Publications by authors named "George Santis"

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Ligand- and integrin-independent mechano-sensitive EGFR activation in lung cancer cells.
Aneesa Shaikh, Aarmann Mohan, Milan Collins, George Santis, Maddy Parsons

J Cell Sci· November 2025

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A Retrospective Evaluation of PD-L1 Expression and Heterogeneity in Early-Stage Non-Small Cell Lung Cancer (REPLICA).
Eleni C Josephides, Daniel Smith, Andrea Bille, Akshay Patel, Hannah L Rush, George Santis

Clin Lung Cancer· May 2025

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Squamous Cell Carcinoma Arising in YAP1::MAML2 Fusion-Associated Metaplastic Thymoma: A Case Report.
Vivek Sekhawat, Martijn van der Linde, Tom Routledge, George Santis, Daisuke Nonaka

Int J Surg Pathol· April 2025

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Non-Small Cell Lung Cancer (NSCLC) in Young Adults, Age < 50, Is Associated with Late Stage at Presentation and a Very Poor Prognosis in Patients That Do Not Have a Targeted Therapy Option: A Real-World Study.
Daniel Johnathan Hughes, Matthaios Kapiris, Andreja Podvez Nevajda, Harriet McGrath, Chara Stavraka, George Santis

Cancers (Basel)· December 2022

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Epithelial coxsackievirus adenovirus receptor promotes house dust mite-induced lung inflammation.
Elena Ortiz-Zapater, Dustin C Bagley, Virginia Llopis Hernandez, Luke B Roberts, Thomas J A Maguire, George Santis

Nat Commun· October 2022

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CAR Co-Operates With Integrins to Promote Lung Cancer Cell Adhesion and Invasion.
Claudia Owczarek, Elena Ortiz-Zapater, Jana Kim, Efthymia Papaevangelou, George Santis

Front Oncol· February 2022

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Validation of Differentially Expressed Immune Biomarkers in Latent and Active Tuberculosis by Real-Time PCR.
Prem Perumal, Mohamed Bilal Abdullatif, Harriet N Garlant, Isobella Honeyborne, Marc Lipman, George Santis

Front Immunol· June 2021

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The utility and safety of linear endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in the paediatric population.
Haider Al-Najjar, Ronan Breen, George Santis, Omendra Narayan

Eur Respir J· April 2020

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The architecture of EGFR's basal complexes reveals autoinhibition mechanisms in dimers and oligomers.
Laura C Zanetti-Domingues, Dimitrios Korovesis, Sarah R Needham, Christopher J Tynan, Shiori Sagawa, George Santis

Nat Commun· October 2018

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KIF22 coordinates CAR and EGFR dynamics to promote cancer cell proliferation.
Rosemary Pike, Elena Ortiz-Zapater, Brooke Lumicisi, George Santis, Maddy Parsons

Sci Signal· January 2018

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MET-EGFR dimerization in lung adenocarcinoma is dependent on EGFR mtations and altered by MET kinase inhibition.
Elena Ortiz-Zapater, Richard W Lee, William Owen, Gregory Weitsman, Gilbert Fruhwirth, George Santis

PLoS One· August 2017

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CAR: A key regulator of adhesion and inflammation.
Elena Ortiz-Zapater, George Santis, Maddy Parsons

Int J Biochem Cell Biol· August 2017

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The Transcriptional Signature of Active Tuberculosis Reflects Symptom Status in Extra-Pulmonary and Pulmonary Tuberculosis.
Simon Blankley, Christine M Graham, Jacob Turner, Matthew P R Berry, Chloe I Bloom, George Santis

PLoS One· June 2017

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A rare intravascular tumour diagnosed by endobronchial ultrasound.
William T Owen, Elena Karampini, Ronan A Breen, Mufaddal Moonim, Arjun Nair, George Santis

Thorax· September 2016

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Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease.
Crispin T Hiley, John Le Quesne, George Santis, Rowena Sharpe, David Gonzalez de Castro

Lancet· September 2016

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A 380-gene meta-signature of active tuberculosis compared with healthy controls.
Simon Blankley, Christine M Graham, Joe Levin, Jacob Turner, Matthew P R Berry, George Santis

Eur Respir J· June 2016

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TNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers.
Penny E Morton, Alexander Hicks, Elena Ortiz-Zapater, Swetavalli Raghavan, Rosemary Pike, George Santis

Sci Rep· May 2016

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The LungPath study: variation in the diagnostic and staging pathway for patients with lung cancer in England.
Paul Cane, Karen Linklater, George Santis, Henrik Møller, Michael Peake

Thorax· March 2016

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Simultaneous FRAP, FLIM and FAIM for measurements of protein mobility and interaction in living cells.
James A Levitt, Penny E Morton, Gilbert O Fruhwirth, George Santis, Pei-Hua Chung

Biomed Opt Express· October 2015

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The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility.
Tai Kiuchi, Elena Ortiz-Zapater, James Monypenny, Daniel R Matthews, Lan K Nguyen, George Santis

Sci Signal· August 2014

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Diagnosis and subtyping of de novo and relapsed mediastinal lymphomas by endobronchial ultrasound needle aspiration.
Mufaddal T Moonim, Ronan Breen, Paul A Fields, George Santis

Am J Respir Crit Care Med· November 2013

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CAR regulates epithelial cell junction stability through control of E-cadherin trafficking.
Penny E Morton, Alexander Hicks, Theodoros Nastos, George Santis, Maddy Parsons

Sci Rep· October 2013

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CAR modulates E-cadherin dynamics in the presence of adenovirus type 5.
Fawziyah Hussain, Penny E Morton, Marjolein Snippe, Janis Sullivan, Charlotte Farmer, George Santis

PLoS One· February 2012

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Screening for EGFR and KRAS mutations in endobronchial ultrasound derived transbronchial needle aspirates in non-small cell lung cancer using COLD-PCR.
George Santis, Roger Angell, Guillermina Nickless, Alison Quinn, Amanda Herbert

PLoS One· February 2012

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Utility of endobronchial ultrasound-guided transbronchial needle aspiration in patients with tuberculous intrathoracic lymphadenopathy: a multicentre study.
Neal Navani, Philip L Molyneaux, Ronan A Breen, David W Connell, Annette Jepson, George Santis

Thorax· October 2011

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