Publications by authors named "Pascal Savy"

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Addendum: Accurate structure prediction of biomolecular interactions with AlphaFold 3.
Josh Abramson, Jonas Adler, Jack Dunger, Richard Evans, Tim Green, Pascal Savy

Nature· December 2024

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Accurate structure prediction of biomolecular interactions with AlphaFold 3.
Josh Abramson, Jonas Adler, Jack Dunger, Richard Evans, Tim Green, Pascal Savy

Nature· June 2024

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Identification of N-sulfonyl-tetrahydroquinolines as RORc inverse agonists.
Benjamin P Fauber, Alberto Gobbi, Pascal Savy, Brenda Burton, Yuzhong Deng

Bioorg Med Chem Lett· October 2015

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Structure based design of novel 6,5 heterobicyclic mitogen-activated protein kinase kinase (MEK) inhibitors leading to the discovery of imidazo[1,5-a] pyrazine G-479.
Kirk D Robarge, Wendy Lee, Charles Eigenbrot, Mark Ultsch, Christian Wiesmann, Pascal Savy

Bioorg Med Chem Lett· October 2014

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Potent and highly selective benzimidazole inhibitors of PI3-kinase delta.
Jeremy M Murray, Zachary K Sweeney, Bryan K Chan, Mercedesz Balazs, Erin Bradley, Pascal P A Savy

J Med Chem· September 2012

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Discovery of novel PI3-kinase δ specific inhibitors for the treatment of rheumatoid arthritis: taming CYP3A4 time-dependent inhibition.
Brian S Safina, Stewart Baker, Matt Baumgardner, Paul M Blaney, Bryan K Chan, Pascal A Savy

J Med Chem· June 2012

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Discovery of novel allosteric mitogen-activated protein kinase kinase (MEK) 1,2 inhibitors possessing bidentate Ser212 interactions.
Robert A Heald, Philip Jackson, Pascal Savy, Mark Jones, Emanuela Gancia

J Med Chem· May 2012

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Identification and hit-to-lead exploration of a novel series of histamine H4 receptor inverse agonists.
Sue Cramp, Hazel J Dyke, Christopher Higgs, David E Clark, Matthew Gill, Pascal Savy

Bioorg Med Chem Lett· April 2010

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Aromatic sulfide inhibitors of histone deacetylase based on arylsulfinyl-2,4-hexadienoic acid hydroxyamides.
Charles M Marson, Pascal Savy, Alphonso S Rioja, Thevaki Mahadevan, Catherine Mikol

J Med Chem· January 2006

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Binding properties of oligonucleotides containing a modified 2'-deoxyuridine with a thymine ended linker to pair with 2'-deoxyadenosine.
Pascal Savy, Rachid Benhida, Jean Louis Fourrey, Rosalie Maurisse, Jian Sheng Sun

Bioorg Med Chem Lett· March 2002

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