Publications by authors named "Andrew B Tobin"

Claim this Profile
D
Dogma-defying signalling through G proteins could lead to better pain relief.
Andrew B Tobin

Nature· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Lysine targeting covalent inhibitors of malarial kinase CLK3.
Skye B Brettell, Gillian Cann, Abbey Begen, Saumya Sharma, Amit Mahindra, Andrew B Tobin

RSC Med Chem· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Physiological Significance of Endothelial M3 Muscarinic Receptors During Exercise.
Gareth L Ackland, Patrick S Hosford, Ana Gutierrez Del Arroyo, Alla Korsak, Asif Machhada, Andrew B Tobin

Circ Res· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Optical, contact-free assessment of brain tissue stiffness and neurodegeneration.
Philip Binner, Ilya Starshynov, Gonzalo Tejeda, Aisling McFall, Colin Molloy, Andrew B Tobin

Biomed Opt Express· February 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Biased constitutive signaling of the G protein-coupled receptor GPR35 suppresses gut barrier permeability.
Tezz Quon, Li-Chiung Lin, Amlan Ganguly, Brian D Hudson, Andrew B Tobin

J Biol Chem· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting CLK3 with Covalent Inhibitors: A Novel Strategy for Malaria Treatment.
Skye B Brettell, Omar Janha, Abbey Begen, Gillian Cann, Saumya Sharma, Andrew B Tobin

J Med Chem· November 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A golden age of muscarinic acetylcholine receptor modulation in neurological diseases.
Andrew B Tobin

Nat Rev Drug Discov· October 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
O
Opportunities and challenges for the development of M muscarinic receptor positive allosteric modulators in the treatment for neurocognitive deficits.
Huong T M Nguyen, Emma T van der Westhuizen, Christopher J Langmead, Andrew B Tobin, Patrick M Sexton

Br J Pharmacol· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration under stress conditions.
Irene Fasciani, Francesco Petragnano, Ziming Wang, Ruairidh Edwards, Narasimha Telugu, Andrew B Tobin

PLoS Biol· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Phosphorylation bar-coding of free fatty acid receptor 2 is generated in a tissue-specific manner.
Natasja Barki, Laura Jenkins, Sara Marsango, Domonkos Dedeo, Daniele Bolognini, Andrew B Tobin

Elife· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design, synthesis and evaluation of novel 2-phenyl-3-(1H-pyrazol-4-yl)pyridine positive allosteric modulators for the M mAChR.
Manuela Jörg, Emma T van der Westhuizen, Yao Lu, K H Christopher Choy, David M Shackleford, Andrew B Tobin

Eur J Med Chem· October 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
G protein-receptor kinases 5/6 are the key regulators of G protein-coupled receptor 35-arrestin interactions.
Amlan Ganguly, Tezz Quon, Laura Jenkins, Babu Joseph, Rima Al-Awar, Andrew B Tobin

J Biol Chem· October 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
X
Xanomeline displays concomitant orthosteric and allosteric binding modes at the M mAChR.
Wessel A C Burger, Vi Pham, Ziva Vuckovic, Alexander S Powers, Jesse I Mobbs, Andrew B Tobin

Nat Commun· September 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A growing understanding of the role of muscarinic receptors in the molecular pathology and treatment of schizophrenia.
Brian Dean, Geor Bakker, Hiroki R Ueda, Andrew B Tobin, Alastair Brown

Front Cell Neurosci· February 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Parasite and host kinases as targets for antimalarials.
Han Wee Ong, Jack Adderley, Andrew B Tobin, David H Drewry, Christian Doerig

Expert Opin Ther Targets· February 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
M muscarinic receptor activation reduces the molecular pathology and slows the progression of prion-mediated neurodegenerative disease.
Louis Dwomoh, Mario Rossi, Miriam Scarpa, Elham Khajehali, Colin Molloy, Andrew B Tobin

Sci Signal· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
How Arrestins and GRKs Regulate the Function of Long Chain Fatty Acid Receptors.
Abdulrahman G Alharbi, Andrew B Tobin, Graeme Milligan

Int J Mol Sci· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The M muscarinic receptor is present in situ as a ligand-regulated mixture of monomers and oligomeric complexes.
Sara Marsango, Laura Jenkins, John D Pediani, Sophie J Bradley, Richard J Ward, Andrew B Tobin

Proc Natl Acad Sci U S A· June 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Selective phosphorylation of threonine residues defines GPR84-arrestin interactions of biased ligands.
Sara Marsango, Richard J Ward, Laura Jenkins, Adrian J Butcher, Zobaer Al Mahmud, Andrew B Tobin

J Biol Chem· May 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting the M1 muscarinic acetylcholine receptor in Alzheimer's disease.
Louis Dwomoh, Gonzalo S Tejeda, Andrew B Tobin

Neuronal Signal· April 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Agonist-induced phosphorylation of orthologues of the orphan receptor GPR35 functions as an activation sensor.
Nina Divorty, Laura Jenkins, Amlan Ganguly, Adrian J Butcher, Brian D Hudson, Andrew B Tobin

J Biol Chem· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Chemogenetics defines a short-chain fatty acid receptor gut-brain axis.
Natasja Barki, Daniele Bolognini, Ulf Börjesson, Laura Jenkins, John Riddell, Andrew B Tobin

Elife· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Biased M1 muscarinic receptor mutant mice show accelerated progression of prion neurodegenerative disease.
Miriam Scarpa, Colin Molloy, Laura Jenkins, Bethany Strellis, Rebecca F Budgett, Andrew B Tobin

Proc Natl Acad Sci U S A· December 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
G Protein-Coupled Receptor GPR35 Suppresses Lipid Accumulation in Hepatocytes.
Li-Chiung Lin, Tezz Quon, Susanna Engberg, Amanda E Mackenzie, Andrew B Tobin

ACS Pharmacol Transl Sci· December 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease.
Alastair J H Brown, Sophie J Bradley, Fiona H Marshall, Giles A Brown, Kirstie A Bennett, Andrew B Tobin

Cell· November 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis