Publications by authors named "Gilbert Bernier"

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Epigenomic alterations and neural development anomalies in induced pluripotent stem cells from sporadic Alzheimer's disease.
Alisar Katbe, Roy Hanna, Anthony Flamier, Dounya Serhani, Rimi Hamam, Gilbert Bernier

Development· November 2025

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Pharmaceutical inhibition of the Chk2 kinase mitigates cone photoreceptor degeneration in an iPSC model of Bardet-Biedl syndrome.
Andrea Barabino, Alisar Katbe, Roy Hanna, Benjamin S Freedman, Gilbert Bernier

iScience· April 2025

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Molecular characterization and sub-retinal transplantation of hypoimmunogenic human retinal sheets in a minipig model of severe photoreceptor degeneration.
Andrea Barabino, Katia Mellal, Rimi Hamam, Anna Polosa, May Griffith, Gilbert Bernier

Development· December 2024

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Alzheimer's disease: a tale of two diseases?
Eleonora Nardini, Ryan Hogan, Anthony Flamier, Gilbert Bernier

Neural Regen Res· October 2021

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COCO/DAND5 inhibits developmental and pathological ocular angiogenesis.
Natalija Popovic, Erika Hooker, Andrea Barabino, Anthony Flamier, Frédéric Provost, Gilbert Bernier

EMBO Mol Med· March 2021

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G-quadruplexes originating from evolutionary conserved L1 elements interfere with neuronal gene expression in Alzheimer's disease.
Roy Hanna, Anthony Flamier, Andrea Barabino, Gilbert Bernier

Nat Commun· March 2021

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The Role of BMI1 in Late-Onset Sporadic Alzheimer's Disease.
Ryan Hogan, Anthony Flamier, Eleonora Nardini, Gilbert Bernier

Genes (Basel)· July 2020

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Deregulation of Neuro-Developmental Genes and Primary Cilium Cytoskeleton Anomalies in iPSC Retinal Sheets from Human Syndromic Ciliopathies.
Andrea Barabino, Anthony Flamier, Roy Hanna, Elise Héon, Benjamin S Freedman, Gilbert Bernier

Stem Cell Reports· March 2020

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Off-target effect of the BMI1 inhibitor PTC596 drives epithelial-mesenchymal transition in glioblastoma multiforme.
Anthony Flamier, Mohamed Abdouh, Rimi Hamam, Andrea Barabino, Niraj Patel, Gilbert Bernier

NPJ Precis Oncol· January 2020

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Heterochromatic genome instability and neurodegeneration sharing similarities with Alzheimer's disease in old Bmi1+/- mice.
Jida El Hajjar, Wassim Chatoo, Roy Hanna, Patrick Nkanza, Nicolas Tétreault, Gilbert Bernier

Sci Rep· January 2019

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Induction of rod versus cone photoreceptor-specific progenitors from retinal precursor cells.
Saeed Khalili, Brian G Ballios, Justin Belair-Hickey, Laura Donaldson, Jeff Liu, Gilbert Bernier

Stem Cell Res· December 2018

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INK4a/ARF Expression Impairs Neurogenesis in the Brain of Irradiated Mice.
Oanh Le, Lina Palacio, Gilbert Bernier, Ines Batinic-Haberle, Gilles Hickson

Stem Cell Reports· June 2018

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Modeling Late-Onset Sporadic Alzheimer's Disease through BMI1 Deficiency.
Anthony Flamier, Jida El Hajjar, James Adjaye, Karl J Fernandes, Mohamed Abdouh, Gilbert Bernier

Cell Rep· May 2018

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The type II transmembrane serine protease matriptase cleaves the amyloid precursor protein and reduces its processing to β-amyloid peptide.
Erwan Lanchec, Antoine Désilets, François Béliveau, Anthony Flamier, Shaimaa Mahmoud, Gilbert Bernier

J Biol Chem· December 2017

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Loss of Bmi1 causes anomalies in retinal development and degeneration of cone photoreceptors.
Andrea Barabino, Vicky Plamondon, Mohamed Abdouh, Wassim Chatoo, Anthony Flamier, Gilbert Bernier

Development· May 2016

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The Polycomb Repressive Complex 1 Protein BMI1 Is Required for Constitutive Heterochromatin Formation and Silencing in Mammalian Somatic Cells.
Mohamed Abdouh, Roy Hanna, Jida El Hajjar, Anthony Flamier, Gilbert Bernier

J Biol Chem· January 2016

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Differentiation of human embryonic stem cells into cone photoreceptors through simultaneous inhibition of BMP, TGFβ and Wnt signaling.
Shufeng Zhou, Anthony Flamier, Mohamed Abdouh, Nicolas Tétreault, Andrea Barabino, Gilbert Bernier

Development· October 2015

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ASPP1/2 regulate p53-dependent death of retinal ganglion cells through PUMA and Fas/CD95 activation in vivo.
Ariel M Wilson, Barbara Morquette, Mohamed Abdouh, Nicolás Unsain, Philip A Barker, Gilbert Bernier

J Neurosci· January 2013

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Bmi1 is down-regulated in the aging brain and displays antioxidant and protective activities in neurons.
Mohamed Abdouh, Wassim Chatoo, Jida El Hajjar, Jocelyn David, José Ferreira, Gilbert Bernier

PLoS One· August 2012

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p53 pro-oxidant activity in the central nervous system: implication in aging and neurodegenerative diseases.
Wassim Chatoo, Mohamed Abdouh, Gilbert Bernier

Antioxid Redox Signal· September 2011

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Brain cancer stem cells: current status on glioblastoma multiforme.
Sabrina Facchino, Mohamed Abdouh, Gilbert Bernier

Cancers (Basel)· March 2011

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Bmi1 distinguishes immature retinal progenitor/stem cells from the main progenitor cell population and is required for normal retinal development.
Wassim Chatoo, Mohamed Abdouh, Robert-Hugues Duparc, Gilbert Bernier

Stem Cells· August 2010

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BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery.
Sabrina Facchino, Mohamed Abdouh, Wassim Chatoo, Gilbert Bernier

J Neurosci· July 2010

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BMI1 sustains human glioblastoma multiforme stem cell renewal.
Mohamed Abdouh, Sabrina Facchino, Wassim Chatoo, Vijayabalan Balasingam, José Ferreira, Gilbert Bernier

J Neurosci· July 2009

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The LIM homeobox transcription factor Lhx2 is required to specify the retina field and synergistically cooperates with Pax6 for Six6 trans-activation.
Nicolas Tétreault, Marie-Pier Champagne, Gilbert Bernier

Dev Biol· March 2009

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