, Ester Coutinho, Gennaro Prota

Brain· July 2019

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Dendritic cells enter lymph vessels by hyaluronan-mediated docking to the endothelial receptor LYVE-1.
Louise A Johnson, Suneale Banerji, William Lawrance, Uzi Gileadi, Gennaro Prota

Nat Immunol· July 2017

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A Stochastic Model for CD4+ T Cell Proliferation and Dissemination Network in Primary Immune Response.
Alessandro Boianelli, Elena Pettini, Gennaro Prota, Donata Medaglini, Antonio Vicino

PLoS One· May 2016

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Peptide-specific T helper cells identified by MHC class II tetramers differentiate into several subtypes upon immunization with CAF01 adjuvanted H56 tuberculosis vaccine formulation.
Gennaro Prota, Dennis Christensen, Peter Andersen, Donata Medaglini, Annalisa Ciabattini

Vaccine· November 2015

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Characterization of the Antigen-Specific CD4(+) T Cell Response Induced by Prime-Boost Strategies with CAF01 and CpG Adjuvants Administered by the Intranasal and Subcutaneous Routes.
Annalisa Ciabattini, Gennaro Prota, Dennis Christensen, Peter Andersen, Gianni Pozzi

Front Immunol· September 2015

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Vaginal immunization to elicit primary T-cell activation and dissemination.
Elena Pettini, Gennaro Prota, Annalisa Ciabattini, Alessandro Boianelli, Fabio Fiorino

PLoS One· September 2014

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Distribution of primed T cells and antigen-loaded antigen presenting cells following intranasal immunization in mice.
Annalisa Ciabattini, Elena Pettini, Fabio Fiorino, Gennaro Prota, Gianni Pozzi

PLoS One· April 2011

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