Publications by authors named "Gregory D Cuny"

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Sensory neuron-expressed FGF13 controls nociceptive signaling in diabetic neuropathy models.
Aditya K Singh, Matteo Bernabucci, Nolan M Dvorak, Zahra Haghighijoo, Jessica Di Re, Gregory D Cuny

J Clin Invest· July 2025

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Inhibition of the GSK3β/Nav1.6 complex suppresses early-stage Alzheimer's hyperexcitability.
Timothy John Baumgartner, Manuel Silva-Pérez, Zahra Haghighijoo, Nolan Michael Dvorak, Aditya Kumar Singh, Gregory D Cuny

Alzheimers Dement· July 2025

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Role of the Mobile Active Site Flap in IMP Dehydrogenase Inhibitor Binding.
Xingyou Wang, Masha M Rosenberg, Youngchang Kim, Natalia Maltseva, Gregory D Cuny

ACS Infect Dis· February 2025

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Pyridopyrimidinones as a new chemotype of calcium dependent protein kinase 1 (CDPK1) inhibitors for Cryptosporidium.
Elise Waldron-Young, Wissarut Wijitrmektong, Ryan Choi, Grant R Whitman, Matthew A Hulverson, Gregory D Cuny

Mol Biochem Parasitol· December 2024

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Necroptosis blockade prevents lung injury in severe influenza.
Avishekh Gautam, David F Boyd, Sameer Nikhar, Ting Zhang, Ioannis Siokas, Gregory D Cuny

Nature· April 2024

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A small molecule exerts selective antiviral activity by targeting the human cytomegalovirus nuclear egress complex.
Han Chen, Ming F Lye, Christoph Gorgulla, Scott B Ficarro, Gregory D Cuny

PLoS Pathog· November 2023

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Structure-activity relationship of BMS906024 derivatives for Cryptosporidium parvum growth inhibition.
Seungheon Lee, Melissa S Love, Ramkumar Modukuri, Arnab K Chatterjee, Lauren Huerta, Gregory D Cuny

Bioorg Med Chem Lett· June 2023

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Nonhydrolyzable d‑phenylalanine-benzoxazole derivatives retain antitubercular activity.
Michael J Pepi, Shibin Chacko, Nicole Kopetz, Helena I M Boshoff, Gregory D Cuny

Bioorg Med Chem Lett· January 2023

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An Immunconjugate Vaccine Alters Distribution and Reduces the Antinociceptive, Behavioral and Physiological Effects of Fentanyl in Male and Female Rats.
Colin N Haile, Miah D Baker, Sergio A Sanchez, Carlos A Lopez Arteaga, Anantha L Duddupudi, Gregory D Cuny

Pharmaceutics· October 2022

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A d-Phenylalanine-Benzoxazole Derivative Reveals the Role of the Essential Enzyme Rv3603c in the Pantothenate Biosynthetic Pathway of .
Michael J Pepi, Shibin Chacko, Gary M Marqus, Vinayak Singh, Zhe Wang, Gregory D Cuny

ACS Infect Dis· February 2022

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Expanding Benzoxazole-Based Inosine 5'-Monophosphate Dehydrogenase (IMPDH) Inhibitor Structure-Activity As Potential Antituberculosis Agents.
Shibin Chacko, Helena I M Boshoff, Vinayak Singh, Davide M Ferraris, Deviprasad R Gollapalli, Gregory D Cuny

J Med Chem· December 2021

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The Enzymatic Activity of Inosine 5'-Monophosphate Dehydrogenase May Not Be a Vulnerable Target for Infections.
Gyan Modi, Gary M Marqus, Mohana Rao Vippila, Deviprasad R Gollapalli, Youngchang Kim, Gregory D Cuny

ACS Infect Dis· November 2021

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Development of Rofecoxib-Based Fluorescent Probes and Investigations on Their Solvatochromism, AIE Activity, Mechanochromism, and COX-2-Targeted Bioimaging.
Lijun Xie, Renfu Li, Biyun Zheng, Zuoxu Xie, Xuefen Fang, Gregory D Cuny

Anal Chem· September 2021

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Syntheses of Gymnothespirolignans B and C and Non-natural Isomer 9-Epi-gymnothespirolignan B.
Ghada Ali, Gregory D Cuny

J Org Chem· August 2021

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Targeted Degradation of the Oncogenic Phosphatase SHP2.
Vidyasiri Vemulapalli, Katherine A Donovan, Tom C M Seegar, Julia M Rogers, Munhyung Bae, Gregory D Cuny

Biochemistry· August 2021

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Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor.
Tom Delanghe, Jon Huyghe, Seungheon Lee, Dario Priem, Samya Van Coillie, Gregory D Cuny

Cell Death Dis· July 2021

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8-, 9-, and 11-Aryloxy Dimeric Aporphines and Their Pharmacological Activities.
Ghada Ali, Gregory D Cuny

Molecules· July 2021

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Fentanyl conjugate vaccine by injected or mucosal delivery with dmLT or LTA1 adjuvants implicates IgA in protection from drug challenge.
Addison E Stone, Sarah E Scheuermann, Colin N Haile, Gregory D Cuny, Marcela Lopez Velasquez

NPJ Vaccines· May 2021

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Design of pyrido[2,3-d]pyrimidin-7-one inhibitors of receptor interacting protein kinase-2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling.
Sameer Nikhar, Ioannis Siokas, Lisa Schlicher, Seungheon Lee, Mads Gyrd-Hansen, Gregory D Cuny

Eur J Med Chem· April 2021

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One-Step Transformation from Rofecoxib to a COX-2 NIR Probe for Human Cancer Tissue/Organoid Targeted Bioimaging.
Lijun Xie, Renfu Li, Biyun Zheng, Zuoxu Xie, Xuefen Fang, Gregory D Cuny

ACS Appl Bio Mater· March 2021

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RIPK protein kinase family: Atypical lives of typical kinases.
Gregory D Cuny, Alexei Degterev

Semin Cell Dev Biol· January 2021

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Mycophenolic anilides as broad specificity inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitors.
Seungheon Lee, Angela F Ku, Mohana Rao Vippila, Yong Wang, Minjia Zhang, Gregory D Cuny

Bioorg Med Chem Lett· December 2020

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Receptor-interacting protein kinase 2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling inhibitors based on a 3,5-diphenyl-2-aminopyridine scaffold.
Chalada Suebsuwong, Bing Dai, Daniel M Pinkas, Anantha Lakshmi Duddupudi, Li Li, Gregory D Cuny

Eur J Med Chem· August 2020

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Hypervalent Iodine Mediated Oxidative Cyclization of Acrylamide -Carbamates to 5,5-Disubstituted Oxazolidine-2,4-diones.
Anantha Lakshmi Duddupudi, Pankaj Pandey, Hien Vo, Colin L Welsh, Robert J Doerksen, Gregory D Cuny

J Org Chem· June 2020

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Synthesis of the Tetracyclic Framework of Polycyclic Spiro Lignan Natural Products.
Ghada Ali, Gregory D Cuny

ACS Omega· April 2020

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