Publications by authors named "Graham D Smith"

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Optimization of Potent and Selective Ataxia Telangiectasia-Mutated Inhibitors Suitable for a Proof-of-Concept Study in Huntington's Disease Models.
Leticia Toledo-Sherman, Perla Breccia, Roger Cachope, Jennifer R Bate, Ivan Angulo-Herrera, Graham D Smith

J Med Chem· March 2019

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Brachytherapy improves biochemical failure-free survival in low- and intermediate-risk prostate cancer compared with conventionally fractionated external beam radiation therapy: a propensity score matched analysis.
Graham D Smith, Tom Pickles, Juanita Crook, Andre-Guy Martin, Eric Vigneault

Int J Radiat Oncol Biol Phys· March 2015

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Characterization of a recurrent in-frame UMOD indel mutation causing late-onset autosomal dominant end-stage renal failure.
Graham D Smith, Caroline Robinson, Andrew P Stewart, Emily L Edwards, Hannah I Karet

Clin J Am Soc Nephrol· December 2011

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Atomic force microscopy reveals the alternating subunit arrangement of the TRPP2-TRPV4 heterotetramer.
Andrew P Stewart, Graham D Smith, Richard N Sandford, J Michael Edwardson

Biophys J· August 2010

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The transient receptor potential channels TRPP2 and TRPC1 form a heterotetramer with a 2:2 stoichiometry and an alternating subunit arrangement.
Toshiro Kobori, Graham D Smith, Richard Sandford, J Michael Edwardson

J Biol Chem· December 2009

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The discovery of a selective, small molecule agonist for the MAS-related gene X1 receptor.
Berthold Wroblowski, Mark J Wigglesworth, Philip G Szekeres, Graham D Smith, Shahzad S Rahman

J Med Chem· February 2009

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Activation of recombinant human TRPV1 receptors expressed in SH-SY5Y human neuroblastoma cells increases [Ca(2+)](i), initiates neurotransmitter release and promotes delayed cell death.
Patricia M W Lam, Atticus H Hainsworth, Graham D Smith, Davina E Owen, James Davies

J Neurochem· August 2007

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Characterization of SB-705498, a potent and selective vanilloid receptor-1 (VR1/TRPV1) antagonist that inhibits the capsaicin-, acid-, and heat-mediated activation of the receptor.
Martin J Gunthorpe, Sara Luis Hannan, Darren Smart, Jeffrey C Jerman, Sandra Arpino, Graham D Smith

J Pharmacol Exp Ther· June 2007

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Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy.
Paul Facer, Maria A Casula, Graham D Smith, Christopher D Benham, Iain P Chessell

BMC Neurol· May 2007

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Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations.
Gaurav Mukerji, Yiangos Yiangou, Stacey L Corcoran, Inger S Selmer, Graham D Smith

BMC Urol· March 2006

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Arthroscopic assessment of cartilage repair: a validation study of 2 scoring systems.
Graham D Smith, Jo Taylor, Karl Fredrik Almqvist, Christoph Erggelet, Gunnar Knutsen, Tony Smith

Arthroscopy· December 2005

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Increased capsaicin receptor TRPV1 in skin nerve fibres and related vanilloid receptors TRPV3 and TRPV4 in keratinocytes in human breast pain.
Preethi Gopinath, Elaine Wan, Anita Holdcroft, Paul Facer, John B Davis, Graham D Smith

BMC Womens Health· March 2005

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Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives.
Hiroyuki Watanabe, John B Davis, Darren Smart, Jeff C Jerman, Graham D Smith

J Biol Chem· April 2002

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Cloning and functional expression of a human orthologue of rat vanilloid receptor-1.
Philip Hayes, Helen J Meadows, Martin J Gunthorpe, Mark H Harries, Malcolm D Duckworth, Graham D Smith

Pain· November 2000

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