Publications by authors named "Gregorio Encina"

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Enflicoxib for the long-term management of canine osteoarthritis-External validation of a population pharmacokinetic model in dogs with osteoarthritis.
Josep-Maria Cendrós, Marta Salichs, Gregorio Encina, Jose Miguel Vela, Josep Homedes

Front Vet Sci· October 2025

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Bispecific sigma-1 receptor antagonism and mu-opioid receptor partial agonism: WLB-73502, an analgesic with improved efficacy and safety profile compared to strong opioids.
Alba Vidal-Torres, Begoña Fernández-Pastor, Mónica García, Eva Ayet, Anna Cabot, Gregorio Encina

Acta Pharm Sin B· January 2023

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Results from two-year rodent oral carcinogenicity studies of cizolirtine, a substance-P and calcitonin gene-related peptide release modulator.
Antonio Guzmán, Araceli Tortajada, Ana-Paz Marín, Cristina Vila, Gregorio Encina

Regul Toxicol Pharmacol· July 2022

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Pharmacology of enflicoxib, a new coxib drug: Efficacy and dose determination by clinical and pharmacokinetic-guided approach for the treatment of osteoarthritis in dogs based on an acute arthritis induction model.
Josep-Maria Cendrós, Marta Salichs, Gregorio Encina, Jose Miguel Vela, Josep M Homedes

Vet Med Sci· January 2022

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Comparative Metabolism of Enflicoxib in Dogs, Rats, and Humans: Main Metabolites and Proposed Metabolic Pathways.
Josep Solà, Àngel Menargues, Josep Homedes, Marta Salichs, Maria Teresa Serafini, Gregorio Encina

Drug Metab Lett· January 2022

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Pharmacokinetics of enflicoxib in dogs: Effects of prandial state and repeated administration.
Josep Homedes, Marta Salichs, Josep Solà, Angel Menargues, Josep-Maria Cendrós, Gregorio Encina

J Vet Pharmacol Ther· November 2021

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Twenty six-week repeat dose oral rat toxicity study of cizolirtine, a substance-P and calcitonin gene-related peptide release modulator.
Antonio Guzmán, Gregorio Encina, Antonio R Fernández de Henestrosa, Cristina Vila, Araceli Tortajada

Regul Toxicol Pharmacol· June 2021

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Celecoxib-tramadol co-crystal: A Randomized 4-Way Crossover Comparative Bioavailability Study.
Jesús Cebrecos, James D Carlson, Gregorio Encina, Mounia Lahjou, Artur Sans

Clin Ther· June 2021

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Co-crystal of tramadol-celecoxib: preclinical and clinical evaluation of a novel analgesic.
Neus Gascon, Carmen Almansa, Manuel Merlos, José Miguel Vela, Gregorio Encina

Expert Opin Investig Drugs· May 2019

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Pharmacokinetics of Tramadol and Celecoxib in Japanese and Caucasian Subjects Following Administration of Co-Crystal of Tramadol-Celecoxib (CTC): A Randomised, Open-Label Study.
Helen Dooner, Gill Mundin, Sabine Mersmann, Carla Bennett, Ulrike Lorch, Gregorio Encina

Eur J Drug Metab Pharmacokinet· February 2019

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The Effect of Food on Tramadol and Celecoxib Bioavailability Following Oral Administration of Co-Crystal of Tramadol-Celecoxib (CTC): A Randomised, Open-Label, Single-Dose, Crossover Study in Healthy Volunteers.
Gregorio Encina, Mercedes Encabo, Marisol Escriche, Mounia Lahjou, Eric Sicard

Clin Drug Investig· September 2018

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Pharmacokinetics of multiple doses of co-crystal of tramadol-celecoxib: findings from a four-way randomized open-label phase I clinical trial.
Sebastián Videla, Mounia Lahjou, Anna Vaqué, Mariano Sust, Marisol Escriche, Gregorio Encina

Br J Clin Pharmacol· January 2018

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Single-dose pharmacokinetics of co-crystal of tramadol-celecoxib: Results of a four-way randomized open-label phase I clinical trial in healthy subjects.
Sebastián Videla, Mounia Lahjou, Anna Vaqué, Mariano Sust, Mercedes Encabo, Gregorio Encina

Br J Clin Pharmacol· December 2017

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Pharmacokinetic dose proportionality between two strengths (12.5 mg and 25 mg) of doxylamine hydrogen succinate film-coated tablets in fasting state: a single-dose, randomized, two-period crossover study in healthy volunteers.
Sebastián Videla, Jesús Cebrecos, Mounia Lahjou, France Wagner, Pascal Guibord, Gregorio Encina

Drugs R D· June 2013

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Safety, tolerability and pharmacokinetics of single and multiple doses of a novel sigma-1 receptor antagonist in three randomized phase I studies.
Montserrat Abadias, Marisol Escriche, Anna Vaqué, Mariano Sust, Gregorio Encina

Br J Clin Pharmacol· January 2013

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Food effects on the pharmacokinetics of doxylamine hydrogen succinate 25 mg film-coated tablets: a single-dose, randomized, two-period crossover study in healthy volunteers.
Sebastián Videla, Mounia Lahjou, Pascal Guibord, Zhengguo Xu, Carles Tolrà, Gregorio Encina

Drugs R D· December 2012

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Enantioselective HPLC determination of E-6087, a new COX-2 inhibitor, in human plasma: Validation and pharmacokinetic application.
Leonardo Salgado, Gregorio Encina, Ramón Farran, Santiago Puig, Luis Martínez

Chirality· May 2004

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