Publications by authors named "Gregory Hoeker"

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Hypernatremia Enhances Transient Outward Potassium and Late Sodium Currents in a Mouse Model of Long QT Syndrome Type 3.
Xiaobo Wu, Sharon A Swanger, Gregory S Hoeker, Rowan Maisonneuve, Peter Carmeliet

bioRxiv· December 2025

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Age-Associated Perinexal Narrowing Masks Consequences of Sodium Channel Gain of Function in Guinea Pig Hearts.
Xiaobo Wu, David Ryan King, Gregory S Hoeker, Xiaoping Wan, Isabelle Deschenes

JACC Clin Electrophysiol· May 2025

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Flecainide sensitizes conduction to hyponatremia through an ephaptic mechanism.
William P Adams, Gregory S Hoeker, Steven Poelzing

Heart Rhythm· April 2025

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Sequence-Dependent Repolarization Is Modulated by Endogenous Action Potential Duration Gradients Rather Than Electrical Coupling in Ventricular Myocardium.
Grace A Blair, Madeline Depman, William P Adams, Rowan O Maisonneuve, Gregory S Hoeker

J Am Heart Assoc· January 2025

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Reconstructing ventricular cardiomyocyte dynamics and parameter estimation using data assimilation.
Mario J Mendez, Elizabeth M Cherry, Gregory S Hoeker, Steven Poelzing, Seth H Weinberg

Biophys J· December 2024

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Mannitol and hyponatremia regulate cardiac ventricular conduction in the context of sodium channel loss of function.
Grace A Blair, Xiaobo Wu, Chandra Bain, Mark Warren, Gregory S Hoeker

Am J Physiol Heart Circ Physiol· March 2024

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Acute Adenoviral Infection Elicits an Arrhythmogenic Substrate Prior to Myocarditis.
Rachel L Padget, Michael J Zeitz, Grace A Blair, Xiaobo Wu, Michael D North, Gregory S Hoeker

Circ Res· March 2024

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Extracellular Perinexal Separation Is a Principal Determinant of Cardiac Conduction.
William P Adams, Tristan B Raisch, Yajun Zhao, Rafael Davalos, Sarah Barrett, Gregory S Hoeker

Circ Res· September 2023

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Reevaluating methods reporting practices to improve reproducibility: an analysis of methodological rigor for the Langendorff whole heart technique.
D Ryan King, Kathryn M Hardin, Gregory S Hoeker, Steven Poelzing

Am J Physiol Heart Circ Physiol· September 2022

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Hypernatremia and intercalated disc edema synergistically exacerbate long-QT syndrome type 3 phenotype.
Xiaobo Wu, Gregory S Hoeker, Grace A Blair, D Ryan King, Robert G Gourdie

Am J Physiol Heart Circ Physiol· December 2021

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The conduction velocity-potassium relationship in the heart is modulated by sodium and calcium.
D Ryan King, Michael Entz, Grace A Blair, Ian Crandell, Alexandra L Hanlon, Gregory S Hoeker

Pflugers Arch· March 2021

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Elevated perfusate [Na] increases contractile dysfunction during ischemia and reperfusion.
D Ryan King, Rachel L Padget, Justin Perry, Gregory Hoeker, James W Smyth

Sci Rep· October 2020

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Attenuating loss of cardiac conduction during no-flow ischemia through changes in perfusate sodium and calcium.
Gregory S Hoeker, Carissa C James, Allison N Tegge, Robert G Gourdie, James W Smyth

Am J Physiol Heart Circ Physiol· August 2020

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Modulating cardiac conduction during metabolic ischemia with perfusate sodium and calcium in guinea pig hearts.
Sharon A George, Gregory Hoeker, Patrick J Calhoun, Michael Entz, Tristan B Raisch

Am J Physiol Heart Circ Physiol· April 2019

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The adhesion function of the sodium channel beta subunit (β1) contributes to cardiac action potential propagation.
Rengasayee Veeraraghavan, Gregory S Hoeker, Anita Alvarez-Laviada, Daniel Hoagland, Xiaoping Wan

Elife· August 2018

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Electrophysiologic effects of the IK1 inhibitor PA-6 are modulated by extracellular potassium in isolated guinea pig hearts.
Gregory S Hoeker, Mark A Skarsfeldt, Thomas Jespersen, Steven Poelzing

Physiol Rep· January 2017

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Reduced Arrhythmia Inducibility With Calcium/Calmodulin-dependent Protein Kinase II Inhibition in Heart Failure Rabbits.
Gregory S Hoeker, Mohamed A Hanafy, Robert A Oster, Donald M Bers, Steven M Pogwizd

J Cardiovasc Pharmacol· March 2016

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Sex differences in β-adrenergic responsiveness of action potentials and intracellular calcium handling in isolated rabbit hearts.
Gregory S Hoeker, Ashleigh R Hood, Rodolphe P Katra, Steven Poelzing, Steven M Pogwizd

PLoS One· January 2016

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Sodium channels in the Cx43 gap junction perinexus may constitute a cardiac ephapse: an experimental and modeling study.
Rengasayee Veeraraghavan, Joyce Lin, Gregory S Hoeker, James P Keener, Robert G Gourdie

Pflugers Arch· October 2015

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Moving beyond the reductionist approach-Time to put the pieces back together in a broken (infarcted) heart.
Gregory S Hoeker, Steven Poelzing

Heart Rhythm· January 2015

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Spontaneous calcium release in tissue from the failing canine heart.
Gregory S Hoeker, Rodolphe P Katra, Lance D Wilson, Bradley N Plummer, Kenneth R Laurita

Am J Physiol Heart Circ Physiol· October 2009

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Aldosterone blockade attenuates development of an electrophysiological substrate associated with ventricular tachyarrhythmias in heart failure.
Bruce S Stambler, Kenneth R Laurita, Sunil C Shroff, Gregory Hoeker, Nichole L Martovitz

Heart Rhythm· June 2009

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Heart failure enhances susceptibility to arrhythmogenic cardiac alternans.
Lance D Wilson, Darwin Jeyaraj, Xiaoping Wan, Gregory S Hoeker, Tamer H Said

Heart Rhythm· February 2009

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Imaging cellular calcium dysfunction in the heart using multi-modal optical mapping.
Gregory S Hoeker, Rodolphe P Katra, Kenneth R Laurita

Conf Proc IEEE Eng Med Biol Soc· March 2008

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Ryanodine receptor dysfunction and triggered activity in the heart.
Rodolphe P Katra, Toshiyuki Oya, Gregory S Hoeker, Kenneth R Laurita

Am J Physiol Heart Circ Physiol· May 2007

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