Publications by authors named "Gregg V Crichlow"

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Updated resources for exploring experimentally-determined PDB structures and Computed Structure Models at the RCSB Protein Data Bank.
Stephen K Burley, Rusham Bhatt, Charmi Bhikadiya, Chunxiao Bi, Alison Biester, Gregg V Crichlow

Nucleic Acids Res· January 2025

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RCSB Protein Data Bank (RCSB.org): delivery of experimentally-determined PDB structures alongside one million computed structure models of proteins from artificial intelligence/machine learning.
Stephen K Burley, Charmi Bhikadiya, Chunxiao Bi, Sebastian Bittrich, Henry Chao, Gregg V Crichlow

Nucleic Acids Res· January 2023

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RCSB Protein Data bank: Tools for visualizing and understanding biological macromolecules in 3D.
Stephen K Burley, Charmi Bhikadiya, Chunxiao Bi, Sebastian Bittrich, Henry Chao, Gregg V Crichlow

Protein Sci· December 2022

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RCSB Protein Data Bank: Celebrating 50 years of the PDB with new tools for understanding and visualizing biological macromolecules in 3D.
Stephen K Burley, Charmi Bhikadiya, Chunxiao Bi, Sebastian Bittrich, Li Chen, Gregg V Crichlow

Protein Sci· January 2022

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RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences.
Stephen K Burley, Charmi Bhikadiya, Chunxiao Bi, Sebastian Bittrich, Li Chen, Gregg V Crichlow

Nucleic Acids Res· January 2021

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Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
Hsin-Hao T Hsiao, Gregg V Crichlow, James W Murphy, Ewa J Folta-Stogniew, Elias J Lolis

PLoS One· January 2021

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ISO-66, a novel inhibitor of macrophage migration, shows efficacy in melanoma and colon cancer models.
Kyriaki Ioannou, Kai Fan Cheng, Gregg V Crichlow, Anastasios I Birmpilis, Elias J Lolis

Int J Oncol· October 2014

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Structural interactions dictate the kinetics of macrophage migration inhibitory factor inhibition by different cancer-preventive isothiocyanates.
Gregg V Crichlow, Chengpeng Fan, Camille Keeler, Michael Hodsdon, Elias J Lolis

Biochemistry· September 2012

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Protein crystallization facilitated by molecularly imprinted polymers.
Emmanuel Saridakis, Sahir Khurshid, Lata Govada, Quan Phan, Daniel Hawkins, Gregg V Crichlow

Proc Natl Acad Sci U S A· July 2011

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Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.
Yoonsang Cho, Gregg V Crichlow, Jon J Vermeire, Lin Leng, Xin Du

Proc Natl Acad Sci U S A· June 2010

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Structural and kinetic analyses of macrophage migration inhibitory factor active site interactions.
Gregg V Crichlow, Jodi B Lubetsky, Lin Leng, Richard Bucala, Elias J Lolis

Biochemistry· January 2009

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Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition.
Gregg V Crichlow, Hongwen Zhou, Hsin-hao Hsiao, Kendra B Frederick, Maxime Debrosse

EMBO J· January 2008

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Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor.
Gregg V Crichlow, Kai Fan Cheng, Darrin Dabideen, Mahendar Ochani, Bayan Aljabari

J Biol Chem· August 2007

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Structure of an extended-spectrum class A beta-lactamase from Proteus vulgaris K1.
Michiyoshi Nukaga, Kayoko Mayama, Gregg V Crichlow, James R Knox

J Mol Biol· March 2002

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