Publications by authors named "Julien Bous"

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Inactive structures of the vasopressin V2 receptor reveal distinct binding modes for Tolvaptan and Mambaquaretin toxin.
Aurélien Fouillen, Julien Bous, Pierre Couvineau, Hélène Orcel, Charline Mary

Nat Commun· April 2025

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Structural basis of frizzled 7 activation and allosteric regulation.
Julien Bous, Julia Kinsolving, Lukas Grätz, Magdalena M Scharf, Jan Hendrik Voss

Nat Commun· August 2024

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Frizzleds act as dynamic pharmacological entities.
Gunnar Schulte, Magdalena M Scharf, Julien Bous, Jan Hendrik Voss, Lukas Grätz

Trends Pharmacol Sci· May 2024

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Structural and functional insight into the interaction of Clostridioides difficile toxin B and FZD.
Julia Kinsolving, Julien Bous, Pawel Kozielewicz, Sara Košenina, Rawan Shekhani

Cell Rep· February 2024

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Structures of the arginine-vasopressin and oxytocin receptor signaling complexes.
Julien Bous, Aurélien Fouillen, Hélène Orcel, Sébastien Granier, Patrick Bron

Vitam Horm· September 2023

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Pathway selectivity in Frizzleds is achieved by conserved micro-switches defining pathway-determining, active conformations.
Lukas Grätz, Maria Kowalski-Jahn, Magdalena M Scharf, Pawel Kozielewicz, Michael Jahn, Julien Bous

Nat Commun· July 2023

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Bringing GPCR Structural Biology to Medical Applications: Insights from Both V2 Vasopressin and Mu-Opioid Receptors.
Aurélien Fouillen, Julien Bous, Sébastien Granier, Bernard Mouillac, Remy Sounier

Membranes (Basel)· June 2023

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Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex.
Jakub Gruszczyk, Loïc Grandvuillemin, Josephine Lai-Kee-Him, Matteo Paloni, Christos G Savva, Julien Bous

Nat Commun· November 2022

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Structure of the vasopressin hormone-V2 receptor-β-arrestin1 ternary complex.
Julien Bous, Aurélien Fouillen, Hélène Orcel, Stefano Trapani, Xiaojing Cong

Sci Adv· September 2022

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Structural basis for the allosteric inhibition of UMP kinase from Gram-positive bacteria, a promising antibacterial target.
Patrick Walter, Ariel Mechaly, Julien Bous, Ahmed Haouz, Patrick England

FEBS J· August 2022

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Cryo-electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex.
Julien Bous, Hélène Orcel, Nicolas Floquet, Cédric Leyrat, Joséphine Lai-Kee-Him

Sci Adv· May 2021

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