Publications by authors named "George Ku"

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Inflammatory events in hippocampal slice cultures prime neuronal susceptibility to excitotoxic injury: a crucial role of P2X7 receptor-mediated IL-1beta release.
Liliana Bernardino, Silvia Balosso, Teresa Ravizza, Nicola Marchi, George Ku

J Neurochem· July 2008

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(S)-1-((S)-2-{[1-(4-amino-3-chloro-phenyl)-methanoyl]-amino}-3,3-dimethyl-butanoyl)-pyrrolidine-2-carboxylic acid ((2R,3S)-2-ethoxy-5-oxo-tetrahydro-furan-3-yl)-amide (VX-765), an orally available selective interleukin (IL)-converting enzyme/caspase-1 inhibitor, exhibits potent anti-inflammatory activities by inhibiting the release of IL-1beta and IL-18.
Woods Wannamaker, Robert Davies, Mark Namchuk, John Pollard, Pamella Ford, George Ku, Keisuke Kuida

J Pharmacol Exp Ther· May 2007

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Inactivation of caspase-1 in rodent brain: a novel anticonvulsive strategy.
Teresa Ravizza, Sian-Marie Lucas, Silvia Balosso, Liliana Bernardino, George Ku

Epilepsia· July 2006

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IL-18 translational inhibition restricts IFN-gamma expression in crescentic glomerulonephritis.
Gabriela E Garcia, Yiyang Xia, George Ku, Richard J Johnson, Curtis B Wilson

Kidney Int· July 2003

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