Publications by authors named "Gilles Labesse"

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Fragment-based drug design of a bacterial kinase inhibitor capable of increasing the antibiotic sensitivity of clinical isolates.
Julien Kowalewski, Robin Deutscher, Marion Richardoz, Mathilde Tomaszczyk, Muriel Gelin, Gilles Labesse

Commun Chem· November 2025

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APH Inhibitors that Reverse Aminoglycoside Resistance in Enterococcus casseliflavus.
Elise Kaplan, Laurent Chaloin, Jean-François Guichou, Kévin Berrou, Rahila Rahimova, Gilles Labesse

ChemMedChem· April 2025

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Cryo-EM structure and regulation of human NAD kinase.
Prakash P Praharaj, Yang Li, Charline Mary, Mona H Soflaee, Kevin Ryu, Gilles Labesse

Sci Adv· January 2025

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@TOME 3.0: Interfacing Protein Structure Modeling and Ligand Docking.
Jean-Luc Pons, Victor Reys, François Grand, Violaine Moreau, Jerôme Gracy, Gilles Labesse

J Mol Biol· September 2024

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SLiMAn 2.0: meaningful navigation through peptide-protein interaction networks.
Victor Reys, Jean-Luc Pons, Gilles Labesse

Nucleic Acids Res· July 2024

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Detection and Analysis of Short Linear Motif-Based Protein-Protein Interactions with SLiMAn2 Web Server.
Alexandre Mezghrani, Juliette Simon, Victor Reys, Gilles Labesse

Methods Mol Biol· July 2024

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Increases in cyclin A/Cdk activity and in PP2A-B55 inhibition by FAM122A are key mitosis-inducing events.
Benjamin Lacroix, Suzanne Vigneron, Jean Claude Labbé, Lionel Pintard, Corinne Lionne, Gilles Labesse

EMBO J· March 2024

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Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMP dehydrogenases.
Antoine Gedeon, Nour Ayoub, Sébastien Brûlé, Bertrand Raynal, Gouzel Karimova, Gilles Labesse

Protein Sci· August 2023

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Structure-based design, synthesis and biological evaluation of a NAD analogue targeting Pseudomonas aeruginosa NAD kinase.
Rahila Rahimova, Pauline Nogaret, Valérie Huteau, Muriel Gelin, David A Clément, Gilles Labesse

FEBS J· January 2023

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Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.
David A Clément, Muriel Gelin, Clarisse Leseigneur, Valérie Huteau, Lou Mondange, Gilles Labesse

Eur J Med Chem· January 2023

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Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation.
Charline Mary, Mona Hoseini Soflaee, Rushendhiran Kesavan, Muriel Gelin, Harrison Brown, Gilles Labesse

Mol Cell· September 2022

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Structural basis for the allosteric inhibition of UMP kinase from Gram-positive bacteria, a promising antibacterial target.
Patrick Walter, Ariel Mechaly, Julien Bous, Ahmed Haouz, Patrick England, Gilles Labesse

FEBS J· August 2022

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SLiMAn: An Integrative Web Server for Exploring Short Linear Motif-Mediated Interactions in Interactomes.
Victor Reys, Gilles Labesse

J Proteome Res· July 2022

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Structural evolution of the ancient enzyme, dissimilatory sulfite reductase.
Daniel R Colman, Gilles Labesse, Gurla V T Swapna, Johanna Stefanakis, Gaetano T Montelione

Proteins· June 2022

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A Histone Deacetylase (HDAC) Inhibitor with Pleiotropic In Vitro Anti- and Anti- Activities Controls Acute and Chronic Infection in Mice.
Delphine Jublot, Pierre Cavaillès, Salima Kamche, Denise Francisco, Diana Fontinha, Gilles Labesse

Int J Mol Sci· March 2022

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Structure-Based and Knowledge-Informed Design of B-Raf Inhibitors Devoid of Deleterious PXR Binding.
Melanie Schneider, Vanessa Delfosse, Muriel Gelin, Marina Grimaldi, Meritxell Granell, Gilles Labesse

J Med Chem· January 2022

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Exploring the conformational space of a receptor for drug design: An ERα case study.
Melanie Schneider, Jean-Luc Pons, Gilles Labesse

J Mol Graph Model· November 2021

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-Related Retinal Dystrophies in a Cohort of 50 Patients: A Reappraisal in the Light of Specific Müller Cell and Photoreceptor Isoforms.
Kévin Mairot, Vasily Smirnov, Béatrice Bocquet, Gilles Labesse, Carl Arndt

Int J Mol Sci· November 2021

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Retinitis Punctata Albescens and -Allied Phenotypes: Phenotype-Genotype Correlation and Natural History in the Aim of Gene Therapy.
Béatrice Bocquet, Hicham El Alami Trebki, Anne Françoise Roux, Gilles Labesse, Philippe Brabet

Ophthalmol Sci· September 2021

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Proteo3Dnet: a web server for the integration of structural information with interactomics data.
Guillaume Postic, Jessica Andreani, Julien Marcoux, Victor Reys, Raphaël Guerois, Gilles Labesse

Nucleic Acids Res· July 2021

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The study of the determinants controlling Arpp19 phosphatase-inhibitory activity reveals an Arpp19/PP2A-B55 feedback loop.
Jean Claude Labbé, Suzanne Vigneron, Francisca Méchali, Perle Robert, Sylvain Roque, Gilles Labesse

Nat Commun· June 2021

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The Dynamic Ion Motive Force Powering the Bacterial Flagellar Motor.
Anaïs Biquet-Bisquert, Gilles Labesse, Francesco Pedaci, Ashley L Nord

Front Microbiol· April 2021

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An oligomeric switch controls the Mrr-induced SOS response in E. coli.
Anaïs C Bourges, Oscar E Torres Montaguth, Wubishet Tadesse, Gilles Labesse, Abram Aertsen

DNA Repair (Amst)· January 2021

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[In silico profiling of protein kinases inhibitors].
Victor Reys, Gilles Labesse

Med Sci (Paris)· October 2020

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New Chemical Probe Targeting Bacterial NAD Kinase.
David A Clément, Clarisse Leseigneur, Muriel Gelin, Dylan Coelho, Valérie Huteau, Gilles Labesse

Molecules· October 2020

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