Publications by authors named "Georgia D Tomaras"

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A polyvalent DNA prime with matched polyvalent protein/GLA-SE boost regimen elicited the most robust and broad IgG and IgG3 V1V2 binding antibody and CD4+ T cell responses among 13 HIV vaccine trials.
Zoe Moodie, Shuying Sue Li, Elena E Giorgi, LaTonya D Williams, One Dintwe, Georgia D Tomaras

Emerg Microbes Infect· December 2025

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IgG and Fc Receptor Genetic Variation Associates With Functional Antibody Responses in a DNA and Protein Candidate HIV Vaccine Trial.
Haleigh E Conley, Song Young Oh, Nigel Garrett, James Kublin, Cynthia L Monaco, Georgia D Tomaras

J Acquir Immune Defic Syndr· December 2025

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Hydrogel formulations for sustained-release of broadly neutralizing antibodies.
Carolyn K Jons, Catherine M Kasse, Bryan T Mayer, Ollivier Hyrien, Samya Sen, Georgia D Tomaras

J Control Release· December 2025

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Glycan-reactive antibodies isolated from human HIV-1 vaccine trial participants show broad pathogen cross-reactivity.
Parker J Jamieson, Xiaoying Shen, Alexandra A Abu-Shmais, Perry T Wasdin, Katarzyna Janowska, Georgia D Tomaras

J Virol· December 2025

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Myeloid cell recruitment and activation through systemic and mucosae-directed cytokine therapy.
Cordelia Manickam, Rhianna Jones, Nihar R Deb Adhikary, Kyle W Kroll, Karen Terry, Georgia D Tomaras

Immunol Cell Biol· November 2025

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HIV-1 envelope trimer vaccine induces sex-associated differences in antibody responses: a phase 1 clinical trial.
Emma I M M Reiss, Karlijn van der Straten, Laura T M Graus, Marloes Grobben, Kilian E Vlaming, Georgia D Tomaras

Nat Commun· November 2025

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Candidate correlates of protection in the HVTN505 HIV-1 vaccine efficacy trial identified by positive-unlabeled learning.
Shiwei Xu, Aaron Hudson, Holly E Janes, Georgia D Tomaras, Margaret E Ackerman

PLoS Comput Biol· November 2025

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Qualification of a reporter virus microneutralization assay for evaluation of influenza specific antibodies in human clinical trials.
Dimple Harit, Sheetal Sawant, Rachel L Spreng, Sarah Gurley, Allison Schechter, Georgia D Tomaras

Vaccine· October 2025

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Neutralizing and binding antibodies are a correlate of risk of COVID-19 in the CoVPN 3008 study in people with HIV.
Nonhlanhla N Mkhize, Bo Zhang, Caroline Brackett, Peter James Elyanu, Asa Tapley, Georgia D Tomaras

Nat Commun· October 2025

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Corrigendum to 'Immune correlates analysis of the Imbokodo (HVTN 705/HPX2008) efficacy trial of a mosaic HIV-1 vaccine regimen evaluated in Southern African people assigned female sex at birth: a two-phase case-control study'. EBioMedicine 2024;108: 105320.
Avi Kenny, Janine van Duijn, One Dintwe, Jack Heptinstall, Randy Burnham, Georgia D Tomaras

EBioMedicine· September 2025

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Candidate Correlates of Protection in the HVTN505 HIV-1 Vaccine Efficacy Trial Identified by Positive-Unlabeled Learning.
Shiwei Xu, Aaron Hudson, Holly E Janes, Georgia D Tomaras, Margaret E Ackerman

medRxiv· September 2025

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Transient regulatory T cell manipulation is limited by anti-antibody responses in HIV-1 envelope immunized rhesus macaques.
Shuqin Gu, Kan Luo, Tarra A Von Holle, Thaddeus C Gurley, Hilary Bouton-Verville, Georgia D Tomaras

iScience· August 2025

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Precise targeting of HIV broadly neutralizing antibody precursors in humans.
Tom G Caniels, Madhu Prabhakaran, Gabriel Ozorowski, Kellie J MacPhee, Weiwei Wu, Georgia D Tomaras

