Publications by authors named "Gerald Higgins"

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Water Avoidance-Stress Induces Differential Colon Transcriptomic Responses in BALB/c and C57BL/6 Mice Irritable Bowel Syndrome Model.
Suya Pang, Gerald A Higgins, John W Wiley, Xiaohua Hou, Rong Lin

Gastro Hep Adv· July 2024

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Epigenomics and the Brain-gut Axis: Impact of Adverse Childhood Experiences and Therapeutic Challenges.
John W Wiley, Gerald A Higgins

J Transl Gastroenterol· June 2024

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Glucocorticoid receptor-mediated chromatin circadian misalignment in stress-induced irritable bowel syndrome.
Gen Zheng, Suya Pang, Junbao Wang, Fangyu Wang, Qi Wang, Gerald A Higgins

iScience· July 2023

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Chronic psychological stress alters gene expression in rat colon epithelial cells promoting chromatin remodeling, barrier dysfunction and inflammation.
John W Wiley, Gerald A Higgins, Shuangsong Hong

PeerJ· January 2023

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The Role of Epigenomic Regulatory Pathways in the Gut-Brain Axis and Visceral Hyperalgesia.
Gerald A Higgins, Shaungsong Hong, John W Wiley

Cell Mol Neurobiol· March 2022

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Valproic acid-induced changes of 4D nuclear morphology in astrocyte cells.
Alexandr A Kalinin, Xinhai Hou, Alex S Ade, Gordon-Victor Fon, Walter Meixner, Gerald A Higgins

Mol Biol Cell· August 2021

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Early treatment with exosomes following traumatic brain injury and hemorrhagic shock in a swine model promotes transcriptional changes associated with neuroprotection.
Aaron M Williams, Gerald A Higgins, Umar F Bhatti, Ben E Biesterveld, Simone E Dekker

J Trauma Acute Care Surg· September 2020

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Early single-dose treatment with exosomes provides neuroprotection and improves blood-brain barrier integrity in swine model of traumatic brain injury and hemorrhagic shock.
Aaron M Williams, Umar F Bhatti, Jordana F Brown, Ben E Biesterveld, Ranganath G Kathawate, Gerald A Higgins

J Trauma Acute Care Surg· February 2020

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Druggable Transcriptional Networks in the Human Neurogenic Epigenome.
Gerald A Higgins, Aaron M Williams, Alex S Ade, Hasan B Alam, Brian D Athey

Pharmacol Rev· October 2019

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Publisher Correction: 3D Shape Modeling for Cell Nuclear Morphological Analysis and Classification.
Alexandr A Kalinin, Ari Allyn-Feuer, Alex Ade, Gordon-Victor Fon, Walter Meixner, Gerald A Higgins

Sci Rep· October 2018

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3D Shape Modeling for Cell Nuclear Morphological Analysis and Classification.
Alexandr A Kalinin, Ari Allyn-Feuer, Alex Ade, Gordon-Victor Fon, Walter Meixner, Gerald A Higgins

Sci Rep· September 2018

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Rapid valproic acid-induced modulation of the traumatic proteome in a porcine model of traumatic brain injury and hemorrhagic shock.
Michael Weykamp, Vahagn C Nikolian, Isabel S Dennahy, Gerald A Higgins, Patrick E Georgoff

J Surg Res· August 2018

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Genome Architecture Mediates Transcriptional Control of Human Myogenic Reprogramming.
Sijia Liu, Haiming Chen, Scott Ronquist, Laura Seaman, Nicholas Ceglia, Gerald Higgins

iScience· August 2018

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A similarity-based approach to leverage multi-cohort medical data on the diagnosis and prognosis of Alzheimer's disease.
Hongjiu Zhang, Fan Zhu, Hiroko H Dodge, Gerald A Higgins, Gilbert S Omenn

Gigascience· July 2018

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Deep learning in pharmacogenomics: from gene regulation to patient stratification.
Alexandr A Kalinin, Gerald A Higgins, Narathip Reamaroon, Sayedmohammadreza Soroushmehr, Ari Allyn-Feuer

Pharmacogenomics· May 2018

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Valproic acid induces prosurvival transcriptomic changes in swine subjected to traumatic injury and hemorrhagic shock.
Patrick E Georgoff, Vahagn C Nikolian, Gerald Higgins, Kiril Chtraklin, Hassan Eidy

J Trauma Acute Care Surg· April 2018

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The pharmacoepigenomics informatics pipeline defines a pathway of novel and known warfarin pharmacogenomics variants.
Ari Allyn-Feuer, Alex Ade, Jasmine A Luzum, Gerald A Higgins, Brian D Athey

Pharmacogenomics· April 2018

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Transcriptomic changes following valproic acid treatment promote neurogenesis and minimize secondary brain injury.
Vahagn C Nikolian, Isabel S Dennahy, Gerald A Higgins, Aaron M Williams, Michael Weykamp

J Trauma Acute Care Surg· March 2018

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Improvement of Blood-Brain Barrier Integrity in Traumatic Brain Injury and Hemorrhagic Shock Following Treatment With Valproic Acid and Fresh Frozen Plasma.
Vahagn C Nikolian, Simone E Dekker, Ted Bambakidis, Gerald A Higgins, Isabel S Dennahy

Crit Care Med· January 2018

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Network Reconstruction Reveals that Valproic Acid Activates Neurogenic Transcriptional Programs in Adult Brain Following Traumatic Injury.
Gerald A Higgins, Patrick Georgoff, Vahagn Nikolian, Ari Allyn-Feuer, Brian Pauls, Richard Higgins

Pharm Res· August 2017

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Mining the topography and dynamics of the 4D Nucleome to identify novel CNS drug pathways.
Gerald A Higgins, Ari Allyn-Feuer, Patrick Georgoff, Vahagn Nikolian, Hasan B Alam

Methods· July 2017

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Alterations in the human proteome following administration of valproic acid.
Patrick E Georgoff, Ihab Halaweish, Vahagn C Nikolian, Gerald A Higgins, Tess Bonham

J Trauma Acute Care Surg· December 2016

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The epigenome, 4D nucleome and next-generation neuropsychiatric pharmacogenomics.
Gerald A Higgins, Ari Allyn-Feuer, Samuel Handelman, Wolfgang Sadee, Brian D Athey

Pharmacogenomics· July 2016

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Epigenomic mapping and effect sizes of noncoding variants associated with psychotropic drug response.
Gerald A Higgins, Ari Allyn-Feuer, Brian D Athey

Pharmacogenomics· July 2016

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A glutamatergic network mediates lithium response in bipolar disorder as defined by epigenome pathway analysis.
Gerald A Higgins, Ari Allyn-Feuer, Edward Barbour, Brian D Athey

Pharmacogenomics· July 2016

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