Publications by authors named "Gerhard Frey"

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Preclinical development of ozuriftamab vedotin (BA3021), a novel ROR2-specific conditionally active biologic antibody-drug conjugate.
Hwai Wen Chang, Gerhard Frey, Jing Wang, Haizhen Liu, Charles Xing

MAbs· December 2025

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Preclinical development of mecbotamab vedotin (BA3011), a novel, AXL-specific conditional active biologic antibody-drug conjugate.
Hwai Wen Chang, Jing Wang, Haizhen Liu, Charles Xing, Jian Chen, Gerhard Frey

Antib Ther· April 2025

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A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy.
Gerhard Frey, Ana Paula G Cugnetti, Haizhen Liu, Charles Xing, Christina Wheeler

MAbs· March 2024

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Generating tumor-selective conditionally active biologic anti-CTLA4 antibodies via protein-associated chemical switches.
Hwai Wen Chang, Gerhard Frey, Haizhen Liu, Charles Xing, Lawrence Steinman

Proc Natl Acad Sci U S A· March 2021

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Biocatalytic conversion of avermectin to 4''-oxo-avermectin: improvement of cytochrome p450 monooxygenase specificity by directed evolution.
Axel Trefzer, Volker Jungmann, István Molnár, Ajit Botejue, Dagmar Buckel, Gerhard Frey

Appl Environ Microbiol· July 2007

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Discovery of pectin-degrading enzymes and directed evolution of a novel pectate lyase for processing cotton fabric.
Arne I Solbak, Toby H Richardson, Ryan T McCann, Katie A Kline, Flash Bartnek, Gerhard J Frey, Geoffrey P Hazlewood

J Biol Chem· March 2005

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Regulation of the endogenous VEGF-A gene by exogenous designed regulatory proteins.
Kiyoshi Tachikawa, Oliver Schröder, Gerhard Frey, Steven P Briggs, Takashi Sera

Proc Natl Acad Sci U S A· October 2004

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An evolutionary route to xylanase process fitness.
Nisha Palackal, Yali Brennan, Walter N Callen, Paul Dupree, Gerhard Frey, Geoffrey P Hazlewood

Protein Sci· February 2004

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A novel, high performance enzyme for starch liquefaction. Discovery and optimization of a low pH, thermostable alpha-amylase.
Toby H Richardson, Xuqiu Tan, Gerhard Frey, Walter Callen, Mark Cabell

J Biol Chem· July 2002

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