Publications by authors named "Gregory Merz"

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Developing Topics.
Vishnu Vijayan, Gregory Merz, Athena Quddus, Andrew P Longhini, Michael Vigers

Alzheimers Dement· December 2025

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Basic Science and Pathogenesis.
Sarah Kaufman, Jannis Bücking, Rudra Bose, Sarah Hoyle, Abi Wee, Gregory Merz

Alzheimers Dement· December 2025

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design of semisynthetic protein nanopores.
Lee Schnaider, A Katherine Hatstat, Alistair J Scott, Sophia K Tan, Richard G Hambley, Gregory E Merz

bioRxiv· September 2025

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Structure-specific Mini-Prion Model for Alzheimer's Disease Tau Fibrils.
Vishnu Vijayan, Gregory E Merz, Karen Tsay, Andrew P Longhini, Samuel Lobo

bioRxiv· June 2025

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Cryo-EM structure of a novel α-synuclein filament subtype from multiple system atrophy.
Nicholas L Yan, Francisco Candido, Eric Tse, Arthur A Melo, Stanley B Prusiner, Gregory E Merz

FEBS Lett· January 2025

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Cryo-EM structures reveal tau filaments from Down syndrome adopt Alzheimer's disease fold.
Ujjayini Ghosh, Eric Tse, Hyunjun Yang, Marie Shi, Christoffer D Caro, Gregory E Merz

Acta Neuropathol Commun· June 2024

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Cryo-EM Structures Reveal Tau Filaments from Down Syndrome Adopt Alzheimer's Disease Fold.
Ujjayini Ghosh, Eric Tse, Hyunjun Yang, Marie Shi, Christoffer D Carlo, Gregory E Merz

bioRxiv· May 2024

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Stacked binding of a PET ligand to Alzheimer's tau paired helical filaments.
Gregory E Merz, Matthew J Chalkley, Sophia K Tan, Eric Tse, Joanne Lee

Nat Commun· May 2023

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Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps.
Soumya G Remesh, Gregory E Merz, Axel F Brilot, Un Seng Chio, Alexandrea N Rizo

Structure· March 2023

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The E46K mutation modulates α-synuclein prion replication in transgenic mice.
Sara A M Holec, Jisoo Lee, Abby Oehler, Lyn Batia, Aryanna Wiggins-Gamble, Gregory E Merz

PLoS Pathog· December 2022

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Aβ and Tau Prions Causing Alzheimer's Disease.
Carlo Condello, Gregory E Merz, Atsushi Aoyagi, William F DeGrado, Stanley B Prusiner

Methods Mol Biol· November 2022

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Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps.
Soumya G Remesh, Gregory E Merz, Axel F Brilot, Un Seng Chio, Alexandrea N Rizo

bioRxiv· August 2022

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CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.
Meghna Gupta, Caleigh M Azumaya, Michelle Moritz, Sergei Pourmal, Amy Diallo, Gregory E Merz

bioRxiv· May 2021

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CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.
Meghna Gupta, Caleigh M Azumaya, Michelle Moritz, Sergei Pourmal, Amy Diallo, Gregory E Merz

Res Sq· May 2021

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Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking.
Marion Schuller, Galen J Correy, Stefan Gahbauer, Daren Fearon, Taiasean Wu, Gregory E Merz

Sci Adv· April 2021

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Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
David E Gordon, Joseph Hiatt, Mehdi Bouhaddou, Veronica V Rezelj, Svenja Ulferts, Gregory E Merz

Science· December 2020

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An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Michael Schoof, Bryan Faust, Reuben A Saunders, Smriti Sangwan, Veronica Rezelj, Gregory E Merz

Science· December 2020

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Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking.
Marion Schuller, Galen J Correy, Stefan Gahbauer, Daren Fearon, Taiasean Wu, Gregory E Merz

bioRxiv· November 2020

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An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation.
Michael Schoof, Bryan Faust, Reuben A Saunders, Smriti Sangwan, Veronica Rezelj, Gregory E Merz

bioRxiv· August 2020

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Site-Specific Incorporation of a Cu Spin Label into Proteins for Measuring Distances by Pulsed Dipolar Electron Spin Resonance Spectroscopy.
Gregory E Merz, Peter P Borbat, Alise R Muok, Madhur Srivastava, David N Bunck

J Phys Chem B· October 2018

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CK1/Doubletime activity delays transcription activation in the circadian clock.
Deniz Top, Jenna L O'Neil, Gregory E Merz, Kritika Dusad, Brian R Crane

Elife· April 2018

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Copper-based pulsed dipolar ESR spectroscopy as a probe of protein conformation linked to disease states.
Gregory E Merz, Peter P Borbat, Ashley J Pratt, Elizabeth D Getzoff, Jack H Freed

Biophys J· October 2014

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Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypes.
Ashley J Pratt, David S Shin, Gregory E Merz, Robert P Rambo, W Andrew Lancaster

Proc Natl Acad Sci U S A· October 2014

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Stability of single-nucleotide bulge loops embedded in a GAAA RNA hairpin stem.
Geoffrey F S Lim, Gregory E Merz, Michael D McCann, Jocelyn M Gruskiewicz, Martin J Serra

RNA· April 2012

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The best defense: a guide to disciplinary proceedings before the Minnesota Board of Medical Practice.
Gregory Merz

Minn Med· April 2009

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