Publications by authors named "Graham McVicker"

Claim this Profile
J
Joint single-cell profiling of Cas9 edits and transcriptomes reveals widespread off-target events and effects on gene expression.
Michael H Lorenzini, Brad Balderson, Karthyayani Sajeev, Aaron J Ho, Graham McVicker

bioRxiv· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Comprehensive molecular impact mapping of common and rare variants at GWAS loci.
Brad Balderson, Sanjana Tule, Mei-Lin Okino, William Jf Rieger, Sierra Corban, Graham McVicker

bioRxiv· June 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Multiomic QTL mapping reveals phenotypic complexity of GWAS loci and prioritizes putative causal variants.
Timothy D Arthur, Jennifer P Nguyen, Benjamin A Henson, Agnieszka D'Antonio-Chronowska, Jeffrey Jaureguy, Graham McVicker

Cell Genom· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
GenVarLoader: An accelerated dataloader for applying deep learning to personalized genomics.
David Laub, Aaron Ho, Jeff Jaureguy, Adam Klie, Rany M Salem, Graham McVicker

bioRxiv· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Analysis of single-cell CRISPR perturbations indicates that enhancers predominantly act multiplicatively.
Jessica L Zhou, Karthik Guruvayurappan, Shushan Toneyan, Hsiuyi V Chen, Aaron R Chen, Graham McVicker

Cell Genom· November 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Analysis of single-cell CRISPR perturbations indicates that enhancers act multiplicatively and provides limited evidence for epistatic-like interactions.
Jessica Zhou, Karthik Guruvayurappan, Shushan Toneyan, Hsiuyi V Chen, Aaron R Chen, Graham McVicker

bioRxiv· July 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Multi-omic QTL mapping in early developmental tissues reveals phenotypic and temporal complexity of regulatory variants underlying GWAS loci.
Timothy D Arthur, Jennifer P Nguyen, Agnieszka D'Antonio-Chronowska, Jeffrey Jaureguy, Nayara Silva, Graham McVicker

bioRxiv· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition.
Jessica L Zhou, Giordano de Guglielmo, Aaron J Ho, Marsida Kallupi, Narayan Pokhrel, Graham McVicker

Nat Neurosci· November 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Author Correction: Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition.
Jessica L Zhou, Giordano de Guglielmo, Aaron J Ho, Marsida Kallupi, Narayan Pokhrel, Graham McVicker

Nat Neurosci· November 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Deletion mapping of regulatory elements for GATA3 in T cells reveals a distal enhancer involved in allergic diseases.
Hsiuyi V Chen, Michael H Lorenzini, Shanna N Lavalle, Karthyayani Sajeev, Ariana Fonseca, Graham McVicker

Am J Hum Genet· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structural variants drive context-dependent oncogene activation in cancer.
Zhichao Xu, Dong-Sung Lee, Sahaana Chandran, Victoria T Le, Rosalind Bump, Graham McVicker

Nature· December 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Systematic discovery and functional dissection of enhancers needed for cancer cell fitness and proliferation.
Poshen B Chen, Patrick C Fiaux, Kai Zhang, Bin Li, Naoki Kubo, Graham McVicker

Cell Rep· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Allele-specific expression reveals genes with recurrent cis-regulatory alterations in high-risk neuroblastoma.
Arko Sen, Yuchen Huo, Jennifer Elster, Peter E Zage, Graham McVicker

Genome Biol· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma.
Arko Sen, Briana C Prager, Cuiqing Zhong, Donglim Park, Zhe Zhu, Graham McVicker

Cancer Res· February 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovering single nucleotide variants and indels from bulk and single-cell ATAC-seq.
Arya R Massarat, Arko Sen, Jeff Jaureguy, Sélène T Tyndale, Yi Fu, Graham McVicker

Nucleic Acids Res· August 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovering functional sequences with RELICS, an analysis method for CRISPR screens.
Patrick C Fiaux, Hsiuyi V Chen, Poshen B Chen, Aaron R Chen, Graham McVicker

PLoS Comput Biol· September 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
B
Brain cell type-specific enhancer-promoter interactome maps and diseaserisk association.
Alexi Nott, Inge R Holtman, Nicole G Coufal, Johannes C M Schlachetzki, Miao Yu, Graham McVicker

Science· November 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Impact of Genetic Polymorphisms on Human Immune Cell Gene Expression.
Benjamin J Schmiedel, Divya Singh, Ariel Madrigal, Alan G Valdovino-Gonzalez, Brandie M White, Graham McVicker

Cell· November 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A comparison of nucleosome organization in Drosophila cell lines.
Rebecca L Martin, John Maiorano, Greg J Beitel, John F Marko, Graham McVicker

PLoS One· September 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A Genomic Map of the Effects of Linked Selection in Drosophila.
Eyal Elyashiv, Shmuel Sattath, Tina T Hu, Alon Strutsovsky, Graham McVicker

PLoS Genet· August 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
W
WASP: allele-specific software for robust molecular quantitative trait locus discovery.
Bryce van de Geijn, Graham McVicker, Yoav Gilad, Jonathan K Pritchard

Nat Methods· November 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels.
Nicholas E Banovich, Xun Lan, Graham McVicker, Bryce van de Geijn, Jacob F Degner

PLoS Genet· September 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The chromatin architectural proteins HMGD1 and H1 bind reciprocally and have opposite effects on chromatin structure and gene regulation.
Narasimharao Nalabothula, Graham McVicker, John Maiorano, Rebecca Martin, Jonathan K Pritchard

BMC Genomics· February 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The genome shows its sensitive side.
Anil Raj, Graham McVicker

Nat Methods· January 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identification of genetic variants that affect histone modifications in human cells.
Graham McVicker, Bryce van de Geijn, Jacob F Degner, Carolyn E Cain, Nicholas E Banovich

Science· November 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis