Publications by authors named "Gerberick Frank"

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Quantitative next generation risk assessment for skin sensitization - application of regression models based on in vitro data to estimate point of departure.
Isabelle Lee, Mihwa Na, Maura Lavelle, Isabella Schember, Marissa A Guttenberg, G Frank Gerberick

Regul Toxicol Pharmacol· January 2026

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Applicability Domain of Peroxidase Peptide Reactivity Assay (PPRA): Chemical Structure Analysis and Grouping of Peptide Depletion Patterns.
Gang Yan, Petra S Kern, Kim Ellingson, Mengying Zhang, G Frank Gerberick

Chem Res Toxicol· October 2025

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Identification and semi-quantification of protein allergens in complex mixtures using proteomic and AllerCatPro 2.0 bioinformatic analyses: a proof-of-concept investigation.
Nora L Krutz, Ian Kimber, Jason Winget, Minh N Nguyen, Vachiranee Limviphuvadh, G Frank Gerberick

J Immunotoxicol· December 2024

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Predicting points of departure and potency categories for fragrance ingredients by integrating OECD in vitro models.
Isabelle Lee, Mihwa Na, Maura Lavelle, Isabella Schember, Cindy Ryan, G Frank Gerberick

Food Chem Toxicol· November 2024

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Deriving a point of departure for assessing the skin sensitization risk of wearable device constituents with in vitro methods.
Nakul Ruparel, Argel Islas-Robles, Allison Hilberer, Kayla Cantrell, Megan Madrid, G Frank Gerberick

Food Chem Toxicol· July 2024

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Application of AllerCatPro 2.0 for protein safety assessments of consumer products.
Nora L Krutz, Ian Kimber, Jason Winget, Minh N Nguyen, Vachiranee Limviphuvadh, G Frank Gerberick

Front Allergy· July 2023

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Updating the Dermal Sensitisation Thresholds using an expanded dataset and an in silico expert system.
Martyn L Chilton, Anne Marie Api, Robert S Foster, G Frank Gerberick, Maura Lavelle

Regul Toxicol Pharmacol· August 2022

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AllerCatPro 2.0: a web server for predicting protein allergenicity potential.
Minh N Nguyen, Nora L Krutz, Vachiranee Limviphuvadh, Andreas L Lopata, G Frank Gerberick

Nucleic Acids Res· July 2022

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Benchmarking performance of SENS-IS assay against weight of evidence skin sensitization potency categories.
Mihwa Na, Devin O'Brien, G Frank Gerberick, Petra S Kern, Maura Lavelle

Regul Toxicol Pharmacol· April 2022

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Weight of Evidence Approach for Skin Sensitization Potency Categorization of Fragrance Ingredients.
Mihwa Na, Devin O'Brien, Maura Lavelle, Isabelle Lee, G Frank Gerberick

Dermatitis· March 2022

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The microbial gbu gene cluster links cardiovascular disease risk associated with red meat consumption to microbiota L-carnitine catabolism.
Jennifer A Buffa, Kymberleigh A Romano, Matthew F Copeland, David B Cody, Weifei Zhu, G Frank Gerberick

Nat Microbiol· January 2022

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Implementation of a dermal sensitization threshold (DST) concept for risk assessment: structure-based DST and data-based DST.
Taku Nishijo, Anne Marie Api, G Frank Gerberick, Masaaki Miyazawa, Mihwa Na

Crit Rev Toxicol· January 2022

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Identifying a reference list of respiratory sensitizers for the evaluation of novel approaches to study respiratory sensitization.
Nikaeta Sadekar, Fanny Boisleve, Wolfgang Dekant, Allison D Fryer, G Frank Gerberick

Crit Rev Toxicol· November 2021

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Critical Evaluation of Low-Molecular Weight Respiratory Sensitizers and Their Protein Reactivity Potential Toward Lysine Residues.
Nora L Krutz, Ian Kimber, Cindy A Ryan, Petra S Kern, G Frank Gerberick

Toxicol Sci· August 2021

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Application of the dermal sensitization threshold concept to chemicals classified as high potency category for skin sensitization assessment of ingredients for consumer products.
Taku Nishijo, Anne Marie Api, G Frank Gerberick, Masaaki Miyazawa, David W Roberts

Regul Toxicol Pharmacol· November 2020

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Refinement of the Peroxidase Peptide Reactivity Assay and Prediction Model for Assessing Skin Sensitization Potential.
Cindy A Ryan, John A Troutman, Petra S Kern, Mike Quijano, Roy L M Dobson, G Frank Gerberick

Toxicol Sci· November 2020

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Determination of the relative allergenic potency of proteins: hurdles and opportunities.
Nora L Krutz, Ian Kimber, Sebastian Maurer-Stroh, G Frank Gerberick

Crit Rev Toxicol· July 2020

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AllerCatPro-prediction of protein allergenicity potential from the protein sequence.
Sebastian Maurer-Stroh, Nora L Krutz, Petra S Kern, Vithiagaran Gunalan, Minh N Nguyen, Frank Eisenhaber, G Frank Gerberick

Bioinformatics· September 2019

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A review of substances found positive in 1 of 3 in vitro tests for skin sensitization.
Susanne N Kolle, Andreas Natsch, G Frank Gerberick, Robert Landsiedel

Regul Toxicol Pharmacol· August 2019

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Proteomic and Bioinformatic Analyses for the Identification of Proteins With Low Allergenic Potential for Hazard Assessment.
Nora L Krutz, Jason Winget, Cindy A Ryan, Rohan Wimalasena, Sebastian Maurer-Stroh, G Frank Gerberick

Toxicol Sci· July 2019

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Quantitative risk assessment for skin sensitization: Success or failure?
Ian Kimber, G Frank Gerberick, David A Basketter

Regul Toxicol Pharmacol· February 2017

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The use of peptide reactivity assays for skin sensitisation hazard identification and risk assessment.
G Frank Gerberick

Altern Lab Anim· October 2016

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Respiratory allergenic potential of plant-derived proteins: Understanding the relationship between exposure and potency for risk assessments.
Karen Blackburn, Alhaji U N'jai, Rebecca J Dearman, Ian Kimber, G Frank Gerberick

Crit Rev Toxicol· September 2016

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Intra- and inter-laboratory reproducibility and accuracy of the LuSens assay: A reporter gene-cell line to detect keratinocyte activation by skin sensitizers.
Tzutzuy Ramirez, Nadine Stein, Alexandra Aumann, Tina Remus, Amber Edwards, Frank Gerberick

Toxicol In Vitro· April 2016

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Interleukin-1β Processing Is Dependent on a Calcium-mediated Interaction with Calmodulin.
Joseph S Ainscough, G Frank Gerberick, Ian Kimber, Rebecca J Dearman

J Biol Chem· December 2015

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