Publications by authors named "Charles Xing"

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Preclinical development of ozuriftamab vedotin (BA3021), a novel ROR2-specific conditionally active biologic antibody-drug conjugate.
Hwai Wen Chang, Gerhard Frey, Jing Wang, Haizhen Liu, Charles Xing

MAbs· December 2025

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Preclinical development of mecbotamab vedotin (BA3011), a novel, AXL-specific conditional active biologic antibody-drug conjugate.
Hwai Wen Chang, Jing Wang, Haizhen Liu, Charles Xing, Jian Chen

Antib Ther· April 2025

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A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy.
Gerhard Frey, Ana Paula G Cugnetti, Haizhen Liu, Charles Xing, Christina Wheeler

MAbs· March 2024

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Topical Potassium Channel Blockage Improves Pharyngeal Collapsibility: A Translational, Placebo-Controlled Trial.
Amal M Osman, Sutapa Mukherjee, Thomas J Altree, Martina Delbeck, Doris Gehring, Charles Xing

Chest· April 2023

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BAY 2253651 for the treatment of obstructive sleep apnoea: a multicentre, double-blind, randomised controlled trial (SANDMAN).
Thomas Gaisl, Chris D Turnbull, Gerrit Weimann, Sigrun Unger, Rudolf Finger, Charles Xing

Eur Respir J· November 2021

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Generating tumor-selective conditionally active biologic anti-CTLA4 antibodies via protein-associated chemical switches.
Hwai Wen Chang, Gerhard Frey, Haizhen Liu, Charles Xing, Lawrence Steinman

Proc Natl Acad Sci U S A· March 2021

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Kinetics of 5-HT2B receptor signaling: profound agonist-dependent effects on signaling onset and duration.
David J Unett, Joel Gatlin, Todd L Anthony, Daniel J Buzard, Steve Chang, Charles Xing

J Pharmacol Exp Ther· December 2013

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Fused tricyclic indoles as S1P₁ agonists with robust efficacy in animal models of autoimmune disease.
Daniel J Buzard, Sangdon Han, Luis Lopez, Andrew Kawasaki, Jeanne Moody, Charles Xing

Bioorg Med Chem Lett· July 2012

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Discovery and characterization of potent and selective 4-oxo-4-(5-(5-phenyl-1,2,4-oxadiazol-3-yl)indolin-1-yl)butanoic acids as S1P₁ agonists.
Daniel Buzard, Sangdon Han, Lars Thoresen, Jeanne Moody, Luis Lopez, Charles Xing

Bioorg Med Chem Lett· October 2011

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Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control.
Graeme Semple, Albert Ren, Beatriz Fioravanti, Guillherme Pereira, Imelda Calderon, Charles Xing

Bioorg Med Chem Lett· May 2011

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N-oleoyldopamine enhances glucose homeostasis through the activation of GPR119.
Zhi-Liang Chu, Chris Carroll, Ruoping Chen, Jean Alfonso, Veronica Gutierrez, Charles Xing

Mol Endocrinol· January 2010

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Discovery of the first potent and orally efficacious agonist of the orphan G-protein coupled receptor 119.
Graeme Semple, Beatriz Fioravanti, Guillherme Pereira, Imelda Calderon, Jane Uy, Charles Xing

J Med Chem· September 2008

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