Publications by authors named "Graeme Thomson"

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Patient and public involvement and engagement in the ASCEND PLUS trial: reflections from the design of a streamlined and decentralised clinical trial.
Muram El-Nayir, Rohan Wijesurendra, David Preiss, Marion Mafham, Leandros Tsiotos, Graeme Thomson

Trials· August 2024

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2-Aminomethylene-5-sulfonylthiazole Inhibitors of Lysyl Oxidase (LOX) and LOXL2 Show Significant Efficacy in Delaying Tumor Growth.
Deborah A Smithen, Leo M H Leung, Mairi Challinor, Rae Lawrence, HaoRan Tang, Graeme Thomson

J Med Chem· March 2020

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Small-Molecule Inhibition of UBE2T/FANCL-Mediated Ubiquitylation in the Fanconi Anemia Pathway.
Matthew J Cornwell, Graeme J Thomson, Julia Coates, Rimma Belotserkovskaya, Ian D Waddell

ACS Chem Biol· October 2019

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Discovery and Optimization of Allosteric Inhibitors of Mutant Isocitrate Dehydrogenase 1 (R132H IDH1) Displaying Activity in Human Acute Myeloid Leukemia Cells.
Stuart Jones, Jonathan Ahmet, Kelly Ayton, Matthew Ball, Mark Cockerill, Graeme Thomson

J Med Chem· December 2016

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The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity.
Rebecca Newton, Katherine A Bowler, Emily M Burns, Philip J Chapman, Emma E Fairweather, Graeme J Thomson

Eur J Med Chem· April 2016

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A fluorescence-based assay for the apurinic/apyrimidinic-site cleavage activity of human tyrosyl-DNA phosphodiesterase 1.
Graeme J Thomson, Nicola S Hamilton, Gemma V Hopkins, Ian D Waddell, Amanda J Watson

Anal Biochem· September 2013

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Toxoflavins and deazaflavins as the first reported selective small molecule inhibitors of tyrosyl-DNA phosphodiesterase II.
Ali Raoof, Paul Depledge, Niall M Hamilton, Nicola S Hamilton, James R Hitchin, Graeme J Thomson

J Med Chem· August 2013

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Generation of assays and antibodies to facilitate the study of human 5'-tyrosyl DNA phosphodiesterase.
Graeme Thomson, Amanda Watson, Keith Caldecott, Olive Denneny, Paul Depledge

Anal Biochem· May 2013

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Novel steroid inhibitors of glucose 6-phosphate dehydrogenase.
Niall M Hamilton, Martin Dawson, Emma E Fairweather, Nicola S Hamilton, James R Hitchin, Graeme J Thomson

J Med Chem· May 2012

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High throughput screens yield small molecule inhibitors of Leishmania CRK3:CYC6 cyclin-dependent kinase.
Roderick G Walker, Graeme Thomson, Kirk Malone, Matthew W Nowicki, Elaine Brown

PLoS Negl Trop Dis· April 2011

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Accuracy of electrocardiogram interpretation improves with emergency medicine training.
Rachel J Hoyle, Katherine J Walker, Graeme Thomson, Michael Bailey

Emerg Med Australas· April 2007

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