Publications by authors named "Gregory Driessens"

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TIGIT inhibition and lenalidomide synergistically promote antimyeloma immune responses after stem cell transplantation in mice.
Simone A Minnie, Olivia G Waltner, Kathleen S Ensbey, Stuart D Olver, Alika D Collinge, Gregory Driessens

J Clin Invest· February 2023

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Restoration of T-cell Effector Function, Depletion of Tregs, and Direct Killing of Tumor Cells: The Multiple Mechanisms of Action of a-TIGIT Antagonist Antibodies.
Julie Preillon, Julia Cuende, Virginie Rabolli, Lucile Garnero, Marjorie Mercier, Gregory Driessens

Mol Cancer Ther· January 2021

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Inhibition of Tryptophan-Dioxygenase Activity Increases the Antitumor Efficacy of Immune Checkpoint Inhibitors.
Florence Schramme, Stefano Crosignani, Kim Frederix, Delia Hoffmann, Luc Pilotte, Gregory Driessens

Cancer Immunol Res· January 2020

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Characterization of the Selective Indoleamine 2,3-Dioxygenase-1 (IDO1) Catalytic Inhibitor EOS200271/PF-06840003 Supports IDO1 as a Critical Resistance Mechanism to PD-(L)1 Blockade Therapy.
Bruno Gomes, Gregory Driessens, Derek Bartlett, Danying Cai, Sandra Cauwenberghs

Mol Cancer Ther· December 2018

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Deciphering tumor growth by clonal analysis.
Gregory Driessens

Crit Rev Oncog· December 2014

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SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma.
Soufiane Boumahdi, Gregory Driessens, Gaelle Lapouge, Sandrine Rorive, Dany Nassar

Nature· July 2014

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Conditional deletion of PTEN in peripheral T cells augments TCR-mediated activation but does not abrogate CD28 dependency or prevent anergy induction.
Frederick L Locke, Yuan-yuan Zha, Yan Zheng, Gregory Driessens, Thomas F Gajewski

J Immunol· August 2013

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Transcriptional regulator early growth response gene 2 (Egr2) is required for T cell anergy in vitro and in vivo.
Yan Zheng, Yuanyuan Zha, Gregory Driessens, Frederick Locke, Thomas F Gajewski

J Exp Med· November 2012

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Defining the mode of tumour growth by clonal analysis.
Gregory Driessens, Benjamin Beck, Amélie Caauwe, Benjamin D Simons, Cédric Blanpain

Nature· August 2012

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Long live sox2: sox2 lasts a lifetime.
Grégory Driessens, Cédric Blanpain

Cell Stem Cell· October 2011

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A vascular niche and a VEGF-Nrp1 loop regulate the initiation and stemness of skin tumours.
Benjamin Beck, Gregory Driessens, Steven Goossens, Khalil Kass Youssef, Anna Kuchnio

Nature· October 2011

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Development of a successful antitumor therapeutic model combining in vivo dendritic cell vaccination with tumor irradiation and intratumoral GM-CSF delivery.
Gregory Driessens, Lise Nuttin, Alain Gras, Julie Maetens, Stephane Mievis

Cancer Immunol Immunother· February 2011

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Beta-catenin inhibits T cell activation by selective interference with linker for activation of T cells-phospholipase C-γ1 phosphorylation.
Gregory Driessens, Yan Zheng, Frederick Locke, Judy L Cannon, Fotini Gounari

J Immunol· January 2011

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Beta-catenin does not regulate memory T cell phenotype.
Gregory Driessens, Yan Zheng, Thomas F Gajewski

Nat Med· May 2010

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A designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based library.
Zoltan Takacs, Megan Toups, Astrid Kollewe, Erik Johnson, Luis G Cuello, Gregory Driessens

Proc Natl Acad Sci U S A· December 2009

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Costimulatory and coinhibitory receptors in anti-tumor immunity.
Gregory Driessens, Justin Kline, Thomas F Gajewski

Immunol Rev· May 2009

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Synergy between dendritic cells and GM-CSF-secreting tumor cells for the treatment of a murine renal cell carcinoma.
Gregory Driessens, Paul Hoffmann, Michael Pouwels, Alexandre Zlotta, Claude Schulman

J Immunother· April 2009

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Therapeutic efficacy of antitumor dendritic cell vaccinations correlates with persistent Th1 responses, high intratumor CD8+ T cell recruitment and low relative regulatory T cell infiltration.
Gregory Driessens, Laurence Gordower, Lise Nuttin, Patrick Stordeur, Didier Blocklet

Cancer Immunol Immunother· December 2008

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Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells.
Candace M Cham, Gregory Driessens, James P O'Keefe, Thomas F Gajewski

Eur J Immunol· September 2008

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15-Deoxy-12,14-prostaglandin J2 inhibits interferon gamma induced MHC class II but not class I expression on ARPE cells through a PPAR gamma independent mechanism.
François Willermain, Simon Dulku, Nathalie Suarez Gonzalez, Daniel Blero, Gregory Driessens

Prostaglandins Other Lipid Mediat· September 2006

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Highly successful therapeutic vaccinations combining dendritic cells and tumor cells secreting granulocyte macrophage colony-stimulating factor.
Gregory Driessens, Malika Hamdane, Vincent Cool, Thierry Velu, Catherine Bruyns

Cancer Res· November 2004

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Assessment of in vivo chemotherapy-induced DNA damage in a p53-mutated rat tumor by micronuclei assay.
Gregory Driessens, Laura Harsan, Patrick Browaeys, Xenofon Giannakopoulos, Thierry Velu

Ann N Y Acad Sci· December 2003

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