Publications by authors named "Charles M Marson"

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A distal regulatory region of a class I human histone deacetylase.
Nicolas D Werbeck, Vaibhav Kumar Shukla, Micha B A Kunze, Havva Yalinca, Ruth B Pritchard, Charles M Marson

Nat Commun· July 2020

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Potent non-hydroxamate inhibitors of histone deacetylase-8: Role and scope of an isoindolin-2-yl linker with an α-amino amide as the zinc-binding unit.
Simon O R Greenwood, A W Edith Chan, D Flemming Hansen, Charles M Marson

Bioorg Med Chem Lett· March 2020

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Monocyclic Quinone Structure-Activity Patterns: Synthesis of Catalytic Inhibitors of Topoisomerase II with Potent Antiproliferative Activity.
Thomas M Waugh, John Masters, Abil E Aliev, Charles M Marson

ChemMedChem· January 2020

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Targeting TAO Kinases Using a New Inhibitor Compound Delays Mitosis and Induces Mitotic Cell Death in Centrosome Amplified Breast Cancer Cells.
Chuay-Yeng Koo, Caterina Giacomini, Marta Reyes-Corral, Yolanda Olmos, Ignatius A Tavares, Charles M Marson

Mol Cancer Ther· November 2017

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Pteridine-2,4-diamine derivatives as radical scavengers and inhibitors of lipoxygenase that can possess anti-inflammatory properties.
Eleni Pontiki, Dimitra Hadjipavlou-Litina, Alexandros Patsilinakos, Trang M Tran, Charles M Marson

Future Med Chem· July 2016

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Potent and Selective Inhibitors of Histone Deacetylase-3 Containing Chiral Oxazoline Capping Groups and a N-(2-Aminophenyl)-benzamide Binding Unit.
Charles M Marson, Christopher J Matthews, Stephen J Atkinson, Nermina Lamadema, N Shaun B Thomas

J Med Chem· September 2015

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The histone deacetylase inhibitor UCL67022 has potent activity in multiple myeloma and non-Hodgkin lymphoma pre-clinical models.
Lenushka Maharaj, Charles M Marson, Brian J Middleton, Alf S Rioja, Jackie Perry

Br J Haematol· October 2013

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Discovery of potent, isoform-selective inhibitors of histone deacetylase containing chiral heterocyclic capping groups and a N-(2-aminophenyl)benzamide binding unit.
Charles M Marson, Christopher J Matthews, Elena Yiannaki, Stephen J Atkinson, Peter E Soden

J Med Chem· August 2013

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Multicomponent and sequential organocatalytic reactions: diversity with atom-economy and enantiocontrol.
Charles M Marson

Chem Soc Rev· December 2012

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New and unusual scaffolds in medicinal chemistry.
Charles M Marson

Chem Soc Rev· November 2011

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Targeting the histamine H4 receptor.
Charles M Marson

Chem Rev· November 2011

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Histone deacetylase inhibitors: design, structure-activity relationships and therapeutic implications for cancer.
Charles M Marson

Anticancer Agents Med Chem· July 2009

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Effects of a selection of histone deacetylase inhibitors on mast cell activation and airway and colonic smooth muscle contraction.
El-Sayed K Assem, Kheng H Peh, Beatrice Y C Wan, Brian J Middleton, Jon Dines, Charles M Marson

Int Immunopharmacol· December 2008

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Thiostrepton selectively targets breast cancer cells through inhibition of forkhead box M1 expression.
Jimmy M-M Kwok, Stephen S Myatt, Charles M Marson, R Charles Coombes, Demetra Constantinidou

Mol Cancer Ther· July 2008

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A catalytic asymmetric protocol for the enantioselective synthesis of 3(2H)-furanones.
Charles M Marson, Esra Edaan, James M Morrell, Simon J Coles, Michael B Hursthouse

Chem Commun (Camb)· June 2007

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Structure-activity relationships of aryloxyalkanoic acid hydroxyamides as potent inhibitors of histone deacetylase.
Charles M Marson, Thevaki Mahadevan, Jon Dines, Stéphane Sengmany, James M Morrell

Bioorg Med Chem Lett· January 2007

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Synthesis of the penta-oxazole core of telomestatin in a convergent approach to poly-oxazole macrocycles.
Charles M Marson, Mona Saadi

Org Biomol Chem· November 2006

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Aromatic sulfide inhibitors of histone deacetylase based on arylsulfinyl-2,4-hexadienoic acid hydroxyamides.
Charles M Marson, Pascal Savy, Alphonso S Rioja, Thevaki Mahadevan, Catherine Mikol

J Med Chem· January 2006

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Enantioselective syntheses of trans-3,4-difluoropyrrolidines and investigation of their applications in catalytic asymmetric synthesis.
Charles M Marson, Robert C Melling

J Org Chem· November 2005

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Stereodefined and polyunsaturated inhibitors of histone deacetylase based on (2E,4E)-5-arylpenta-2,4-dienoic acid hydroxyamides.
Charles M Marson, Nawal Serradji, Alphonso S Rioja, Sebastien P Gastaud, John P Alao

Bioorg Med Chem Lett· May 2004

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Production of malodorous steroids from androsta-5,16-dienes and androsta-4,16-dienes by Corynebacteria and other human axillary bacteria.
Richard A Decréau, Charles M Marson, Kelvin E Smith, John M Behan

J Steroid Biochem Mol Biol· December 2003

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An asymmetric synthesis of aza analogues of the tricyclic skeleton of daphnane and the ABC ring system of phorbol.
Charles M Marson, Jennifer H Pink, David Hall, Michael B Hursthouse, Abdul Malik

J Org Chem· February 2003

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Cyclic acid anhydrides as a new class of potent, selective and non-peptidic inhibitors of geranylgeranyl transferase.
Charles M Marson, Alphonso S Rioja, Greg Brooke, R Charles Coombes, David M Vigushin

Bioorg Med Chem Lett· January 2002

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Stereocontrolled Routes to Bridged Ethers by Tandem Cyclizations.
Charles M Marson, Jon Campbell, Michael B Hursthouse, K M Abdul Malik

Angew Chem Int Ed Engl· May 1998

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