Science· July 2025

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Fixed dosing versus weight-based dosing of HIV-1 prophylactic monoclonal antibodies in adults: a post-hoc, cross-protocol pharmacokinetics modelling study.
Yunda Huang, Lily Zhang, Huub Gelderblom, Kelly E Seaton, Nicole L Yates, Georgia D Tomaras

EBioMedicine· July 2025

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Prior human endemic coronavirus exposure does not affect humoral responses to SARS-CoV-2 protein vaccines.
Guy de Bruyn, Haritha Adhikarla, Caroline K Brackett, Yichen Jia, Premkumar Lakshmanane, Georgia D Tomaras

NPJ Vaccines· July 2025

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Optimizing human B cell repertoire analyses to interpret clinical data and design sequential HIV vaccines.
Milton Maciel, Lindsey R Baden, Brian Briney, Nicole A Doria-Rose, Kasalina N Kiwanuka, Georgia D Tomaras

NPJ Vaccines· July 2025

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Vaccination with mRNA-encoded membrane-anchored HIV envelope trimers elicited tier 2 neutralizing antibodies in a phase 1 clinical trial.
K Rachael Parks, Zoe Moodie, Mary A Allen, Catherine Yen, Briana D Furch, Georgia D Tomaras

Sci Transl Med· July 2025

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Safety, pharmacokinetics, and neutralisation activity of PGDM1400LS, a V2 specific HIV-1 broadly neutralising antibody, infused intravenously or subcutaneously in people without HIV-1 in the USA (HVTN 140/HPTN 101 part A): a first-in-human, phase 1 randomised trial.
Kelly E Seaton, Carmen A Paez, Chenchen Yu, Shelly T Karuna, Theresa Gamble, Georgia D Tomaras

Lancet HIV· June 2025

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Engineering Sustained-Release Broadly Neutralizing Antibody Formulations.
Carolyn K Jons, Catherine M Kasse, Bryan T Mayer, Ollivier Hyrien, Samya Sen, Georgia D Tomaras

bioRxiv· June 2025

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Retrospective analysis of sex-disaggregated immune responses to ALVAC-HIV and bivalent subtype C gp120/MF59 HIV vaccines.
Cassie G Ackerley, Srilatha Edupuganti, Chenchen Yu, Alison C Roxby, Kelly E Seaton, Georgia D Tomaras

Front Immunol· May 2025

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A global collaboration for systematic analysis of broad-ranging antibodies against the SARS-CoV-2 spike protein.
Sharon L Schendel, Xiaoying Yu, Peter J Halfmann, Jarjapu Mahita, Brendan Ha, Georgia D Tomaras

Cell Rep· April 2025

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Distinct immune responses in people living with HIV following SARS-CoV-2 recovery.
Dieter Mielke, Shuying Sue Li, Daniel J Schuster, Xiaohong Li, Jiani Hu, Georgia D Tomaras

Commun Med (Lond)· April 2025

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Current Approaches for Assessments of Neutralizing, Binding, and Effector Functions of Antibodies on the Path to Antibody-Mediated Prevention Strategies for HIV-1.
David C Montefiori, Guido Ferrari, Dieter Mielke, LaTonya D Williams, Georgia D Tomaras

Curr HIV Res· March 2025

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Computationally Selected Multivalent HIV-1 Subtype C Vaccine Protects Against Heterologous SHIV Challenge.
Dieter Mielke, Marina Tuyishime, Natasha S Kelkar, Yunfei Wang, Robert Parks, Georgia D Tomaras

Vaccines (Basel)· February 2025

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A Pentavalent HIV-1 Subtype C Vaccine Containing Computationally Selected gp120 Strains Improves the Breadth of V1V2 Region Responses.
Xiaoying Shen, Bette Korber, Rachel L Spreng, Sheetal S Sawant, Allan deCamp, Georgia D Tomaras

Vaccines (Basel)· January 2025

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