Publications by authors named "Georgia Chachami"

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Interaction of TFAP2A with the Ku70/80 complex is crucial for HIF-dependent activation of hypoxia-inducible genes.
Amalia Kanoura, Antonis Giakountis, Chrysa Filippopoulou, Angeliki Karagiota, George Stamatakis, Georgia Chachami

FEBS J· August 2025

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Promyelocytic Leukemia Protein (PML) Regulates Stem Cell Pluripotency Through Novel Sumoylation Targets.
Syrago Spanou, Takis Makatounakis, Chrysa Filippopoulou, Georgios Dougalis, George Stamatakis, Georgia Chachami

Int J Mol Sci· January 2025

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Hypoxia-driven deSUMOylation of EXOSC10 promotes adaptive changes in the transcriptome profile.
Chrysa Filippopoulou, Chairini C Thomé, Sofia Perdikari, Evgenia Ntini, George Simos, Georgia Chachami

Cell Mol Life Sci· January 2024

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Pyruvate dehydrogenase phosphatase 1 (PDP1) stimulates HIF activity by supporting histone acetylation under hypoxia.
Angeliki Karagiota, Amalia Kanoura, Efrosyni Paraskeva, George Simos, Georgia Chachami

FEBS J· April 2023

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Transcriptional Response to Hypoxia: The Role of HIF-1-Associated Co-Regulators.
Angelos Yfantis, Ilias Mylonis, Georgia Chachami, Marios Nikolaidis, Grigorios D Amoutzias

Cells· March 2023

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Comparative SUMO Proteome Analysis Using Stable Isotopic Labeling by Amino Acids (SILAC).
Georgia Chachami, Sina-Victoria Barysch

Methods Mol Biol· November 2022

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Lipid Metabolism in Cancer: The Role of Acylglycerolphosphate Acyltransferases (AGPATs).
Angeliki Karagiota, Georgia Chachami, Efrosyni Paraskeva

Cancers (Basel)· January 2022

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Specific Inhibition of HIF Activity: Can Peptides Lead the Way?
Ilias Mylonis, Georgia Chachami, George Simos

Cancers (Basel)· January 2021

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The Role of Sumoylation in the Response to Hypoxia: An Overview.
Chrysa Filippopoulou, George Simos, Georgia Chachami

Cells· October 2020

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Hypoxia-induced Changes in SUMO Conjugation Affect Transcriptional Regulation Under Low Oxygen.
Georgia Chachami, Nicolas Stankovic-Valentin, Angeliki Karagiota, Angeliki Basagianni, Uwe Plessmann

Mol Cell Proteomics· June 2019

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Protein phosphatase PPP3CA (calcineurin A) down-regulates hypoxia-inducible factor transcriptional activity.
Angeliki Karagiota, Ilias Mylonis, George Simos, Georgia Chachami

Arch Biochem Biophys· March 2019

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Low Serum Hepcidin in Patients with Autoimmune Liver Diseases.
Aggeliki Lyberopoulou, Georgia Chachami, Nikolaos K Gatselis, Eleni Kyratzopoulou, Asterios Saitis

PLoS One· May 2016

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An association study between hypoxia inducible factor-1alpha (HIF-1α) polymorphisms and osteonecrosis.
Georgia Chachami, Alkmini Kalousi, Loukia Papatheodorou, Aggeliki Lyberopoulou, Vasileios Nasikas

PLoS One· July 2014

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A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II.
Saskia Hutten, Georgia Chachami, Ulrike Winter, Frauke Melchior, Angus I Lamond

J Cell Sci· March 2014

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Oxygen-dependent secretion of a bioactive hepcidin-GFP chimera.
Georgia Chachami, Aggeliki Lyberopoulou, Alkmini Kalousi, Efrosyni Paraskeva, Kostas Pantopoulos

Biochem Biophys Res Commun· June 2013

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Epstein-Barr virus immortalization of human B-cells leads to stabilization of hypoxia-induced factor 1 alpha, congruent with the Warburg effect.
Suhas Darekar, Konstantinos Georgiou, Mariya Yurchenko, Surya Pavan Yenamandra, Georgia Chachami

PLoS One· January 2013

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Casein kinase 1 regulates human hypoxia-inducible factor HIF-1.
Alkmini Kalousi, Ilias Mylonis, Anastasia S Politou, Georgia Chachami, Efrosyni Paraskeva

J Cell Sci· September 2010

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Transport of hypoxia-inducible factor HIF-1alpha into the nucleus involves importins 4 and 7.
Georgia Chachami, Efrosyni Paraskeva, José-Manuel Mingot, Georgia G Braliou, Dirk Görlich

Biochem Biophys Res Commun· December 2009

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Atypical CRM1-dependent nuclear export signal mediates regulation of hypoxia-inducible factor-1alpha by MAPK.
Ilias Mylonis, Georgia Chachami, Efrosyni Paraskeva, George Simos

J Biol Chem· October 2008

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2-Oxoglutarate-dependent oxygenases control hepcidin gene expression.
Georgia G Braliou, Maria Vittoria Verga Falzacappa, Georgia Chachami, Guillem Casanovas, Martina U Muckenthaler

J Hepatol· May 2008

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MgcRacGAP interacts with HIF-1alpha and regulates its transcriptional activity.
Aggeliki Lyberopoulou, Emmanouil Venieris, Ilias Mylonis, Georgia Chachami, Ioannis Pappas

Cell Physiol Biochem· December 2007

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Exposure of differentiated airway smooth muscle cells to serum stimulates both induction of hypoxia-inducible factor-1{alpha} and airway responsiveness to ACh.
Georgia Chachami, Apostolia Hatziefthimiou, Panagiotis Liakos, Maria G Ioannou, Georgios K Koukoulis

Am J Physiol Lung Cell Mol Physiol· October 2007

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The flavonoid quercetin induces hypoxia-inducible factor-1alpha (HIF-1alpha) and inhibits cell proliferation by depleting intracellular iron.
Anastasia Triantafyllou, Panagiotis Liakos, Andreas Tsakalof, Georgia Chachami, Efrosyni Paraskeva

Free Radic Res· March 2007

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Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1alpha.
Ilias Mylonis, Georgia Chachami, Martina Samiotaki, George Panayotou, Efrosini Paraskeva

J Biol Chem· November 2006

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