Publications by authors named "Greg Brooke"

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Author Correction: PSIP1/LEDGF reduces R-loops at transcription sites to maintain genome integrity.
Sundarraj Jayakumar, Manthan Patel, Fanny Boulet, Hadicha Aziz, Greg N Brooke

Nat Commun· June 2024

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Nucleosome reorganisation in breast cancer tissues.
Divya R Jacob, Wilfried M Guiblet, Hulkar Mamayusupova, Mariya Shtumpf, Isabella Ciuta, Greg N Brooke

Clin Epigenetics· April 2024

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The antiviral potential of the antiandrogen enzalutamide and the viral-androgen signaling interplay in seasonal coronaviruses.
Oluwadamilola D Ogunjinmi, Tukur Abdullahi, Riaz-Ali Somji, Charlotte L Bevan, Wendy S Barclay, Greg N Brooke

J Med Virol· March 2024

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PSIP1/LEDGF reduces R-loops at transcription sites to maintain genome integrity.
Sundarraj Jayakumar, Manthan Patel, Fanny Boulet, Hadicha Aziz, Greg N Brooke

Nat Commun· January 2024

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Generation of magnetic biohybrid microrobots based on MSC.sTRAIL for targeted stem cell delivery and treatment of cancer.
Rebekah Anamarie Gundersen, Tianyuan Chu, Kiana Abolfathi, Serap Gokcen Dogan, Phoebe Elizabeth Blair, Greg Nicholas Brooke

Cancer Nanotechnol· May 2023

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A computational approach to identify efficient RNA cleaving 10-23 DNAzymes.
Angela C Pine, Greg N Brooke, Antonio Marco

NAR Genom Bioinform· March 2023

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Use of Antiandrogens as Therapeutic Agents in COVID-19 Patients.
Efstathios S Giotis, Emine Cil, Greg N Brooke

Viruses· December 2022

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Roles of steroid receptors in the lung and COVID-19.
Damien A Leach, Greg N Brooke, Charlotte L Bevan

Essays Biochem· December 2021

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Assessing Phototoxicity in a Mammalian Cell Line: How Low Levels of Blue Light Affect Motility in PC3 Cells.
Rana A Alghamdi, Marino Exposito-Rodriguez, Philip M Mullineaux, Greg N Brooke, Philippe P Laissue

Front Cell Dev Biol· December 2021

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Fas-threshold signalling in MSCs promotes pancreatic cancer progression and metastasis.
Andrea Mohr, Tianyuan Chu, Christopher T Clarkson, Greg N Brooke, Vladimir B Teif

Cancer Lett· October 2021

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The role of the p90 ribosomal S6 kinase family in prostate cancer progression and therapy resistance.
Ryan Cronin, Greg N Brooke, Filippo Prischi

Oncogene· June 2021

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Structural and functional modelling of SARS-CoV-2 entry in animal models.
Greg N Brooke, Filippo Prischi

Sci Rep· September 2020

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MSC.sTRAIL Has Better Efficacy than MSC.FL-TRAIL and in Combination with AKTi Blocks Pro-Metastatic Cytokine Production in Prostate Cancer Cells.
Andrea Mohr, Tianyuan Chu, Greg N Brooke, Ralf M Zwacka

Cancers (Basel)· April 2019

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Advances in genetics: widening our understanding of prostate cancer.
Angela C Pine, Flavia F Fioretti, Greg N Brooke, Charlotte L Bevan

F1000Res· July 2016

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Antiandrogens act as selective androgen receptor modulators at the proteome level in prostate cancer cells.
Greg N Brooke, Simon C Gamble, Michael A Hough, Shajna Begum, D Alwyn Dart

Mol Cell Proteomics· May 2015

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The co-chaperone p23 promotes prostate cancer motility and metastasis.
Laia Querol Cano, Derek N Lavery, Soraya Sin, Emma Spanjaard, Greg N Brooke

Mol Oncol· January 2015

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Phosphorylation of activating transcription factor-2 (ATF-2) within the activation domain is a key determinant of sensitivity to tamoxifen in breast cancer.
Bharath Rudraraju, Marjolein Droog, Tarek M A Abdel-Fatah, Wilbert Zwart, Athina Giannoudis, Greg N Brooke

Breast Cancer Res Treat· September 2014

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Engineered repressors are potent inhibitors of androgen receptor activity.
Greg N Brooke, Sue M Powell, Derek N Lavery, Jonathan Waxman, Laki Buluwela

Oncotarget· February 2014

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Characterisation of the androgen regulation of glycine N-methyltransferase in prostate cancer cells.
Silvia Ottaviani, Greg N Brooke, Ciara O'Hanlon-Brown, Jonathan Waxman, Simak Ali

J Mol Endocrinol· December 2013

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Circulating nucleic acids as biomarkers of prostate cancer.
Ailsa Sita-Lumsden, Claire E Fletcher, D Alwyn Dart, Greg N Brooke, Jonathan Waxman

Biomark Med· December 2013

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Role of the HSP90-associated cochaperone p23 in enhancing activity of the androgen receptor and significance for prostate cancer.
Vikash Reebye, Laia Querol Cano, Derek N Lavery, Greg N Brooke, Sue M Powell

Mol Endocrinol· October 2012

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Allosteric conversation in the androgen receptor ligand-binding domain surfaces.
Solène Grosdidier, Laia R Carbó, Víctor Buzón, Greg Brooke, Phuong Nguyen

Mol Endocrinol· July 2012

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FUS/TLS is a novel mediator of androgen-dependent cell-cycle progression and prostate cancer growth.
Greg N Brooke, Rachel L Culley, D Alwyn Dart, David J Mann, Luke Gaughan

Cancer Res· February 2011

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Pyrazino[1,2-a]indole-1,4-diones, simple analogues of gliotoxin, as selective inhibitors of geranylgeranyltransferase I.
David M Vigushin, Greg Brooke, David Willows, R Charles Coombes, Christopher J Moody

Bioorg Med Chem Lett· November 2003

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Cyclic acid anhydrides as a new class of potent, selective and non-peptidic inhibitors of geranylgeranyl transferase.
Charles M Marson, Alphonso S Rioja, Greg Brooke, R Charles Coombes, David M Vigushin

Bioorg Med Chem Lett· January 2002

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