Publications by authors named "Graham G Inglis"

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Identification of an active metabolite of PAR-1 antagonist RWJ-58259 and synthesis of analogues to enhance its metabolic stability.
Eifion Robinson, Emily Knight, Natalia Smoktunowicz, Rachel C Chambers, Graham G Inglis

Org Biomol Chem· March 2016

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Synthesis of novel and potent vorapaxar analogues.
Emily Knight, Eifion Robinson, Natalia Smoktunowicz, Rachel C Chambers, Abil E Aliev, Graham G Inglis

Org Biomol Chem· March 2016

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A practical drug discovery project at the undergraduate level.
M Jonathan Fray, Simon J F Macdonald, Ian R Baldwin, Nick Barton, Jack Brown, Graham G A Inglis

Drug Discov Today· December 2013

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Synthesis and functionalization of 3-alkylidene-1,2-diazetidines using transition metal catalysis.
Michael J Brown, Guy J Clarkson, Graham G Inglis, Michael Shipman

Org Lett· April 2011

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Nonsteroidal glucocorticoid agonists: tetrahydronaphthalenes with alternative steroidal A-ring mimetics possessing dissociated (transrepression/transactivation) efficacy selectivity.
Keith Biggadike, Mohamed Boudjelal, Margaret Clackers, Diane M Coe, Derek A Demaine, Graham G A Inglis

J Med Chem· December 2007

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Non-steroidal glucocorticoid agonists: the discovery of aryl pyrazoles as A-ring mimetics.
Margaret Clackers, Diane M Coe, Derek A Demaine, George W Hardy, Davina Humphreys, Graham G A Inglis

Bioorg Med Chem Lett· September 2007

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Carbon-carbon bond forming reactions with substrates absorbed non-covalently on a cellulose chromatography paper support.
Jonathon Hacon, Amanda Morris, Michael J Johnston, Stephen E Shanahan, Mike D Barker, Graham G A Inglis

Chem Commun (Camb)· February 2007

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Dissociated nonsteroidal glucocorticoid receptor modulators; discovery of the agonist trigger in a tetrahydronaphthalene-benzoxazine series.
Mike Barker, Margaret Clackers, Royston Copley, Derek A Demaine, Davina Humphreys, Graham G A Inglis

J Med Chem· July 2006

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Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenza.
Simon J F Macdonald, Rachel Cameron, Derek A Demaine, Rob J Fenton, Graham Foster, Graham G A Inglis

J Med Chem· April 2005

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Potent and long-acting dimeric inhibitors of influenza virus neuraminidase are effective at a once-weekly dosing regimen.
Simon J F Macdonald, Keith G Watson, Rachel Cameron, David K Chalmers, Derek A Demaine, Graham G A Inglis

Antimicrob Agents Chemother· December 2004

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Discovery of further pyrrolidine trans-lactams as inhibitors of human neutrophil elastase (HNE) with potential as development candidates and the crystal structure of HNE complexed with an inhibitor (GW475151).
Simon J F Macdonald, Michael D Dowle, Lee A Harrison, Geoffrey D E Clarke, Graham G A Inglis

J Med Chem· August 2002

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