Publications by authors named "Graham Leggatt"

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Squamous cell carcinoma is associated with reduced IL34 expression, alterations in the Langerhans cell antigen-processing-presentation machinery and poor patient survival.
Thi Viet Trinh Dang, Kevin R Gillinder, Quan Nguyen, Onkar Mulay, Tuan Vo, Graham R Leggatt

Clin Transl Immunology· November 2024

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Metabolomics at the tumor microenvironment interface: Decoding cellular conversations.
Naomi Berrell, Habib Sadeghirad, Tony Blick, Charles Bidgood, Graham R Leggatt

Med Res Rev· May 2024

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Peritumoral administration of immunomodulatory antibodies as a triple combination suppresses skin tumor growth without systemic toxicity.
Quentin G Wright, Debottam Sinha, James W Wells, Ian H Frazer, Jazmina L Gonzalez Cruz, Graham Robert Leggatt

J Immunother Cancer· January 2024

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PD-1 and beyond to Activate T Cells in Cutaneous Squamous Cell Cancers: The Case for 4-1BB and VISTA Antibodies in Combination Therapy.
Quentin Wright, Jazmina L Gonzalez Cruz, James W Wells, Graham R Leggatt

Cancers (Basel)· July 2021

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Regulatory T Cells but Not IL-10 Impair Cell-Mediated Immunity in Human Papillomavirus E7+ Hyperplastic Epithelium.
Abate Assefa Bashaw, Chenhao Zhou, Meihua Yu, Lynn Tolley, Graham R Leggatt

J Invest Dermatol· May 2021

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Evolution of Cancer Vaccines-Challenges, Achievements, and Future Directions.
Ban Qi Tay, Quentin Wright, Rahul Ladwa, Christopher Perry, Graham Leggatt

Vaccines (Basel)· May 2021

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Investigating T Cell Immunity in Cancer: Achievements and Prospects.
Zhen Zeng, Hui Yi Chew, Jazmina G Cruz, Graham R Leggatt, James W Wells

Int J Mol Sci· March 2021

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Increased lipid metabolism impairs NK cell function and mediates adaptation to the lymphoma environment.
Takumi Kobayashi, Pui Yeng Lam, Hui Jiang, Karolina Bednarska, Renee Gloury, Graham R Leggatt

Blood· December 2020

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HPV16 E7-Driven Epithelial Hyperplasia Promotes Impaired Antigen Presentation and Regulatory T-Cell Development.
Abate Assefa Bashaw, Siok M Teoh, Zewen K Tuong, Graham R Leggatt, Ian H Frazer

J Invest Dermatol· December 2019

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Recruitment of Antigen Presenting Cells to Skin Draining Lymph Node From HPV16E7-Expressing Skin Requires E7-Rb Interaction.
Paula Kuo, Siok Min Teoh, Zewen K Tuong, Graham R Leggatt, Stephen R Mattarollo

Front Immunol· November 2019

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Cytokine/chemokine profiles in squamous cell carcinoma correlate with precancerous and cancerous disease stage.
Zewen K Tuong, Andrew Lewandowski, Jennifer A Bridge, Jazmina L G Cruz, Miko Yamada, Graham R Leggatt

Sci Rep· November 2019

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NKT Cell-Driven Enhancement of Antitumor Immunity Induced by Clec9a-Targeted Tailorable Nanoemulsion.
Pui Yeng Lam, Takumi Kobayashi, Megan Soon, Bijun Zeng, Riccardo Dolcetti, Graham Leggatt

Cancer Immunol Res· June 2019

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An Ex Vivo Human Tumor Assay Shows Distinct Patterns of EGFR Trafficking in Squamous Cell Carcinoma Correlating to Therapeutic Outcomes.
Shannon R Joseph, Daniel Gaffney, Rachael Barry, Lingbo Hu, Blerida Banushi, Graham R Leggatt

J Invest Dermatol· January 2019

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The Role of CXCR3 and Its Chemokine Ligands in Skin Disease and Cancer.
Paula T Kuo, Zhen Zeng, Nazhifah Salim, Stephen Mattarollo, James W Wells, Graham R Leggatt

Front Med (Lausanne)· September 2018

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Therapeutic vaccination with 4-1BB co-stimulation eradicates mouse acute myeloid leukemia.
Daniel Kerage, Megan S F Soon, Brianna L Doff, Takumi Kobayashi, Michael D Nissen, Graham R Leggatt

Oncoimmunology· July 2018

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HPV16E7-Induced Hyperplasia Promotes CXCL9/10 Expression and Induces CXCR3 T-Cell Migration to Skin.
Paula Kuo, Zewen K Tuong, Siok Min Teoh, Ian H Frazer, Stephen R Mattarollo, Graham R Leggatt

J Invest Dermatol· June 2018

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Development of a polyclonal anti-dugong immunoglobulin G (IgG) antibody with evaluation of total plasma IgG in a living dugong (Dugong dugon) population.
Arthur Wong, Janet M Lanyon, Sara J McKee, Richard Linedale, Lucy Woolford, Graham R Leggatt

Vet Immunol Immunopathol· June 2018

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Modulation of antigen presenting cell functions during chronic HPV infection.
Abate Assefa Bashaw, Graham R Leggatt, Janin Chandra, Zewen K Tuong, Ian H Frazer

Papillomavirus Res· December 2017

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B cell lymphoma progression promotes the accumulation of circulating Ly6Clo monocytes with immunosuppressive activity.
Sara J McKee, Zewen K Tuong, Takumi Kobayashi, Brianna L Doff, Megan Sf Soon, Graham Leggatt

Oncoimmunology· December 2017

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Interferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity.
Purnima Bhat, Graham Leggatt, Nigel Waterhouse, Ian H Frazer

Cell Death Dis· June 2017

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HPV16-E7-Specific Activated CD8 T Cells in E7 Transgenic Skin and Skin Grafts.
Seyed Davoud Jazayeri, Paula T Kuo, Graham Robert Leggatt, Ian H Frazer

Front Immunol· May 2017

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Elevated frequencies of CD8 T cells expressing PD-1, CTLA-4 and Tim-3 within tumour from perineural squamous cell carcinoma patients.
Richard Linedale, Campbell Schmidt, Brigid T King, Annabelle G Ganko, Fiona Simpson, Graham R Leggatt

PLoS One· April 2017

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Control of B-cell lymphoma by therapeutic vaccination and acquisition of immune resistance is independent of direct tumour IFN-gamma signalling.
Rory Rearden, Amelia Sah, Brianna Doff, Takumi Kobayashi, Sara J McKee, Graham R Leggatt

Immunol Cell Biol· July 2016

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Galectin-1 is associated with poor prognosis in patients with cutaneous head and neck cancer with perineural spread.
Sharad Chawla, Timothy A Warren, Leesa F Wockner, Duncan L J Lambie, Ian S Brown, Graham R Leggatt

Cancer Immunol Immunother· February 2016

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Aurora A Is Critical for Survival in HPV-Transformed Cervical Cancer.
Brian Gabrielli, Fawzi Bokhari, Max V Ranall, Zay Yar Oo, Alexander J Stevenson, Graham Leggatt

Mol Cancer Ther· December 2015

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