Publications by authors named "Geor Bakker"

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Social Dysfunction and Neural Processing of Emotional Valence Across Depressive and Anxiety Disorders.
Simon Braak, Geor Bakker, Tanja Su, Channah Osinga, Laura Nawijn

Depress Anxiety· April 2025

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Source-based morphometry reveals structural brain pattern abnormalities in 22q11.2 deletion syndrome.
Ruiyang Ge, Christopher R K Ching, Anne S Bassett, Leila Kushan, Kevin M Antshel, Geor Bakker

Hum Brain Mapp· January 2024

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Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium.
Dick Schijven, Merel C Postema, Masaki Fukunaga, Junya Matsumoto, Kenichiro Miura, Geor Bakker

Proc Natl Acad Sci U S A· April 2023

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A growing understanding of the role of muscarinic receptors in the molecular pathology and treatment of schizophrenia.
Brian Dean, Geor Bakker, Hiroki R Ueda, Andrew B Tobin, Alastair Brown

Front Cell Neurosci· February 2023

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Targeting the Type 5 Metabotropic Glutamate Receptor: A Potential Therapeutic Strategy for Neurodegenerative Diseases?
Rebecca F Budgett, Geor Bakker, Eugenia Sergeev, Kirstie A Bennett, Sophie J Bradley

Front Pharmacol· May 2022

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A phase 1b/2a multicenter study of the safety and preliminary pharmacodynamic effects of selective muscarinic M receptor agonist HTL0018318 in patients with mild-to-moderate Alzheimer's disease.
Pradeep J Nathan, S Babli Millais, Alex Godwood, Odile Dewit, David M Cross, Geor Bakker

Alzheimers Dement (N Y)· February 2022

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Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs.
Ida E Sønderby, Christopher R K Ching, Sophia I Thomopoulos, Dennis van der Meer, Daqiang Sun, Geor Bakker

Hum Brain Mapp· January 2022

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Spatial Covariance of Cholinergic Muscarinic M /M Receptors in Parkinson's Disease.
Sean J Colloby, Pradeep J Nathan, Geor Bakker, Rachael A Lawson, Alison J Yarnall

Mov Disord· August 2021

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Lessons learned from using fMRI in the early clinical development of a mu-opioid receptor antagonist for disorders of compulsive consumption.
Pradeep J Nathan, Geor Bakker

Psychopharmacology (Berl)· May 2021

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Understanding Exposure-Receptor Occupancy Relationships for Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators across a Range of Preclinical and Clinical Studies.
Kirstie A Bennett, Eugenia Sergeev, Cliona P MacSweeney, Geor Bakker, Anne E Cooper

J Pharmacol Exp Ther· April 2021

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The muscarinic M receptor modulates associative learning and memory in psychotic disorders.
Geor Bakker, Claudia Vingerhoets, Oswald J N Bloemen, Barbara J Sahakian, Jan Booij

Neuroimage Clin· March 2021

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Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders.

JAMA Psychiatry· January 2021

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Altered white matter microstructure in 22q11.2 deletion syndrome: a multisite diffusion tensor imaging study.
Julio E Villalón-Reina, Kenia Martínez, Xiaoping Qu, Christopher R K Ching, Talia M Nir, Geor Bakker

Mol Psychiatry· November 2020

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Increased power by harmonizing structural MRI site differences with the ComBat batch adjustment method in ENIGMA.
Joaquim Radua, Eduard Vieta, Russell Shinohara, Peter Kochunov, Yann Quidé, Geor Bakker

Neuroimage· September 2020

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Large-scale mapping of cortical alterations in 22q11.2 deletion syndrome: Convergence with idiopathic psychosis and effects of deletion size.
Daqiang Sun, Christopher R K Ching, Amy Lin, Jennifer K Forsyth, Leila Kushan, Geor Bakker

Mol Psychiatry· August 2020

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Mapping Subcortical Brain Alterations in 22q11.2 Deletion Syndrome: Effects of Deletion Size and Convergence With Idiopathic Neuropsychiatric Illness.
Christopher R K Ching, Boris A Gutman, Daqiang Sun, Julio Villalon Reina, Anjanibhargavi Ragothaman, Geor Bakker

Am J Psychiatry· July 2020

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Cholinergic muscarinic M/M receptor networks in dementia with Lewy bodies.
Sean J Colloby, Pradeep J Nathan, Ian G McKeith, Geor Bakker, John T O'Brien

Brain Commun· July 2020

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Cholinergic muscarinic M and M receptors as therapeutic targets for cognitive, behavioural, and psychological symptoms in psychiatric and neurological disorders.
Daniel Erskine, John-Paul Taylor, Geor Bakker, Alastair J H Brown, Tim Tasker

Drug Discov Today· December 2019

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Influence of muscarinic M receptor antagonism on brain choline levels and functional connectivity in medication-free subjects with psychosis: A placebo controlled, cross-over study.
Claudia Vingerhoets, Geor Bakker, Anouk Schrantee, Marieke van der Pluijm, Oswald J N Bloemen

Psychiatry Res Neuroimaging· August 2019

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Relationship between muscarinic M receptor binding and cognition in medication-free subjects with psychosis.
Geor Bakker, Claudia Vingerhoets, Daphne Boucherie, Matthan Caan, Oswald Bloemen

Neuroimage Clin· January 2019

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Dopamine in high-risk populations: A comparison of subjects with 22q11.2 deletion syndrome and subjects at ultra high-risk for psychosis.
Claudia Vingerhoets, Oswald J N Bloemen, Erik Boot, Geor Bakker, Mariken B de Koning

Psychiatry Res Neuroimaging· February 2018

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The effect of the muscarinic M receptor antagonist biperiden on cognition in medication free subjects with psychosis.
Claudia Vingerhoets, Geor Bakker, Jelske van Dijk, Oswald J N Bloemen, Ya Wang

Eur Neuropsychopharmacol· September 2017

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Cortical Morphology Differences in Subjects at Increased Vulnerability for Developing a Psychotic Disorder: A Comparison between Subjects with Ultra-High Risk and 22q11.2 Deletion Syndrome.
Geor Bakker, Matthan W A Caan, Wilhelmina A M Vingerhoets, Fabiana da Silva-Alves, Mariken de Koning

PLoS One· July 2017

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123I-iododexetimide preferentially binds to the muscarinic receptor subtype M1 in vivo.
Geor Bakker, Wilhelmina A Vingerhoets, Jan-Peter van Wieringen, Kora de Bruin, Jos Eersels

J Nucl Med· February 2015

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Pharmacological Interventions for the MATRICS Cognitive Domains in Schizophrenia: What's the Evidence?
Wilhelmina A M Vingerhoets, Oswald J N Bloemen, Geor Bakker, Therese A M J van Amelsvoort

Front Psychiatry· December 2013

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