Publications by authors named "Sebastien Granier"

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Constitutive activity of an atypical chemokine receptor revealed by inverse agonistic nanobodies.
Claudia V Perez Almeria, Omolade Otun, Roman Schlimgen, Thomas D Lamme, Lotte Di Niro, Sébastien Granier

Nat Commun· December 2025

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TR-FRET between engineered nanobodies reveals the existence of endogenous CXCR4 oligomers.
Joyce Heuninck, Vladimir Bobkov, Claire M Grison, Amos Fumagalli, Mathias Lescuyer, Sébastien Granier

Commun Biol· December 2025

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Chemokine receptors - Exemplifying functional divergence in G protein-coupled receptors.
Omolade Otun, Sébastien Granier, Thierry Durroux, Cherine Bechara

Mol Pharmacol· July 2025

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Inactive structures of the vasopressin V2 receptor reveal distinct binding modes for Tolvaptan and Mambaquaretin toxin.
Aurélien Fouillen, Julien Bous, Pierre Couvineau, Hélène Orcel, Charline Mary, Sébastien Granier

Nat Commun· April 2025

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Biased activation of the vasopressin V2 receptor probed by molecular dynamics simulations, NMR and pharmacological studies.
Aurélien Fouillen, Pierre Couvineau, Gérald Gaibelet, Stéphanie Riché, Hélène Orcel, Sébastien Granier

Comput Struct Biotechnol J· December 2024

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Constitutive activity of an atypical chemokine receptor revealed by inverse agonistic nanobodies.
Claudia V Perez Almeria, Omolade Otun, Roman Schlimgen, Thomas D Lamme, Caitrin Crudden, Sébastien Granier

bioRxiv· November 2024

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Design, Synthesis, and Characterization of New δ Opioid Receptor-Selective Fluorescent Probes and Applications in Single-Molecule Microscopy of Wild-Type Receptors.
Antonios Drakopoulos, Zsombor Koszegi, Kerstin Seier, Harald Hübner, Damien Maurel, Sébastien Granier

J Med Chem· August 2024

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Conformational dynamics underlying atypical chemokine receptor 3 activation.
Omolade Otun, Christelle Aljamous, Elise Del Nero, Marta Arimont-Segura, Reggie Bosma, Sébastien Granier

Proc Natl Acad Sci U S A· July 2024

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Structures of the arginine-vasopressin and oxytocin receptor signaling complexes.
Julien Bous, Aurélien Fouillen, Hélène Orcel, Sébastien Granier, Patrick Bron

Vitam Horm· September 2023

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Structure, dynamics and transferability of the metal-dependent polyhistidine tetramerization motif TetrHis for single-chain Fv antibodies.
Robert D Healey, Louise Couillaud, François Hoh, Assia Mouhand, Aurelien Fouillen, Sébastien Granier

Commun Chem· July 2023

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Bringing GPCR Structural Biology to Medical Applications: Insights from Both V2 Vasopressin and Mu-Opioid Receptors.
Aurélien Fouillen, Julien Bous, Sébastien Granier, Bernard Mouillac, Remy Sounier

Membranes (Basel)· June 2023

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Structure of the vasopressin hormone-V2 receptor-β-arrestin1 ternary complex.
Julien Bous, Aurélien Fouillen, Hélène Orcel, Stefano Trapani, Xiaojing Cong, Sébastien Granier

Sci Adv· September 2022

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Structural insights into recognition of chemokine receptors by leukotoxins.
Paul Lambey, Omolade Otun, Xiaojing Cong, François Hoh, Luc Brunel, Sébastien Granier

Elife· March 2022

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Discovery and Mechanism of Action of Small Molecule Inhibitors of Ceramidases.
Robert D Healey, Essa M Saied, Xiaojing Cong, Gergely Karsai, Ludovic Gabellier, Sebastien Granier

Angew Chem Int Ed Engl· January 2022

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Molecular insights into the biased signaling mechanism of the μ-opioid receptor.
Xiaojing Cong, Damien Maurel, Hélène Déméné, Ieva Vasiliauskaité-Brooks, Joanna Hagelberger, Sébastien Granier

Mol Cell· October 2021

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Molecular insights into mechanisms of GPCR hijacking by .
Claire M Grison, Paul Lambey, Sylvain Jeannot, Elise Del Nero, Simon Fontanel, Sébastien Granier

Proc Natl Acad Sci U S A· October 2021

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An automated platform for structural analysis of membrane proteins through serial crystallography.
Robert D Healey, Shibom Basu, Anne-Sophie Humm, Cedric Leyrat, Xiaojing Cong, Sébastien Granier

Cell Rep Methods· October 2021

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Cryo-electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex.
Julien Bous, Hélène Orcel, Nicolas Floquet, Cédric Leyrat, Joséphine Lai-Kee-Him, Sébastien Granier

Sci Adv· May 2021

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Modular Imaging Scaffold for Single-Particle Electron Microscopy.
Nesrine Aissaoui, Josephine Lai-Kee-Him, Allan Mills, Nathalie Declerck, Zakia Morichaud, Sébastien Granier

ACS Nano· March 2021

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Author Correction: Structural insights into μ-opioid receptor activation.
Weijiao Huang, Aashish Manglik, A J Venkatakrishnan, Toon Laeremans, Evan N Feinberg, Sébastien Granier

Nature· August 2020

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Selective and Wash-Resistant Fluorescent Dihydrocodeinone Derivatives Allow Single-Molecule Imaging of μ-Opioid Receptor Dimerization.
Christian Gentzsch, Kerstin Seier, Antonios Drakopoulos, Marie-Lise Jobin, Yann Lanoiselée, Sébastien Granier

Angew Chem Int Ed Engl· April 2020

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7TM proteins are not necessarily GPCRs.
Ieva Vasiliauskaité-Brooks, Robert D Healey, Sébastien Granier

Mol Cell Endocrinol· July 2019

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GNAS: A New Nephrogenic Cause of Inappropriate Antidiuresis.
Daniel G Bichet, Sébastien Granier, Detlef Bockenhauer

J Am Soc Nephrol· May 2019

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Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy.
Ieva Vasiliauskaité-Brooks, Robert D Healey, Pascal Rochaix, Julie Saint-Paul, Rémy Sounier, Sébastien Granier

Nat Commun· December 2018

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Structure of the µ-opioid receptor-G protein complex.
Antoine Koehl, Hongli Hu, Shoji Maeda, Yan Zhang, Qianhui Qu, Sebastien Granier

Nature· June 2018

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