Publications by authors named "Graham Duddy"

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Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis.
Malgorzata Gozdecka, Monika Dudek, Sean Wen, Muxin Gu, Richard J Stopforth, Graham Duddy

Nature· June 2025

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Epi-microRNA mediated metabolic reprogramming counteracts hypoxia to preserve affinity maturation.
Rinako Nakagawa, Miriam Llorian, Sunita Varsani-Brown, Probir Chakravarty, Jeannie M Camarillo, Graham Duddy

Nat Commun· December 2024

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Pathological mechanisms and candidate therapeutic approaches in the hearing loss of mice carrying human MIR96 mutations.
Morag A Lewis, Maria Lachgar-Ruiz, Francesca Di Domenico, Graham Duddy, Jing Chen

Genome Med· October 2024

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Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines.
Hillary Elrick, Kevin A Peterson, Brandon J Willis, Denise G Lanza, Elif F Acar, Graham Duddy

Sci Rep· September 2024

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Donor template delivery by recombinant adeno-associated virus for the production of knock-in mice.
Graham Duddy, Katherine Courtis, Juliette Horwood, Jessica Olsen, Helen Horsler

BMC Biol· February 2024

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Epi-microRNA mediated metabolic reprogramming ensures affinity maturation.
Rinako Nakagawa, Miriam Llorian, Sunita Varsani-Brown, Probir Chakravarty, Jeannie M Camarillo, Graham Duddy

bioRxiv· October 2023

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Tumors induce de novo steroid biosynthesis in T cells to evade immunity.
Bidesh Mahata, Jhuma Pramanik, Louise van der Weyden, Krzysztof Polanski, Gozde Kar, Graham Duddy

Nat Commun· July 2020

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Genome-wide CRISPR Screens in T Helper Cells Reveal Pervasive Crosstalk between Activation and Differentiation.
Johan Henriksson, Xi Chen, Tomás Gomes, Ubaid Ullah, Kerstin B Meyer, Graham Duddy

Cell· February 2019

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Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors.
Genta Ito, Kristina Katsemonova, Francesca Tonelli, Pawel Lis, Marco A S Baptista, Graham Duddy

Biochem J· September 2016

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Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.
Martin Steger, Francesca Tonelli, Genta Ito, Paul Davies, Matthias Trost, Graham Duddy

Elife· January 2016

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Characterisation of a K390R ITK kinase dead transgenic mouse--implications for ITK as a therapeutic target.
Angela Deakin, Graham Duddy, Steve Wilson, Steve Harrison, Judi Latcham

PLoS One· June 2015

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Targeting apoptosis signalling kinase-1 (ASK-1) does not prevent the development of neuropathy in streptozotocin-induced diabetic mice.
Victoria L Newton, Sumia Ali, Graham Duddy, Alan J Whitmarsh, Natalie J Gardiner

PLoS One· June 2015

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Evaluation of expression and function of the H+/myo-inositol transporter HMIT.
Elena Di Daniel, Man H S Mok, Emma Mead, Chiara Mutinelli, Erika Zambello, Graham Duddy

BMC Cell Biol· July 2009

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BACE1 (beta-secretase) transgenic and knockout mice: identification of neurochemical deficits and behavioral changes.
Steve M Harrison, Alex J Harper, Julie Hawkins, Graham Duddy, Evelyn Grau

Mol Cell Neurosci· November 2003

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Molecular and pharmacological characterization of genes encoding urotensin-II peptides and their cognate G-protein-coupled receptors from the mouse and monkey.
Nabil A Elshourbagy, Stephen A Douglas, Usman Shabon, Stephen Harrison, Graham Duddy

Br J Pharmacol· May 2002

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