Publications by authors named "Graeme Sullivan"

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Endothelial IL-36 receptor activation promotes vascular stability to limit pathological microvessel permeability in the CNS.
Erin Fahey, Lucia Celkova, Valentina Frezza, Graeme P Sullivan, Kieran Byrne

Cell Rep· November 2025

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Serine-arginine protein kinase 1 (SRPK1) is under-expressed in mucinous colorectal cancer, and may mediate resistance to oxaliplatin.
William P Duggan, Mohammedreza Azimi, Lyndsey Flanagan, Graeme P Sullivan, Ian S Reynolds

Pharmacogenomics J· October 2025

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First-in-class metallo-PROTAC as an effective degrader of select Pt-binding proteins.
Paul D O'Dowd, Graeme P Sullivan, Daniel A Rodrigues, Tríona Ní Chonghaile, Darren M Griffith

Chem Commun (Camb)· October 2023

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The path to venetoclax resistance is paved with mutations, metabolism, and more.
Graeme P Sullivan, Lyndsey Flanagan, Daniel Alencar Rodrigues, Tríona Ní Chonghaile

Sci Transl Med· December 2022

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Myeloid cell-derived proteases produce a proinflammatory form of IL-37 that signals via IL-36 receptor engagement.
Graeme P Sullivan, Pavel Davidovich, Natalia Muñoz-Wolf, Ross W Ward, Yasmina E Hernandez Santana

Sci Immunol· December 2022

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IL-1α and IL-36 Family Cytokines Can Undergo Processing and Activation by Diverse Allergen-Associated Proteases.
Valentina Frezza, Zaneta Najda, Pavel Davidovich, Graeme P Sullivan, Seamus J Martin

Front Immunol· July 2022

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TRAIL Receptors Serve as Stress-Associated Molecular Patterns to Promote ER-Stress-Induced Inflammation.
Graeme P Sullivan, Hazel O'Connor, Conor M Henry, Pavel Davidovich, Danielle M Clancy

Dev Cell· March 2020

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iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.
Ioanna Oikonomidi, Emma Burbridge, Miguel Cavadas, Graeme Sullivan, Blanka Collis

Elife· June 2018

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Identification of small-molecule elastase inhibitors as antagonists of IL-36 cytokine activation.
Graeme P Sullivan, Pavel B Davidovich, Sylvia Sura-Trueba, Ekaterina Belotcerkovskaya, Conor M Henry

FEBS Open Bio· May 2018

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Suppressing IL-36-driven inflammation using peptide pseudosubstrates for neutrophil proteases.
Graeme P Sullivan, Conor M Henry, Danielle M Clancy, Tazhir Mametnabiev, Ekaterina Belotcerkovskaya

Cell Death Dis· March 2018

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Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing.
Danielle M Clancy, Graeme P Sullivan, Hannah B T Moran, Conor M Henry, Emer P Reeves

Cell Rep· March 2018

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Neutrophil extracellular traps can serve as platforms for processing and activation of IL-1 family cytokines.
Danielle M Clancy, Conor M Henry, Graeme P Sullivan, Seamus J Martin

FEBS J· June 2017

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Production of biologically active IL-36 family cytokines through insertion of N-terminal caspase cleavage motifs.
Danielle M Clancy, Conor M Henry, Pavel B Davidovich, Graeme P Sullivan, Ekaterina Belotcerkovskaya

FEBS Open Bio· April 2016

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Neutrophil-Derived Proteases Escalate Inflammation through Activation of IL-36 Family Cytokines.
Conor M Henry, Graeme P Sullivan, Danielle M Clancy, Inna S Afonina, Dagmar Kulms

Cell Rep· February 2016

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