Publications by authors named "Georges Baffet"

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long term differentiation and functionality of three-dimensional bioprinted primary human hepatocytes: application forengraftment.
Marie Cuvellier, Sophie Rose, Frédéric Ezan, Ulrich Jarry, Hugo de Oliveira, Georges Baffet

Biofabrication· June 2022

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DMSO-free highly differentiated HepaRG spheroids for chronic toxicity, liver functions and genotoxicity studies.
Sophie Rose, Marie Cuvellier, Frédéric Ezan, Jennifer Carteret, Arnaud Bruyère, Georges Baffet

Arch Toxicol· January 2022

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3D culture of HepaRG cells in GelMa and its application to bioprinting of a multicellular hepatic model.
Marie Cuvellier, Frédéric Ezan, Hugo Oliveira, Sophie Rose, Jean-Christophe Fricain, Georges Baffet

Biomaterials· February 2021

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Generation of proliferating human adult hepatocytes using optimized 3D culture conditions.
Sophie Rose, Frédéric Ezan, Marie Cuvellier, Arnaud Bruyère, Vincent Legagneux, Georges Baffet

Sci Rep· January 2021

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Molecular and tissue alterations of collagens in fibrosis.
Sylvie Ricard-Blum, Georges Baffet, Nathalie Théret

Matrix Biol· August 2018

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Determination of extracellular matrix collagen fibril architectures and pathological remodeling by polarization dependent second harmonic microscopy.
Denis Rouède, Emmanuel Schaub, Jean-Jacques Bellanger, Frédéric Ezan, Jean-Claude Scimeca, Georges Baffet

Sci Rep· September 2017

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[1-9-NαC]-crourorb A1 isolated from Croton urucurana latex induces G2/M cell cycle arrest and apoptosis in human hepatocarcinoma cells.
Priscila de Matos Cândido-Bacani, Frédéric Ezan, Patrícia de Oliveira Figueiredo, Maria de Fátima Cepa Matos, Fernanda Rodrigues Garcez, Georges Baffet

Toxicol Lett· May 2017

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Human T lymphocytes bioactivate heterocyclic aromatic amines by forming DNA adducts.
Medjda Bellamri, Ludovic Le Hegarat, Laurent Vernhet, Georges Baffet, Robert J Turesky

Environ Mol Mutagen· December 2016

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The Disintegrin and Metalloprotease ADAM12 Is Associated with TGF-β-Induced Epithelial to Mesenchymal Transition.
Michaël Ruff, Anthony Leyme, Fabienne Le Cann, Dominique Bonnier, Jacques Le Seyec, Georges Baffet

PLoS One· May 2016

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Increasing 3D Matrix Rigidity Strengthens Proliferation and Spheroid Development of Human Liver Cells in a Constant Growth Factor Environment.
Jérémy Bomo, Frédéric Ezan, François Tiaho, Medjda Bellamri, Sophie Langouët, Georges Baffet

J Cell Biochem· March 2016

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Linear least square (LLS) method for pixel-resolution analysis of polarization dependent SHG images of collagen fibrils.
Denis Rouède, Jean-Jacques Bellanger, Jérémy Bomo, Georges Baffet, François Tiaho

Opt Express· May 2015

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Integrative analysis of high-throughput RNAi screen data identifies the FER and CRKL tyrosine kinases as new regulators of the mitogenic ERK-dependent pathways in transformed cells.
Philippe Nizard, Frédéric Ezan, Dominique Bonnier, Nolwenn Le Meur, Sophie Langouët, Georges Baffet

BMC Genomics· December 2014

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Discoidin domain receptor 1 controls linear invadosome formation via a Cdc42-Tuba pathway.
Amélie Juin, Julie Di Martino, Birgit Leitinger, Elodie Henriet, Anne-Sophie Gary, Georges Baffet

J Cell Biol· November 2014

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MEK1/2 overactivation can promote growth arrest by mediating ERK1/2-dependent phosphorylation of p70S6K.
Jean-Philippe Guégan, Frédéric Ezan, Luc Gailhouste, Sophie Langouët, Georges Baffet

J Cell Physiol· July 2014

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MAPK signaling in cisplatin-induced death: predominant role of ERK1 over ERK2 in human hepatocellular carcinoma cells.
Jean-Philippe Guégan, Frédéric Ezan, Nathalie Théret, Sophie Langouët, Georges Baffet

Carcinogenesis· January 2013

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The MAPK MEK1/2-ERK1/2 Pathway and Its Implication in Hepatocyte Cell Cycle Control.
Jean-Philippe Guégan, Christophe Frémin, Georges Baffet

Int J Hepatol· November 2012

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Self-renewal of tumor-initiating cells: what's new about hepatocellular carcinoma?
Anna Alisi, Georges Baffet

Gastroenterology· June 2012

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The complexity of ERK1 and ERK2 MAPKs in multiple hepatocyte fate responses.
Christophe Frémin, Frédéric Ezan, Jean-Philippe Guegan, Luc Gailhouste, Maud Trotard, Georges Baffet

J Cell Physiol· January 2012

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Protease profiling of liver fibrosis reveals the ADAM metallopeptidase with thrombospondin type 1 motif, 1 as a central activator of transforming growth factor beta.
Katia Bourd-Boittin, Dominique Bonnier, Anthony Leyme, Bernard Mari, Pierre Tuffery, Georges Baffet

Hepatology· December 2011

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The knock-down of ERCC1 but not of XPF causes multinucleation.
Julie Rageul, Christophe Frëmin, Frédéric Ezan, Georges Baffet, Sophie Langouët

DNA Repair (Amst)· September 2011

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A robust collagen scoring method for human liver fibrosis by second harmonic microscopy.
Thomas Guilbert, Christophe Odin, Yann Le Grand, Luc Gailhouste, Bruno Turlin, Georges Baffet

Opt Express· December 2010

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RNAi-mediated MEK1 knock-down prevents ERK1/2 activation and abolishes human hepatocarcinoma growth in vitro and in vivo.
Luc Gailhouste, Frédéric Ezan, Anne Bessard, Christophe Frémin, Julie Rageul, Georges Baffet

Int J Cancer· March 2010

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Fibrillar collagen scoring by second harmonic microscopy: a new tool in the assessment of liver fibrosis.
Luc Gailhouste, Yann Le Grand, Christophe Odin, Dominique Guyader, Bruno Turlin, Georges Baffet

J Hepatol· March 2010

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Introducing the scanning air puff tonometer for biological studies.
Vincent Fleury, Alia Al-Kilani, Olena P Boryskina, Annemiek J M Cornelissen, Thi-Hanh Nguyen, Georges Baffet

Phys Rev E Stat Nonlin Soft Matter Phys· February 2010

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Multiple division cycles and long-term survival of hepatocytes are distinctly regulated by extracellular signal-regulated kinases ERK1 and ERK2.
Christophe Frémin, Anne Bessard, Frédéric Ezan, Luc Gailhouste, Morgane Régeard, Georges Baffet

Hepatology· March 2009

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