Publications by authors named "Gregory Flynn"

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Using Innovative Software to Address the Puzzle of Sustainable Workforce Stability.
Kelly M Kester, Joseph Kelly, Mary Lindsay, Gregory Flynn, Jill Engel

J Nurs Adm· July 2025

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Implementing AACN's Healthy Work Environment Framework in an Intensive Care Unit.
Kelly Kester, Heather Pena, Catherine Shuford, Corrie Hansen, Jason Stokes, Gregory Flynn

Am J Crit Care· November 2021

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Glycan engineering reveals interrelated effects of terminal galactose and core fucose on antibody-dependent cell-mediated cytotoxicity.
Qingchun Zhang, Marisa K Joubert, Alla Polozova, Ronandro De Guzman, Kamala Lakamsani, Gregory C Flynn

Biotechnol Prog· November 2020

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Use of In Vitro Assays to Assess Immunogenicity Risk of Antibody-Based Biotherapeutics.
Marisa K Joubert, Meghana Deshpande, Jane Yang, Helen Reynolds, Christine Bryson, Gregory C Flynn

PLoS One· August 2017

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Evaluating Immunogenicity Risk Due to Host Cell Protein Impurities in Antibody-Based Biotherapeutics.
Vibha Jawa, Marisa K Joubert, Qingchun Zhang, Meghana Deshpande, Suminda Hapuarachchi, Gregory C Flynn

AAPS J· November 2016

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Development of advanced host cell protein enrichment and detection strategies to enable process relevant spike challenge studies.
Ryan G Soderquist, Mihaela Trumbo, Roger A Hart, Qingchun Zhang, Gregory C Flynn

Biotechnol Prog· May 2016

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Effect of high mannose glycan pairing on IgG antibody clearance.
Yaoqing Diana Liu, Gregory C Flynn

Biologicals· May 2016

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Characterization of the co-elution of host cell proteins with monoclonal antibodies during protein A purification.
Qingchun Zhang, Andrew M Goetze, Huanchun Cui, Jenna Wylie, Ben Tillotson, Gregory C Flynn

Biotechnol Prog· May 2016

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Comprehensive tracking of host cell proteins during monoclonal antibody purifications using mass spectrometry.
Qingchun Zhang, Andrew M Goetze, Huanchun Cui, Jenna Wylie, Steve Trimble, Gregory C Flynn

MAbs· May 2015

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Impact of glycation on antibody clearance.
Jane Yang, Ronya Primack, Mike Frohn, Wei Wang, Peng Luan, Gregory C Flynn

AAPS J· January 2015

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Investigation of antibody disulfide reduction and re-oxidation and impact to biological activities.
Tian Wang, Yaoqing Diana Liu, Bing Cai, Gang Huang, Gregory C Flynn

J Pharm Biomed Anal· January 2015

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Protected hinge in the immunoglobulin G2-A2 disulfide isoform.
Yaoqing Diana Liu, Robert Y-T Chou, Thomas M Dillon, Leszek Poppe, Chris Spahr, Gregory C Flynn

Protein Sci· December 2014

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Profiling the effects of process changes on residual host cell proteins in biotherapeutics by mass spectrometry.
Matthew R Schenauer, Gregory C Flynn, Andrew M Goetze

Biotechnol Prog· May 2014

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Assessment of naturally occurring covalent and total dimer levels in human IgG1 and IgG2.
Jane Yang, Andrew M Goetze, Gregory C Flynn

Mol Immunol· March 2014

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Monoclonal antibody disulfide reduction during manufacturing: Untangling process effects from product effects.
Katariina M Hutterer, Robert W Hong, Jonathon Lull, Xiaoyang Zhao, Tian Wang, Gregory C Flynn

MAbs· January 2014

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Cysteine racemization on IgG heavy and light chains.
Qingchun Zhang, Gregory C Flynn

J Biol Chem· November 2013

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IgG2 disulfide isoform conversion kinetics.
Yaoqing Diana Liu, Tian Wang, Robert Chou, Louise Chen, Gunasekaran Kannan, Gregory C Flynn

Mol Immunol· June 2013

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IgG1 thioether bond formation in vivo.
Qingchun Zhang, Matthew R Schenauer, John D McCarter, Gregory C Flynn

J Biol Chem· June 2013

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Evaluation of protein disulfide conversion in vitro using a continuous flow dialysis system.
Xinzhao Grace Jiang, Tian Wang, Oliver Kaltenbrunner, Kenneth Chen, Gregory C Flynn

Anal Biochem· January 2013

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Identification and quantification of host cell protein impurities in biotherapeutics using mass spectrometry.
Matthew R Schenauer, Gregory C Flynn, Andrew M Goetze

Anal Biochem· September 2012

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Rates and impact of human antibody glycation in vivo.
Andrew M Goetze, Y Diana Liu, Thomas Arroll, Lily Chu, Gregory C Flynn

Glycobiology· February 2012

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Rapid LC-MS screening for IgG Fc modifications and allelic variants in blood.
Andrew M Goetze, Zhongqi Zhang, Ling Liu, Frederick W Jacobsen, Gregory C Flynn

Mol Immunol· October 2011

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High-mannose glycans on the Fc region of therapeutic IgG antibodies increase serum clearance in humans.
Andrew M Goetze, Y Diana Liu, Zhongqi Zhang, Bhavana Shah, Edward Lee, Gregory C Flynn

Glycobiology· July 2011

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A high-throughput microchip-based glycan screening assay for antibody cell culture samples.
Jeremy Primack, Gregory C Flynn, Hai Pan

Electrophoresis· May 2011

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N-terminal glutamate to pyroglutamate conversion in vivo for human IgG2 antibodies.
Y Diana Liu, Andrew M Goetze, Randal B Bass, Gregory C Flynn

J Biol Chem· April 2011

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