Publications by authors named "Gerardo Morfini"

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Toxic effects of mutant huntingtin in axons are mediated by its proline-rich domain.
Scott T Brady, Nichole A Mesnard-Hoaglin, Sarah Mays, Mercedes Priego, Joanna Dziechciowska, Gerardo A Morfini

Brain· June 2024

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Divergent Molecular Pathways for Toxicity of Selected Mutant C9ORF72-derived Dipeptide Repeats.
Sonia Okekenwa, MingYing Tsai, Patrick Dooley, Bin Wang, Priscila Comassio, Gerardo Morfini

bioRxiv· June 2024

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Identifying potential imaging markers for diffusion property changes in a mouse model of amyotrophic lateral sclerosis: Application of the continuous time random walk model to ultrahigh b-value diffusion-weighted MR images of spinal cord tissue.
Jin Gao, Mingchen Jiang, Danilo Erricolo, Richard L Magin, Gerardo Morfini

NMR Biomed· January 2024

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Axon-Autonomous Effects of the Amyloid Precursor Protein Intracellular Domain (AICD) on Kinase Signaling and Fast Axonal Transport.
Svenja König, Nadine Schmidt, Karin Bechberger, Sarah Morris, Mercedes Priego, Gerardo Morfini

Cells· October 2023

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Genetic deletion of c-Jun amino-terminal kinase 3 (JNK3) modestly increases disease severity in a mouse model of multiple sclerosis.
Mercedes Priego, Lorena Noriega, Sergey Kalinin, Lisa M Hoffman, Douglas L Feinstein, Gerardo Morfini

J Neuroimmunol· September 2023

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Editorial: Kinase/phosphatase signaling and axonal function in health and disease.
Gerardo Morfini, Stefan Kins

Front Cell Neurosci· March 2023

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Modeling gain-of-function and loss-of-function components of SPAST-based hereditary spastic paraplegia using transgenic mice.
Emanuela Piermarini, Seyma Akarsu, Theresa Connors, Matthias Kneussel, Michael A Lane, Gerardo Morfini

Hum Mol Genet· June 2022

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Frontotemporal Lobar Dementia Mutant Tau Impairs Axonal Transport through a Protein Phosphatase 1γ-Dependent Mechanism.
Benjamin Combs, Kyle R Christensen, Collin Richards, Andrew Kneynsberg, Rebecca L Mueller, Gerardo A Morfini

J Neurosci· November 2021

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Therapeutic Strategies for Mutant -Based Hereditary Spastic Paraplegia.
Neha Mohan, Liang Qiang, Gerardo Morfini, Peter W Baas

Brain Sci· August 2021

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Engagement of Neurotropic Viruses in Fast Axonal Transport: Mechanisms, Potential Role of Host Kinases and Implications for Neuronal Dysfunction.
Alexsia Richards, Sarah H Berth, Scott Brady, Gerardo Morfini

Front Cell Neurosci· June 2021

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Tau: A Signaling Hub Protein.
Rebecca L Mueller, Benjamin Combs, Mohammed M Alhadidy, Scott T Brady, Gerardo A Morfini

Front Mol Neurosci· March 2021

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Defined Tau Phosphospecies Differentially Inhibit Fast Axonal Transport Through Activation of Two Independent Signaling Pathways.
Sarah L Morris, Ming-Ying Tsai, Sarah Aloe, Karin Bechberger, Svenja König, Gerardo Morfini

Front Mol Neurosci· January 2021

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Multicomponent diffusion analysis reveals microstructural alterations in spinal cord of a mouse model of amyotrophic lateral sclerosis ex vivo.
Jin Gao, Mingchen Jiang, Richard L Magin, Rodolfo G Gatto, Gerardo Morfini

PLoS One· July 2020

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Tau and Axonal Transport Misregulation in Tauopathies.
Benjamin Combs, Rebecca L Mueller, Gerardo Morfini, Scott T Brady, Nicholas M Kanaan

Adv Exp Med Biol· April 2020

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EGF Treatment Improves Motor Behavior and Cortical GABAergic Function in the R6/2 Mouse Model of Huntington's Disease.
Felecia M Marottoli, Mercedes Priego, Eden Flores-Barrera, Rohan Pisharody, Steve Zaldua, Gerardo A Morfini

Mol Neurobiol· November 2019

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Detection of axonal degeneration in a mouse model of Huntington's disease: comparison between diffusion tensor imaging and anomalous diffusion metrics.
Rodolfo G Gatto, Allen Q Ye, Luis Colon-Perez, Thomas H Mareci, Anna Lysakowski, Gerardo Morfini

MAGMA· August 2019

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Hereditary spastic paraplegia: gain-of-function mechanisms revealed by new transgenic mouse.
Liang Qiang, Emanuela Piermarini, Hemalatha Muralidharan, Wenqian Yu, Lanfranco Leo, Gerardo Morfini

Hum Mol Genet· April 2019

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Prion protein inhibits fast axonal transport through a mechanism involving casein kinase 2.
Emiliano Zamponi, Fiamma Buratti, Gabriel Cataldi, Hector Hugo Caicedo, Yuyu Song, Gerardo A Morfini

PLoS One· January 2018

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Axonal Degeneration in Tauopathies: Disease Relevance and Underlying Mechanisms.
Andrew Kneynsberg, Benjamin Combs, Kyle Christensen, Gerardo Morfini, Nicholas M Kanaan

Front Neurosci· October 2017

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Regulation of motor proteins, axonal transport deficits and adult-onset neurodegenerative diseases.
Scott T Brady, Gerardo A Morfini

Neurobiol Dis· September 2017

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Mutant spastin proteins promote deficits in axonal transport through an isoform-specific mechanism involving casein kinase 2 activation.
Lanfranco Leo, Carina Weissmann, Matthew Burns, Minsu Kang, Yuyu Song, Gerardo Morfini

Hum Mol Genet· June 2017

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Phosphoregulation of Tau modulates inhibition of kinesin-1 motility.
Jamie L Stern, Dominique V Lessard, Gregory J Hoeprich, Gerardo A Morfini, Christopher L Berger

Mol Biol Cell· April 2017

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ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation.
Reddy Ranjith K Sama, Claudia Fallini, Rodolfo Gatto, Jeanne E McKeon, Yuyu Song, Gerardo Morfini

Sci Rep· March 2017

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HIV Glycoprotein Gp120 Impairs Fast Axonal Transport by Activating Tak1 Signaling Pathways.
Sarah H Berth, Nichole Mesnard-Hoaglin, Bin Wang, Hajwa Kim, Yuyu Song, Gerardo Morfini

ASN Neuro· December 2016

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Conventional kinesin: Biochemical heterogeneity and functional implications in health and disease.
Gerardo Morfini, Nadine Schmidt, Carina Weissmann, Gustavo Pigino, Stefan Kins

Brain Res Bull· September 2016

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